1291-Genoarchitecture & Organization of Mouse Basal Ganglia

Paper Talk · Jul 17, 2026 · 22m

This research provides a comprehensive three-dimensional map of the mouse basal ganglia and thalamic parafascicular nucleus by integrating genetic data with neural connectivity. By analyzing transcriptomic cell types and viral tracing, the authors delineated specific subdivisions within these brain regions that correlate with organized inputs from the cerebral cortex. The study reveals that these subdivisions serve as structural foundations for parallel processing, where unique modules of the cortex communicate with specific cell types to manage motor control, learning, and emotion. The…