Micro 48: Paramyxoviruses
This episode explores the paramyxoviruses, enveloped negative-sense single-stranded RNA viruses known for their ability to induce cell fusion. Drawing from Murray’s Chapter 48, it examines how viral surface proteins drive respiratory infection and characteristic cytopathic changes.
The family includes:
* Respiratory syncytial virus (RSV)
* Parainfluenza viruses
* Measles virus
* Mumps virus
The defining mechanistic feature is the fusion (F) protein, which allows viral envelopes to merge with host cell membranes and, importantly, promotes the formation of syncytia - multinucleated giant cells…
The skinny
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