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#075_ STORY INSPIRE: Cancer Doctor Reveals: The Common Food That Could Be Making Cancer Worse · INSPIRE STORY

0:00
Speaker 1: Cancer is very preventable. When the medical establishment acknowledges what
0:03
Speaker 1: I know about this disorder, what's causing it, and what
0:06
Speaker 1: we're not doing to prevent it or treat it, it
0:08
Speaker 1: will be recognized as the greatest tragedy in the history
0:10
Speaker 1: of medicine.
0:11
Speaker 2: Thomas Seyfried is a professor of biology, genetics, and biochemistry who.
0:15
Speaker 1: Has dedicated the past 30 years gathering scientific evidence on
0:18
Speaker 1: what could be the true origin and prevention of cancer.
0:22
Speaker 1: Cancer is getting worse, and there's no major advance in
0:24
Speaker 1: reducing death rates, and I can speak to the reasons
0:27
Speaker 1: for that. All major cancer research centers think cancer is
0:31
Speaker 1: a genetic disease.
0:32
Speaker 2: You believe otherwise.
0:33
Speaker 1: It's not whether you believe, it's what the data tell us.
0:35
Speaker 1: And the evidence is massive to support that cancer is
0:38
Speaker 1: a metabolic disorder. And the problem is we're doing everything
0:40
Speaker 1: we possibly can in our lifestyle to induce it. The
0:44
Speaker 1: scientific evidence is there. Like, for example, we know that
0:46
Speaker 1: cancer was extremely rare in African tribes that were living
0:50
Speaker 1: according to the traditional ways. But when modern lifestyle entered
0:53
Speaker 1: into their societies, cancer out of control. We even did
0:56
Speaker 1: a study on dogs. We know that wolves in the
0:58
Speaker 1: wild don't die from cancer, but cancer is the number
1:01
Speaker 1: one killer of domestic dogs.
1:03
Speaker 2: Why?
1:04
Speaker 1: It's because of our lifestyle issues. And a lot of
1:07
Speaker 1: us are doing things without the knowledge that it would
1:09
Speaker 1: put us at risk. But with metabolic therapy, you can
1:11
Speaker 1: use it as both a prevention and a treatment. And
1:13
Speaker 1: we're seeing more and more of hormonal cancer patients outliving
1:17
Speaker 1: their predictability because of this. And let me tell you
1:19
Speaker 1: one thing and remember it. If you do metabolic therapy,
1:21
Speaker 1: you can actually reduce risk for cancer. You can take
1:24
Speaker 1: away the fear.
1:25
Speaker 2: And when you say metabolic therapy, tell me what those
1:27
Speaker 2: things are.
1:27
Speaker 1: Number one.
1:31
Speaker 2: Before this episode starts, I have a small favor to
1:33
Speaker 2: ask from you. Two months ago, 74% of people that
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Speaker 2: and the bigger the channel gets, as you've seen, the
1:52
Speaker 2: bigger the guests get. Thank you and enjoy this episode.
1:59
Speaker 2: Professor Seyfried. If someone walks up to you on the
2:01
Speaker 2: street and they know nothing about science, they know nothing
2:04
Speaker 2: about medicine, et cetera, and they asked you, what do
2:07
Speaker 2: you do and why do you do it? How would
2:08
Speaker 2: you respond?
2:09
Speaker 1: I'm a professor of biology at Boston College. So in
2:13
Speaker 1: that role, I spend a lot of my time working
2:16
Speaker 1: with undergraduates and graduate students in training them to be
2:20
Speaker 1: scientific literate in various aspects of biology. The research program
2:26
Speaker 1: that we have at the university is also focused on
2:31
Speaker 1: understanding how to manage cancer better, how it originates and
2:35
Speaker 1: how to prevent it.
2:37
Speaker 2: How much of a problem is cancer globally? What are
2:40
Speaker 2: the sort of headline statistics on the macro view of
2:43
Speaker 2: cancer for someone that really doesn't know?
2:45
Speaker 1: Yeah, well, it's getting worse. I can't say, it's in
2:49
Speaker 1: the millions. I know precisely what's going on in this
2:53
Speaker 1: country because the American Cancer Society every year distributes the
2:58
Speaker 1: data on cancer. We have almost 2 million new cases
3:04
Speaker 1: diagnosed per year in the United States. And we have 1,700
3:09
Speaker 1: people a day dying from cancer in the United States,
3:14
Speaker 1: which comes to about 70 people per hour in the
3:17
Speaker 1: United States. Now, when I went to China, I looked
3:21
Speaker 1: at some numbers there, and it was 8,000 people a
3:23
Speaker 1: day are dying from cancer. Obviously, the population is so
3:28
Speaker 1: much larger. And I don't know what it is in
3:31
Speaker 1: the UK. I mean, we'd have to go to their
3:33
Speaker 1: cancer registries. But what we do know is that it's
3:37
Speaker 1: supposed to be a lot worse by 2050 than it
3:40
Speaker 1: is today. So there seems to be no reduction in
3:43
Speaker 1: death suffering for this disease. And I can speak to
3:48
Speaker 1: the reasons for that. But right now, I would say
3:51
Speaker 1: it's a global epidemic of cancer. It's not getting better.
3:56
Speaker 1: It's getting worse. More people are dying from it. There's
3:58
Speaker 1: no major advance in reducing death rates. So it's a
4:02
Speaker 1: great tragedy. And when we understand what's causing it and
4:08
Speaker 1: what we're not doing to prevent it or treat it,
4:10
Speaker 1: it'll be recognized as the singular greatest tragedy in the
4:14
Speaker 1: history of medicine worldwide. When they come to know what
4:18
Speaker 1: I know about this disorder and then they realize what
4:21
Speaker 1: we've been doing, in a misdirected way, it will be
4:25
Speaker 1: recognized as the greatest tragedy in the history of medicine.
4:29
Speaker 2: What types of cancer are people dying from? What is
4:32
Speaker 2: the most popular types of cancer for men and women?
4:34
Speaker 1: Well, it's always been lung cancer, pretty much for men
4:37
Speaker 1: and women. Lung cancer has always been the number one,
4:40
Speaker 1: but we have pancreatic breast cancer, colon cancer. These are
4:44
Speaker 1: all on the rise. Colon cancer is on the rise.
4:46
Speaker 1: Pancreatic cancer is on the rise in this country. I
4:50
Speaker 1: can't speak for other countries specifically, They may vary slightly
4:55
Speaker 1: due to diet and lifestyle issues. But lung cancer has
4:57
Speaker 1: always been recognized as the number one cancer.
5:01
Speaker 2: How many people in the United States then, based on
5:04
Speaker 2: the statistics, would develop cancer?
5:06
Speaker 1: Well, it seems to increase every year. So it's kind
5:09
Speaker 1: of a moving target. It doesn't seem to go down.
5:13
Speaker 1: What it is today, I don't know. But what I
5:16
Speaker 1: do know is the numbers of people that are dying
5:18
Speaker 1: each day. Because the American Cancer Society comes out with
5:23
Speaker 1: I think it's 612,000 people will die this year, 2024,
5:28
Speaker 1: from cancer in this year. So divide it by 365,
5:33
Speaker 1: and it comes out to just about 1,700 people a day.
5:36
Speaker 1: Divide that number by 24, and you get about 70
5:39
Speaker 1: people an hour, based on the numbers provided to us
5:43
Speaker 1: from the American Cancer Society. When they say we've made
5:47
Speaker 1: major advances in cancer incidences, right? So in the 1990s,
5:53
Speaker 1: they instituted the anti-smoking campaigns. So today, if you read,
5:58
Speaker 1: they say we have reduced cancer deaths by 31% or 32%. Wow,
6:03
Speaker 1: that sounds really impressive. So what they do is they
6:07
Speaker 1: take the number. This is what the American Cancer Society
6:11
Speaker 1: has done. It's published in their papers. OK, if we
6:14
Speaker 1: didn't stop smoking in the 90s and everybody continued to smoke,
6:19
Speaker 1: the trajectory would be very, very high. Because we stopped smoking,
6:25
Speaker 1: we have 33% lower death than if we didn't stop smoking.
6:29
Speaker 1: But the trajectory is continuing to increase, maybe not as
6:33
Speaker 1: steep as it would have been had we continued to smoke.
6:36
Speaker 1: So it was clearly a prevention. It had nothing to
6:39
Speaker 1: do with a treatment. It had to do with prevention
6:41
Speaker 1: that was giving Oh, we've made major advances in reducing
6:46
Speaker 1: cancer death rates. Yeah, because people stopped smoking. Many, many people,
6:51
Speaker 1: more people would have died had they not smoked. So
6:53
Speaker 1: we have people that are not real people. We're just
6:57
Speaker 1: looking at what would have happened if we didn't stop smoking.
7:01
Speaker 2: What are the leading causes of death worldwide in terms
7:04
Speaker 2: of diseases? I hear that heart disease is number one.
7:09
Speaker 1: I think that heart disease is number one. Cancer is
7:12
Speaker 1: number two.
7:13
Speaker 2: Okay. And there are many different types of cancer, right?
7:16
Speaker 2: There's hundreds of different forms of cancer.
7:20
Speaker 1: If you look under the electron microscope or a correction,
7:23
Speaker 1: even a light microscope, this is how most cancers are
7:25
Speaker 1: diagnosed by light microscopy. You look under the microscope and
7:29
Speaker 1: you see a bunch of cells that are dysmorphic in
7:32
Speaker 1: the way they look and then they all have genetic
7:34
Speaker 1: defects and all this kind of stuff. But they all
7:37
Speaker 1: have one thing in common. They depend on a fermentation,
7:41
Speaker 1: energy without oxygen. So all cancers are a singular type
7:44
Speaker 1: of disease. It's just that they happen in different tissues.
7:47
Speaker 1: But when you look at the underlying problem, they're all very,
7:50
Speaker 1: very similar. They can't live without a fermentation, which means
7:53
Speaker 1: energy without oxygen. So that's the common pathophysiological problem in
7:57
Speaker 1: all cancers, whether it's a colon, brain, breast, bladder, skin, lung.
8:04
Speaker 1: We've looked at all these cancers and they're all essentially
8:08
Speaker 1: using the same mechanism to grow out of control.
8:11
Speaker 2: So what is that fermentation you mentioned?
8:13
Speaker 1: Fermentation is energy without oxygen.
8:15
Speaker 2: What does that mean?
8:17
Speaker 1: We breathe air and we exhale CO2 and water vapor.
8:21
Speaker 1: And those are the waste products of the food that
8:23
Speaker 1: we eat. Everything is broken down and combusted in our
8:26
Speaker 1: mitochondria of the cell. And the waste products are CO2
8:30
Speaker 1: and water vapors. Those are the waste products. But If
8:33
Speaker 1: you and I were to stop breathing for any particular
8:37
Speaker 1: time period, our bodies would fill up with lactic acid
8:42
Speaker 1: and succinic acid, like if we were to have a
8:44
Speaker 1: heart attack or when somebody has a heart attack. They
8:47
Speaker 1: don't die instantly. If they're there for five or seven
8:52
Speaker 1: minutes without oxygen, they may die because the brain dies.
8:55
Speaker 1: But if you can get the heart to beat again
8:57
Speaker 1: and get oxygen back in the system, you can come
9:00
Speaker 1: alive again. But when we have that massive interruption of
9:04
Speaker 1: oxygen into our body. The cells immediately turn on these
9:12
Speaker 1: ancient pathways to get energy without oxygen for a short
9:16
Speaker 1: period of time. And that's the sugar glucose, which is
9:19
Speaker 1: already in our bloodstream from the food we eat, and
9:22
Speaker 1: the amino acid glutamine, which is an amino acid in
9:26
Speaker 1: our bloodstreams. Highest level of amino acid is the glutamine.
9:30
Speaker 1: These two fuels are now burned for energy, obtain energy
9:34
Speaker 1: without oxygen. These pathways upregulate, and you can get ATP,
9:40
Speaker 1: which is energy, to keep you alive for a short
9:42
Speaker 1: period of time. But your bloodstream is filling up with
9:45
Speaker 1: the waste products called lactic acid and succinic acid. Lactic
9:49
Speaker 1: acid is coming from glucose to sugar, and succinic acid
9:53
Speaker 1: is coming from the amino acid glutamine. And they build up,
9:56
Speaker 1: and that tells you you're fermenting. You're getting energy without
9:59
Speaker 1: oxygen because you not breathing. Very simple. You're not breathing,
10:02
Speaker 1: but I'm not dead yet. Now, of course, if you
10:04
Speaker 1: don't get it for very long, you die. It's just that. Now,
10:08
Speaker 1: the other way you can stop oxygenation in our bodies
10:11
Speaker 1: quickly is with the poison cyanide. So if we, God forbid,
10:17
Speaker 1: we were to take cyanide, we'd be both dead within
10:19
Speaker 1: a minute. Because our bodies are completely shut down of
10:24
Speaker 1: energy from oxygen. Now here's the cancer cell. The cancer
10:28
Speaker 1: cell can live in cyanide. Cyanide does not kill a tumor, okay?
10:35
Speaker 1: Otto Warburg showed this a long time ago, and we've
10:37
Speaker 1: also shown the same thing in our lab. Others have
10:40
Speaker 1: shown this. The interesting thing is when you look at
10:42
Speaker 1: cancer cells, Even in the presence of oxygen, even in oxygen,
10:46
Speaker 1: they're throwing out lactic acid and succinic acid. What does
10:50
Speaker 1: that mean? That means the organelle inside the cell that
10:55
Speaker 1: generates energy is not efficient. It's inefficient. And the cells
10:59
Speaker 1: are using ancient fermentation. And when I say ancient fermentation,
11:03
Speaker 1: you have to realize the Earth is four and a
11:05
Speaker 1: half billion years old. The organisms that existed on our
11:10
Speaker 1: planet Two and a half billion years ago, we're all fermenters.
11:14
Speaker 1: There was no oxygen in the atmosphere until the photosynthetic
11:16
Speaker 1: bacteria started making oxygen. There were living cells. They had
11:20
Speaker 1: no oxygen. And they were growing like crazy, unregulated growth,
11:25
Speaker 1: just unregulated. What's going on here? And they would die
11:28
Speaker 1: as soon as the fermentable fuels were dissipated. As they
11:31
Speaker 1: gobbled up everything, they would just die. So they lived
11:33
Speaker 1: as long as they could reproduce and have fermentation fuels.
11:37
Speaker 1: The cancer cell in our body is doing nothing than
11:40
Speaker 1: falling back on these ancient fermentation pathways that become accelerated,
11:45
Speaker 1: upregulated in the tumor cell because the efficiency of the
11:49
Speaker 1: energy coming from the mitochondria is now depleted. It's defective
11:54
Speaker 1: in many different ways. So this is very clear. And
11:57
Speaker 1: this happens in lung cancer, colon cancer. We've looked at
11:59
Speaker 1: all the major cancers. And we found out these common
12:02
Speaker 1: defects are seen in all the cancers. So they're all
12:06
Speaker 1: very similar in their metabolism. They're very different in what
12:08
Speaker 1: they look like under the microscope. Lung doesn't look like colon,
12:11
Speaker 1: doesn't look like brain. They're very different genetically. They're all
12:14
Speaker 1: different from each other, but they're all common in a
12:17
Speaker 1: dependency on this ancient pathway of energy metabolism.
12:21
Speaker 2: Can you take me back? You mentioned a guy called
12:24
Speaker 2: Walt Wahlberg there.
12:25
Speaker 1: Yeah.
12:25
Speaker 2: Can you take me back on the journey that the
12:28
Speaker 2: scientific community, or at least you have been on, to
12:30
Speaker 2: arrive at the conclusion that the central sort of causal factor,
12:33
Speaker 2: at least an indication of the causal factor of cancer
12:36
Speaker 2: lies in this shift in energy systems. Where did this
12:40
Speaker 2: understanding start in research?
12:42
Speaker 1: Well, it started with Otto Warburg, for sure, in the 1920s.
12:46
Speaker 1: The other linkage, before I tell you what Otto Warburg did,
12:49
Speaker 1: because I was like everybody else, I thought cancer was
12:52
Speaker 1: a genetic disease. And I heard about Warburg, didn't really
12:55
Speaker 1: know what he was talking about or invested any time
12:59
Speaker 1: thinking about what he said. But Lyndon Neblings, was a
13:03
Speaker 1: PhD nursing student at Case Western Reserve University in Ohio.
13:08
Speaker 1: And she took these two little hopeless kids, brain cancer.
13:12
Speaker 1: We call hopeless cases when they have no predictability of
13:16
Speaker 1: long-term survival. And she gave them a ketogenic diet, the
13:20
Speaker 1: lower blood sugar. And she was able to rescue these kids.
13:25
Speaker 1: One eventually died. The other one was lost to follow-up.
13:28
Speaker 1: And she said her strategy was based on what Otto
13:31
Speaker 1: Warburg had said about glucose and cancer. So then I said, Warburg?
13:35
Speaker 1: I said, who the hell? Let me go back and
13:37
Speaker 1: check out who this guy was and what he did.
13:39
Speaker 1: Because I was seeing similar things in the mouse with
13:41
Speaker 1: that drug. It was lower in glucose. And we were
13:45
Speaker 1: shrinking these tumor cells. And we published a paper, one
13:49
Speaker 1: of the first ever papers, linking that how high your
13:52
Speaker 1: blood sugar is determines how fast your tumor will grow
13:55
Speaker 1: in the mice. And now this has been replicated in
13:57
Speaker 1: all human cancers. The higher your blood sugar, the faster
14:01
Speaker 1: the tumor grows. The lower the blood sugar, the slower
14:03
Speaker 1: the tumor grows. Undeniable for all different human mouse cancers.
14:07
Speaker 2: Wow.
14:08
Speaker 1: So Warburg had said this a long time ago, back
14:10
Speaker 1: in the 1920s. He was taking slices of all kinds
14:15
Speaker 1: of human and rat mouse tumors and slicing them up.
14:18
Speaker 1: And he noticed something really strange about these cancers. They
14:22
Speaker 1: take in less oxygen. compared to the normal tissue from
14:25
Speaker 1: which they came. Wow, so they're kind of like oxygen deprived.
14:29
Speaker 1: And they were throwing out this lactic acid waste product
14:32
Speaker 1: that he was saying. And they were taking in so
14:35
Speaker 1: much more glucose than the normal. So the normal cells
14:38
Speaker 1: take in just a little bit of glucose, and they
14:40
Speaker 1: can make tremendous energy from a tiny amount. This guy
14:43
Speaker 1: was taking in huge amounts of glucose, but not fully
14:46
Speaker 1: metabolizing it to CO2 and water, but dumping it out
14:50
Speaker 1: as lactic acid, which is a a breakdown product of
14:53
Speaker 1: glucose that is not fully metabolized in the cell. Wow,
14:57
Speaker 1: he said, this is unbelievable. And then he did all
15:00
Speaker 1: kinds of tissue. I looked at his data. It was unbelievable.
15:02
Speaker 1: He was cutting humans, mice, rats, and seeing the same
15:05
Speaker 1: thing over and over again. And he was saying the
15:10
Speaker 1: origin of cancer has to do with something in the
15:13
Speaker 1: ability of the mitochondrion, the organelle, to generate efficient energy
15:17
Speaker 1: from oxygen.
15:18
Speaker 2: So the mitochondria is the part of the cell that
15:21
Speaker 2: creates energy?
15:22
Speaker 1: It's the part of the cell that creates energy through
15:25
Speaker 1: oxidative phosphorylation, which is burning energy using oxygen. Okay.
15:30
Speaker 2: Okay.
15:31
Speaker 1: So it's like an engine. It's an engine, a very
15:33
Speaker 1: highly efficient engine. This is an organelle. You have to
15:36
Speaker 1: realize we have the cell.
15:38
Speaker 2: Yeah.
15:38
Speaker 1: And we have a nucleus that everybody knows about, this nucleus.
15:41
Speaker 1: And then we have all these little organelles in there.
15:43
Speaker 1: We have lysosomes and we have the mitochondrion, which is
15:47
Speaker 1: like a spaghetti network inside the cell. They fuse. It's
15:51
Speaker 1: actually a second living cell. It's a second living organism
15:54
Speaker 1: inside our cells.
15:55
Speaker 2: And to simplify what they do, the mitochondria, they convert
15:59
Speaker 2: oxygen and glucose into energy?
16:00
Speaker 1: Yes, they combust energy. The foods that we eat have
16:05
Speaker 1: carbon-hydrogen bonds, okay? And we break those down inside our mitochondria.
16:11
Speaker 1: And when we break those bonds down, we create a
16:14
Speaker 1: hydrogen gradient, and we dissipate that gradient through an impeller
16:18
Speaker 1: mechanism that generates energy like crazy. It's unbelievable. Very efficient,
16:22
Speaker 1: highly efficient. But the cancer cell has corruption in that system.
16:26
Speaker 1: But it doesn't happen overnight. As Warburg said, if you
16:30
Speaker 1: break that system too acutely and too fast, the cell
16:32
Speaker 1: will die. It doesn't have the... So you have to
16:35
Speaker 1: have two things to get from oxidative phosphorylation to energy
16:41
Speaker 1: with minimal oxygen fermentation.
16:43
Speaker 2: Sorry, just to keep it simple. From a normal cell
16:45
Speaker 2: to a cancer cell.
16:46
Speaker 1: From a normal cell to a cancer cell doesn't happen overnight.
16:49
Speaker 2: Okay.
16:50
Speaker 1: It's a chronic damage to the ability of that organelle
16:54
Speaker 1: inside the cell to generate efficient energy. So all we
16:58
Speaker 1: have to know with cancer is how are they growing
17:02
Speaker 1: so rapidly? Why are they going out of control? How
17:04
Speaker 1: come it's so hard to kill them? Because as long
17:07
Speaker 1: as you have those fermentable fuels that drive this ancient
17:11
Speaker 1: fermentation pathway, They will continue to grow. They're very hard
17:15
Speaker 1: to kill.
17:16
Speaker 2: And the fermenting fuels are glucose and- And glutamine. Glutamine. Yeah. Okay.
17:21
Speaker 1: So here, let me tell you in a nutshell. Are
17:23
Speaker 1: you ready? Brace yourself. Are you ready? I'm ready. Are
17:26
Speaker 1: you braced? Are you braced?
17:28
Speaker 2: Sufficiently braced.
17:29
Speaker 1: He's sufficiently braced. Okay. So a solution to the cancer problem,
17:35
Speaker 1: to manage cancer without toxicity, is to simultaneously restrict the
17:41
Speaker 1: two fuels- that are needed to drive this dysregulated growth
17:45
Speaker 1: while transitioning the whole body off to a fuel that
17:49
Speaker 1: the tumor cells can't use, which is fatty acids and
17:52
Speaker 1: ketone bodies. So when we take the cancer patients or
17:56
Speaker 1: the mice, we put them into a calorie restriction, lowering
18:00
Speaker 1: the blood sugar that I said is one half of
18:04
Speaker 1: the two fuels. You can lower that down really, really low.
18:07
Speaker 1: And then we use specific drugs to target the glutamine.
18:11
Speaker 1: And together, we can selectively restrict the two fuels while
18:15
Speaker 1: we transition the whole body over to ketones. We, as
18:19
Speaker 1: a species, evolved to be in nutritional ketosis for the
18:23
Speaker 1: majority of our existence as a species, like one and
18:26
Speaker 1: a half million years. For centuries and centuries, thousands and
18:30
Speaker 1: thousands of years, our species, you and me, our ancestors,
18:35
Speaker 1: were always in a state of nutritional ketosis. Because there
18:38
Speaker 1: was very few carbohydrates in the environment for them to
18:41
Speaker 1: be consuming, right? So the cancer cell, the body, you
18:45
Speaker 1: and I could, if we stopped eating and we took
18:47
Speaker 1: a low-carbohydrate diet and just did water-only fasting, we would
18:50
Speaker 1: get into nutritional ketosis, where the normal cells, our brain,
18:55
Speaker 1: our kidneys, our heart, can be burning these ketone bodies
18:58
Speaker 1: because they have a good mitochondria and they can burn
19:01
Speaker 1: these fuels effectively. The tumor cells have a bad mitochondria.
19:04
Speaker 1: They can't burn those fuels. They're dependent on glucose and glutamine.
19:07
Speaker 1: we can replace glucose and glutamine with ketone bodies in
19:10
Speaker 1: the normal cells of our... So we selectively marginalize these
19:13
Speaker 1: tumor cells slowly over time. They slowly start to die,
19:18
Speaker 1: the blood vessels disappear, and the body comes in and
19:21
Speaker 1: dissolves them.
19:22
Speaker 2: So for someone that has never heard the term keto before,
19:26
Speaker 2: ketosis or ketones, in a simple way, what are ketones?
19:31
Speaker 1: Ketones are water-soluble breakdown products of fatty acids, okay? They're beta-hydroxybutyrate, acetoacetate.
19:37
Speaker 1: These are small molecules that are water-soluble. The liver throws
19:41
Speaker 1: them out like crazy. Kidney a little bit, but mostly liver.
19:44
Speaker 1: So as I told you earlier, when we don't eat,
19:50
Speaker 1: you get anxious, mainly because our brains are addicted to glucose.
19:53
Speaker 1: It's like cocaine and nicotine and whatever. You start getting
19:57
Speaker 1: all antsy. I haven't eaten anything. What's going on? So
20:02
Speaker 1: then once the body realizes you ain't going to eat anything,
20:06
Speaker 1: we have to start mobilizing out of our fat resources.
20:09
Speaker 1: And the fats go into the bloodstream as triglycerides, which
20:13
Speaker 1: are three fatty acids attached to a glycerol backbone. They
20:17
Speaker 1: go to the liver. The liver chops them up and
20:19
Speaker 1: puts out these little water-soluble ketone bodies. The name ketone
20:25
Speaker 1: body is kind of a weird thing from biochemistry, but
20:28
Speaker 1: they're called ketone bodies. And they can supply the brain
20:32
Speaker 1: with energy, the heart with energy. And not only that,
20:35
Speaker 1: they're a super fuel. It's unbelievable. that mitochondria burns these ketones. Okay,
20:40
Speaker 1: but their energy, remember I was talking about how energy
20:43
Speaker 1: efficient the mitochondria become? When they burn ketones, they become
20:46
Speaker 1: even more energy efficient. It's unbelievable how, they don't need
20:50
Speaker 1: as much oxygen to generate more energy. That's why they,
20:53
Speaker 1: my colleagues called, and some of the greats in the
20:57
Speaker 1: biochemistry field called them super, super fuel, because you can
21:01
Speaker 1: get more energy bang for buck burning a ketone body
21:04
Speaker 1: than you can burning a pyruvate coming from glucose. or
21:07
Speaker 1: even a fatty acid. And the biochemistry for that is interesting.
21:13
Speaker 1: But the bottom line is when you transition away from
21:15
Speaker 1: these fuels to keto, don't forget, we evolved. Our ancestors
21:19
Speaker 1: were always in a state of ketosis. You get into
21:22
Speaker 1: that state by consuming very few carbohydrates and having a
21:25
Speaker 1: lot of energy. And this is the way our ancestors were.
21:28
Speaker 2: So what can we learn from our ancestors about cancer?
21:31
Speaker 2: How prevalent was cancer when we look back at our ancestors,
21:35
Speaker 2: if they were often in a state of ketosis?
21:37
Speaker 1: Yeah, well, it's hard to determine from skeletal records, but
21:42
Speaker 1: I think we can look at modern man who live
21:48
Speaker 1: according to their traditional ways. You know, Albert Schweitzer, the
21:54
Speaker 1: great humanitarian physician, went to Africa and looked at Africans
21:57
Speaker 1: that were living according to the traditional ways. He said,
22:01
Speaker 1: one of the weirdest things, they don't have cancer. It's like, what?
22:04
Speaker 1: The cancer was extremely rare. in Africans, Inuits living in
22:10
Speaker 1: the areas, British when they came in looking at the
22:15
Speaker 1: health conditions of folks that lived in the Arctic Circle.
22:18
Speaker 1: Cancer was not there. They had other things, but they
22:20
Speaker 1: didn't have cancer. Aboriginal folks. So it seems as though
22:25
Speaker 1: our living, we can't go back 50,000 years ago because
22:30
Speaker 1: we don't have people to examine. But we have people
22:32
Speaker 1: to examine today. And that was one of the things
22:34
Speaker 1: Schweitzer and several other physicians from Europe would go to Africa.
22:38
Speaker 1: And they would look at some of these tribes that
22:40
Speaker 1: were traditional. And they were saying, whoa, what's going on
22:43
Speaker 1: with these Africans? How come they don't have cancer? But
22:45
Speaker 1: when modern diet and lifestyle entered into their societies, cancer
22:50
Speaker 1: out of control.
22:51
Speaker 2: What about our other primate cousins?
22:54
Speaker 1: Yeah. There's never been a documented case of breast cancer
22:59
Speaker 1: in a female chimpanzee. and they're 98% similar to us
23:03
Speaker 1: in gene and protein sequence. You know, what's going on
23:06
Speaker 1: with that? Monkeys, they don't generally form cancer. They're eating.
23:11
Speaker 1: They're not eating what we eat, okay? Don't forget, we
23:14
Speaker 1: did not evolve to eat pork pies and Dunkin' Donuts,
23:19
Speaker 1: jelly-filled donuts and pizzas. We did not. Our ancestors did
23:23
Speaker 1: not eat this, right? We were killing and eating animals
23:26
Speaker 1: As I said, we ate everything that walked, crawled, flew,
23:29
Speaker 1: or swam on this planet became part of our diet.
23:32
Speaker 1: We did not have donuts on every corner, delicatessens on
23:36
Speaker 1: every corner. We evolved over this period of time, just
23:39
Speaker 1: like our primate ancestors. The animals, chimps and gorillas and
23:45
Speaker 1: things that you see in the zoos are fed their
23:48
Speaker 1: natural diets as if they were living in their habitat,
23:51
Speaker 1: their natural habitat, whether it was in South America, Africa,
23:54
Speaker 1: or wherever it was. We're not throwing in jelly donuts
23:57
Speaker 1: every day and pizza pie into the chimpanzee pen. And
24:01
Speaker 1: as a matter of fact, I even went to the
24:03
Speaker 1: zoo down here in Boston, Franklin Park Zoo, and also
24:07
Speaker 1: at the San Diego Zoo. I said, how come you
24:11
Speaker 1: guys don't give these guys, run down and get a
24:13
Speaker 1: big pizza for these animals? Oh, no, it would be
24:15
Speaker 1: animal cruelty. Their systems aren't geared for this. Well, neither
24:18
Speaker 1: are we. We have an obesity epidemic. We have all
24:25
Speaker 1: these different chronic diseases. Why? We didn't evolve to eat
24:28
Speaker 1: all this crap that we're eating today. So what I've
24:31
Speaker 1: told many people in these podcasts is that our food
24:34
Speaker 1: science and technology and our society's technology has evolved so
24:38
Speaker 1: much faster than our biology.
24:41
Speaker 2: Can you explain to me, in simple terms, the role
24:43
Speaker 2: that exercise is playing in staving off cancer?
24:46
Speaker 1: Well, exercise lowers blood sugar. And it also lowers glutamine.
24:50
Speaker 1: So the two fuels that are driving– now we can't
24:54
Speaker 1: completely remove glutamine by exercise, that's for sure. But my
24:58
Speaker 1: late good friend George Cahill published some papers on showing
25:01
Speaker 1: how exercise could actually lower glutamine availability. So it's a
25:06
Speaker 1: little bit of a push. But you're also– when you exercise,
25:10
Speaker 1: you're burning and you're not eating a lot of carbs.
25:12
Speaker 1: Your mitochondria are burning ketones, and the oxygenation from all
25:15
Speaker 1: the exercise is keeping those mitochondria super healthy at their
25:19
Speaker 1: highest level of energy efficiency.
25:22
Speaker 2: So exercise— You're building muscle as well, aren't you?
25:24
Speaker 1: Yeah, you're building— well, you can build muscle, but you're certainly
25:26
Speaker 1: getting aerobic exercise. Oxygen is coming in, and you're burning ketones,
25:31
Speaker 1: which I already told you is a super fuel. So
25:34
Speaker 1: your body is super healthy. These bodies from the Paleolithic period,
25:39
Speaker 1: these men were jacked. There was no obesity in these people.
25:42
Speaker 1: They had tremendous energy. They're not dying from the things
25:45
Speaker 1: that are killing us. They're dying from injuries and infections.
25:49
Speaker 2: When you described this slow and gradual shift in the
25:53
Speaker 2: cell as it moves to this sort of ancient system,
25:56
Speaker 2: it sounded very gradual. So in my head, I thought, okay,
25:59
Speaker 2: so does that mean that the cancer is a gradual
26:03
Speaker 2: process that is kind of building up in me or
26:06
Speaker 2: isn't building up in me based on the lifestyle decisions
26:09
Speaker 2: I'm making and my environmental factors? right now? I'm trying
26:14
Speaker 2: to say, does cancer start slowly, years before you've tried
26:19
Speaker 2: to manage it?
26:20
Speaker 1: Yeah, it is a gradual process, but it can be
26:22
Speaker 1: impacted by several provocative agents from the microenvironment. Lack of exercise.
26:30
Speaker 1: So we're not exercising nearly as much as our Paleolithic ancestors,
26:34
Speaker 1: bar none, right? We have massive amounts of processed carbs
26:38
Speaker 1: in our diets. We have a lot of emotional stress. mental,
26:43
Speaker 1: emotional stress that's impacting negatively on our biology. We have
26:51
Speaker 1: lack of sleep. Sleep, a lot of us, because we
26:55
Speaker 1: have stresses, you have to have, when you put all
26:57
Speaker 1: of these impactful things together in one person, you can
27:01
Speaker 1: put yourself at risk for cancer, all of which will
27:04
Speaker 1: damage and reduce the efficiency of mitochondria. And also the
27:10
Speaker 1: joy of living Having friends and friendships and this kind
27:14
Speaker 1: of thing reduces stress in a lot of different ways,
27:16
Speaker 1: makes people enjoy getting up and having a nice day
27:20
Speaker 1: rather than being depressed or these kinds of things. You
27:23
Speaker 1: put all this together and you put yourself in a
27:27
Speaker 1: diet and a lifestyle that puts you at risk for
27:29
Speaker 1: damage to oxidative phosphorylation and the transition from one form
27:33
Speaker 1: of energy to a fermentation energy.
27:35
Speaker 2: And what I'm trying to understand, is that a gradual transition?
27:38
Speaker 1: It's a gradual transition. You have to be able to
27:40
Speaker 1: do that. And how long does it take for a colon,
27:44
Speaker 1: a group of cells in a crypt of your colon
27:47
Speaker 1: to transition from one stage to another? You have to
27:50
Speaker 1: be constantly under stress, those cells in that organ. Now,
27:54
Speaker 1: why somebody gets colon cancer, another person gets breast cancer,
27:57
Speaker 1: another person gets bladder cancer, and some person gets a
27:59
Speaker 1: brain cancer and all these different kinds of cancers. Whatever happened,
28:03
Speaker 1: the process was causing a gradual disruption of oxidative phosphorylation,
28:09
Speaker 1: oxidative respiration. and a gradual transition to a fermentation. Like
28:14
Speaker 1: in the brain, the neurons rarely, if ever, get cancer.
28:18
Speaker 1: But the glial cells that support neurons, they are usually
28:21
Speaker 1: the source of the origin of cancer in the brain
28:24
Speaker 1: for those kinds of cells. And you can look at
28:26
Speaker 1: different cells, and some are more or less prone. And
28:28
Speaker 1: why this guy got lung cancer from smoking cigarettes, this
28:31
Speaker 1: guy got bladder cancer from smoking cigarettes. How did it
28:34
Speaker 1: all start? It all started from a population of cells
28:38
Speaker 1: in one of those organs having a chronic, not instant,
28:42
Speaker 1: a chronic interruption of oxidative energy followed by an upregulation
28:47
Speaker 1: of this fermentation energy.
28:49
Speaker 2: So really we need to be thinking about all the
28:50
Speaker 2: things that have caused dysfunction in the mitochondria.
28:52
Speaker 1: Absolutely.
28:53
Speaker 2: I want to get a list of the key things
28:55
Speaker 2: that are associated with causing this dysfunction.
28:57
Speaker 1: Okay, carcinogens.
28:58
Speaker 2: Okay, so carcinogens.
28:59
Speaker 1: Yeah, and you know, there's many, asbestos, there's all kinds
29:02
Speaker 1: of chemicals in the environment. You hear about this, oh,
29:05
Speaker 1: there's a whole list of carcinogens. And they put them
29:07
Speaker 1: on the on the labels on different chemicals. They say
29:10
Speaker 1: carcinogenic potential and whatever you have.
29:13
Speaker 2: What are the types of things that are carcinogenic that
29:15
Speaker 2: most people don't realize?
29:17
Speaker 1: Oh, well, now we're talking about microplastics. We're talking about.
29:21
Speaker 2: Is that in part what causes breast cancer? Because I
29:24
Speaker 2: always think about deodorant with breast cancer and... the stuff
29:27
Speaker 2: that we're kind of lathering onto our arms.
29:29
Speaker 1: Yeah, well, the one that was most interesting was the
29:32
Speaker 1: talcum powder one. How does talcum powder would cause ovarian cancer? Okay,
29:37
Speaker 1: it's taken up into the urogenital tract. and it forms
29:40
Speaker 1: a foci in a part of the ovarian tissue.
29:43
Speaker 2: What's a foci?
29:44
Speaker 1: A locus, like a collection of material. A foci is
29:50
Speaker 1: an area where, say, talcum materials would be accumulating. And
29:55
Speaker 1: that leads to an inflammatory... area of the body. And
30:01
Speaker 1: our immune system comes in to see what's going on.
30:04
Speaker 1: Our immune system is a healing machine. And they see
30:07
Speaker 1: something that's not normal. Normally, they would clean it up.
30:10
Speaker 1: But they throw cytokines and growth factors on there, leading
30:14
Speaker 1: to dysregulated damage to mitochondria and dysregulated. And then you
30:17
Speaker 1: get this tumor that starts.
30:19
Speaker 2: So if I get a talcum powder granule or whatever,
30:23
Speaker 2: and it goes into my body, my body then tries
30:25
Speaker 2: to attack it to sort it out. And in doing so,
30:29
Speaker 2: it creates inflammation, which leads to.
30:31
Speaker 1: Damage to mitochondria in a particular group of cells near
30:33
Speaker 1: that foci.
30:34
Speaker 2: Okay. And this is applicable to, I guess, a lot
30:36
Speaker 2: of different nanoparticles.
30:38
Speaker 1: Yeah. And microplastics are this now. They're looking at this.
30:41
Speaker 1: But then we have chemical carcinogens, tetrahydrochloride. There's all kinds
30:44
Speaker 1: of other things that can actually damage arsenics and these
30:48
Speaker 1: kinds of chemicals, urethane, anything that could chronically damage a mitochondrion, forcing...
30:56
Speaker 1: over time, forcing it to upregulate the fermentation, the energy
31:00
Speaker 1: without oxygen.
31:01
Speaker 2: Isn't this most things? I'm trying to figure out how
31:04
Speaker 2: to live my life.
31:05
Speaker 1: Yeah, well, that's why it was called the oncogenic paradox.
31:08
Speaker 1: But you can avoid that. That's why I'm saying, if
31:11
Speaker 1: you can keep your mitochondria healthy, exercise and reduce consumption
31:18
Speaker 1: of highly processed carbohydrates.
31:19
Speaker 2: Do I need to be avoiding these microplastics as well?
31:21
Speaker 1: You know, the problem with microplastics, they're very ubiquitous. We're
31:25
Speaker 1: not really sure We're just now becoming aware of it.
31:28
Speaker 1: Nobody really knew that before. Look it up. But it
31:33
Speaker 1: could cause small foci in different populations of cells. But,
31:37
Speaker 1: you know, it's very hard to really chronically damage mitochondria.
31:41
Speaker 1: Mitochondria are a tough organelle. The problem is we chronically
31:44
Speaker 1: abuse it without realizing what we need to do to
31:47
Speaker 1: keep it healthy. So even if you are exposed to
31:50
Speaker 1: chemical carcinogens, even if you are exposed to all these things,
31:53
Speaker 1: but you're keeping your body as healthy as you possibly can,
31:56
Speaker 1: you could possibly delay or even prevent the damage to
32:00
Speaker 1: the mitochondria, even though you are being exposed to this.
32:04
Speaker 1: So it's actually in your hands. You can actually reduce
32:09
Speaker 1: risk for cancer by knowing what keeps your mitochondria healthy.
32:14
Speaker 1: Vigorous exercise, fasting, water-only fasting. You know, it's very hard.
32:20
Speaker 1: Sometimes when we were putting mice on calorie restriction, it
32:23
Speaker 1: was hard to get them to get tumors. Their body
32:26
Speaker 1: was so healthy. This was shown years ago by a
32:29
Speaker 1: couple of scientists in mice, using mice that developed a
32:32
Speaker 1: lot of breast cancer. If you put them on a
32:35
Speaker 1: calorie-restricted diet, the incidence was way, way down. So cancer
32:38
Speaker 1: is very preventable. It's a very preventable disorder. It's just
32:42
Speaker 1: that we're doing everything we possibly can to induce it
32:46
Speaker 1: in our diet lifestyle.
32:48
Speaker 2: A lot of big institutions believe that cancer is a
32:50
Speaker 2: genetic problem. you believe otherwise?
32:57
Speaker 1: The evidence is striking. I mean, it's not whether you believe,
33:01
Speaker 1: it's what the data tell us. Okay. So according to
33:04
Speaker 1: the somatic mutation theory of cancer, mutations in the nucleus
33:08
Speaker 1: lead to dysregulated cell growth. That's the somatic mutation theory.
33:12
Speaker 1: In the mitochondrial metabolic theory, it's a transition from oxidative
33:15
Speaker 1: phosphorylation to a fermentation metabolism inside the cell. The mutations
33:22
Speaker 1: are Largely irrelevant. What do you mean by that? When
33:26
Speaker 1: the mitochondria become defective, they throw out ROS, reactive oxygen species,
33:33
Speaker 1: that are carcinogenic and mutagenic. Whoa, what does that mean?
33:36
Speaker 1: Causing mutations. So a lot of the mutations that we
33:39
Speaker 1: see in the nucleus of the tumor cell that is
33:42
Speaker 1: the subject of the somatic mutation theory are downstream effects
33:46
Speaker 1: of the dysfunction of the mitochondria. So the mitochondria is
33:49
Speaker 1: causing a downstream effect, which are mutations, which, according to
33:52
Speaker 1: the somatic mutation theory, are the cause of the dysregulated
33:55
Speaker 1: cell growth. Let me tell you why that's absolutely untrue.
33:59
Speaker 1: There's some cancer cells growing out of control that have
34:01
Speaker 1: no mutations and normally not discussable. How can that be?
34:04
Speaker 1: That's a challenge to the theory. If the theory says
34:07
Speaker 1: that all cancers have mutations and you have some cancers
34:10
Speaker 1: that have no mutations and they're growing out of control,
34:13
Speaker 1: that should say, oh, bell ring one. Then the somatic
34:17
Speaker 1: mutation people, people who think this, said, oh, okay, we
34:21
Speaker 1: have a problem here. Not all mutations are the ones
34:24
Speaker 1: that cause the dysregulated, only some. And we have a
34:27
Speaker 1: name for those some. That's called driver mutation. Okay, now
34:30
Speaker 1: it's a nice term. Because some of those mutations are
34:32
Speaker 1: called passengers. They don't really do anything. But the drivers
34:35
Speaker 1: are the ones that lead to the dysregulated cell growth.
34:38
Speaker 1: So we should be focusing our attention on these driver mutations.
34:41
Speaker 1: New evidence from the recent scientific literature, can you believe this?
34:45
Speaker 1: They're taking tissue, normal tissues from patients, different organs and
34:49
Speaker 1: things like this, from not patients, from normal people, no cancer,
34:52
Speaker 1: perfectly like yourself here. We would take tissue from you
34:55
Speaker 1: and say, oh my Christ, look at that. You got
34:56
Speaker 1: driver mutations in your esophagus and your different parts of
35:00
Speaker 1: your body. You got driver, but you don't have a tumor.
35:02
Speaker 1: What's going on with that? How do you explain that
35:04
Speaker 1: these driver mutations are causing dysregulated cell growth when we
35:07
Speaker 1: have thousands of driver mutations that are there that are
35:11
Speaker 1: not causing dysregulated cell growth? Oh, okay. That's another problem.
35:16
Speaker 1: The biggest devastating information against the somatic mutation theory is
35:20
Speaker 1: if you take the nucleus from a tumor cell, cleanly
35:22
Speaker 1: take it out of the tumor cell, and you have
35:25
Speaker 1: another normal cell here, you take the nucleus out of
35:28
Speaker 1: the normal cell and you put the tumor cell into
35:30
Speaker 1: that cytoplasm, you get regulated growth, no dysregulated growth. But
35:34
Speaker 1: if I have the normal cell and have a tumor cell,
35:37
Speaker 1: take the tumor nucleus out of there and take the
35:39
Speaker 1: normal nucleus and put it into the tumor cytoplasm, which
35:42
Speaker 1: contains defective mitochondria, dysregulated cell growth. This has been seen
35:47
Speaker 1: over and over and over again.
35:48
Speaker 2: So just to summarize that, so if you take the
35:50
Speaker 2: tumor nucleus out of the cell and put it into
35:52
Speaker 2: a normal healthy cell, everything's fine.
35:56
Speaker 1: Everything is fine.
35:57
Speaker 2: But if you take healthy cell nucleus and put it
35:59
Speaker 2: into a tumor cell, you still have the.
36:01
Speaker 1: Same- Dysregulated cell growth.
36:02
Speaker 2: Tumor growth, which means that it's not the nucleus.
36:05
Speaker 1: Absolutely.
36:06
Speaker 2: It's something else.
36:06
Speaker 1: It's something else. And that's the mitochondria. And I told you,
36:09
Speaker 1: then you have cancer cells with no mutations. And then
36:11
Speaker 1: you have driver mutations in normal cells that never become cancer.
36:14
Speaker 1: You put all those things together. And you have to
36:18
Speaker 1: be a hopeless ideologue to think that cancer is a
36:23
Speaker 1: genetic disease. It's a silent assumption in the field that
36:27
Speaker 1: cancer is a genetic... Every textbook of biology, cell biology,
36:30
Speaker 1: and bio... Cancer is a genetic disease.
36:32
Speaker 2: Why hasn't people's opinions changed despite the evidence that you present?
36:38
Speaker 1: It's a very difficult thing. It goes back to when
36:42
Speaker 1: you have one theory replacing another theory. It's called paradigm shifts.
36:48
Speaker 1: And all in history of science, paradigm shifts have been
36:51
Speaker 1: met with great, great resistance. The clearest one was the
36:56
Speaker 1: Copernican Revolution when for 1,800 years, astronomers in our society
37:06
Speaker 1: early astronomers thought the Earth was immovable in the center
37:09
Speaker 1: of the solar system. For 1,000, this was Claudius Ptolemy, Aristotle,
37:14
Speaker 1: and the Bible, and all these Earth is immovable, and
37:18
Speaker 1: the sun and the moon and the planets all revolve
37:20
Speaker 1: around the Earth. 1,800 years. Even Copernicus was working with
37:25
Speaker 1: these mathematical formulations. Koepp was being constantly confused until he said,
37:31
Speaker 1: what happens if we put the sun in the center
37:34
Speaker 1: of the solar system and consider the Earth as simply
37:36
Speaker 1: another planet that would revolve. All of a sudden, things
37:39
Speaker 1: started to make sense. And Giordano Bruno, a theologian, was
37:45
Speaker 1: put to death for suggesting that Copernicus was right. There
37:50
Speaker 1: was a tremendous resistance on the part of the Roman
37:53
Speaker 1: Catholic Church at that time. And this is the same
37:55
Speaker 1: thing that happened when Louis Pasteur said that germs, rather
38:01
Speaker 1: than bad air, are the cause of disease. So and
38:04
Speaker 1: when Darwin Wallace theory of evolution came, it's not special creation.
38:08
Speaker 1: It's natural selection that can explain this. These were massive
38:12
Speaker 1: paradigm changes in the history of science. And what we're
38:16
Speaker 1: seeing today is the same thing. The mitochondria is the
38:19
Speaker 1: center of the problem with cancer, not the nucleus. The mitochondria,
38:23
Speaker 1: it's a mitochondrial metabolic disease. And once you realize that,
38:27
Speaker 1: we're going to drop these death rates massively in a
38:29
Speaker 1: very number of years for sure.
38:32
Speaker 2: So if we take two paths, and if we realize
38:34
Speaker 2: that the mitochondria is the center of the dysfunction and
38:38
Speaker 2: ultimately disease in the cell, if we go down that path,
38:42
Speaker 2: what impact do you think that will have on the
38:43
Speaker 2: cancer statistics over the coming years?
38:46
Speaker 1: It'll drop it massively. I'm not going to say we'll
38:49
Speaker 1: get rid of cancer completely. But here's the thing. We
38:53
Speaker 1: may never get rid of it, but we can learn
38:55
Speaker 1: to live with it and keep it at bay. If
38:57
Speaker 1: we know that it can't survive without these two fuels
39:00
Speaker 1: and you can do a diet and lifestyle that can
39:03
Speaker 1: restrict the availability of those two fuels and keep your
39:05
Speaker 1: mitochondria as healthy as you possibly can.
39:08
Speaker 2: What if we don't go down that path? What do
39:09
Speaker 2: you think?
39:10
Speaker 1: Then you're going to be right. One out of two
39:11
Speaker 1: people are going to be having cancer. Your statistics are
39:14
Speaker 1: going to be absolutely correct.
39:17
Speaker 2: Is there anybody that you believe? Because, you know, when
39:19
Speaker 2: we talk about these subjects, often we think of like
39:21
Speaker 2: Big Pharma and the incentives and money and follow the
39:24
Speaker 2: money and you'll figure out why people don't want change.
39:26
Speaker 2: Is any of that sort of conspiratorial thinking correct in
39:30
Speaker 2: your view?
39:31
Speaker 1: I don't know if that's conspiracy. I don't like conspiracy terms.
39:34
Speaker 1: That's absurd. I like what are the facts of what
39:38
Speaker 1: we're looking at.
39:39
Speaker 2: But do you see a resistance from Big Pharma to
39:42
Speaker 2: entertain this point of view?
39:44
Speaker 1: What do you think? What do you think? I mean,
39:47
Speaker 1: do you think this is, I mean, you're making a
39:48
Speaker 1: lot of, not you, but But people in those industries,
39:51
Speaker 1: the hospital industry is making enormous amounts of money. They're
39:55
Speaker 1: awarding– we get $ 7 billion a year for cancer research
39:59
Speaker 1: in the National Cancer Institute, awarding many, many– not all,
40:03
Speaker 1: many grants to looking for gene mutations and all this
40:06
Speaker 1: kind of stuff. And we have drugs that are extremely
40:10
Speaker 1: expensive based on a somatic mutation theory of cancer that
40:13
Speaker 1: are basically not dropping the death rate. As I said,
40:16
Speaker 1: while we're talking here, we're going to have 140 people dead.
40:20
Speaker 1: from cancer. 1,700 people a year is getting worse and worse.
40:24
Speaker 1: As you said, we're always running for raising money for
40:27
Speaker 1: cancer research. Where's all that money going? What are you
40:30
Speaker 1: doing with all that money? No accountability. And then when
40:32
Speaker 1: you look at the scientific advisory committee of all these
40:35
Speaker 1: societies that you're running for, they all think publish papers
40:38
Speaker 1: on cancer as a genetic disease. It's too hard for
40:42
Speaker 1: the field to accept at this point. It's too traumatic.
40:48
Speaker 1: at what I'm saying. It's too disruptive to a massive
40:52
Speaker 1: industry at this time. They will come to gradually adjust
40:57
Speaker 1: to what I'm saying. It's just a matter of time
40:58
Speaker 1: because we cannot continue this trajectory. It's immoral what we're
41:03
Speaker 1: doing to some of these people.
41:04
Speaker 2: I read a stat that said the global incidence of
41:06
Speaker 2: early onset cancer increased by roughly 80% between 1990 and 2019.
41:10
Speaker 2: That's in the BMJ oncology.
41:11
Speaker 1: Mm-hmm.
41:16
Speaker 2: Early onset of cancer is basically patients under the age
41:18
Speaker 2: of 50. And when I think about this, you know,
41:20
Speaker 2: growing up in the UK, whenever there's a fun run,
41:23
Speaker 2: a charity race, a marathon, whatever it might be, cancer
41:26
Speaker 2: research gets the money. And to hear that, you know,
41:29
Speaker 2: there's been so much money invested in cancer research over
41:31
Speaker 2: the last couple of decades, but there's been an increase
41:34
Speaker 2: of 80% in early onset cancer in the same period.
41:38
Speaker 2: For me, I'm like, This research doesn't appear to be
41:42
Speaker 2: being very effective.
41:43
Speaker 1: Well, as I said, what people don't do is they
41:46
Speaker 1: never ask, where does the research go? What kind of research?
41:49
Speaker 1: What are you doing? What is the research? It's the
41:51
Speaker 1: theory that drives the impetus to do research.
41:55
Speaker 2: Now, a lot of great stuff has been done on
41:58
Speaker 2: keeping people alive that suffer from cancers, right? Because if
42:01
Speaker 2: you think about the probability of dying from a cancer,
42:04
Speaker 2: I'm assuming that has gone down.
42:07
Speaker 1: Yeah, to some extent it has. There's two ways of
42:10
Speaker 1: looking at it. It's called progression-free survival and overall survival.
42:14
Speaker 1: These are the terminologies that are used in the clinical
42:17
Speaker 1: world of cancer. And they represent the approval of drugs
42:20
Speaker 1: through the Food and Drug Administration. If you have a
42:23
Speaker 1: drug that improves progression-free survival, progression-free means it looks like
42:30
Speaker 1: the drug is working on the tumor. Because the tumor,
42:34
Speaker 1: you can see it. It gets bigger and bigger and
42:36
Speaker 1: more lethal and more lethal. And if I see it
42:38
Speaker 1: not growing nearly as much, I say, wow, look at that.
42:43
Speaker 1: It's slowing what we call traditional progression. It's called progression-free survival.
42:48
Speaker 1: And then you have overall survival. So you have two
42:52
Speaker 1: ways to approve drugs mostly for cancer, right? How does
42:56
Speaker 1: it work on progression-free survival? And how does it work
42:59
Speaker 1: on overall survival? Well, they stop looking at overall survival.
43:02
Speaker 1: Now somebody's going to bark and say, well, you know,
43:05
Speaker 1: bottom line is mostly progression-free, which means that the patients,
43:08
Speaker 1: it looks like the tumor is being effectively managed, but
43:11
Speaker 1: they live only a couple of months longer than they
43:14
Speaker 1: would have if they didn't use this drug. So therefore,
43:17
Speaker 1: it's approved. And that, as opposed to overall survival, you know,
43:22
Speaker 1: you're only living a two, okay, you've lived two and
43:24
Speaker 1: a half extra months. The tumor looked like it was
43:27
Speaker 1: managed pretty well, but your overall survival is this much
43:30
Speaker 1: but you didn't see the tumor growing, we're going to
43:33
Speaker 1: approve that drug. So a lot of the new drugs
43:36
Speaker 1: that we're giving do a really good job at progression-free survival,
43:39
Speaker 1: but they do a horrible job in keeping people alive
43:41
Speaker 1: much longer, which ultimately is what you want to do.
43:44
Speaker 1: You want overall survival. Let me give you an example, Avastin, Bevacizumab.
43:49
Speaker 1: This is an immoral drug that should never be used
43:51
Speaker 1: on people. It was blocked because it caused colon perforations
43:55
Speaker 1: in women with breast cancer. They still use it on
43:57
Speaker 1: brain cancer. And so in the tumor, you've got a tumor.
44:01
Speaker 1: You can see it with PET imaging. Not so much
44:05
Speaker 1: MRI and CAT scan. You can see it there. And
44:07
Speaker 1: it's looking there. Okay. You can see it. Now you
44:11
Speaker 1: give the patient Avastin, which is this anti-angiogenic drug. It's
44:17
Speaker 1: supposed to stop the abnormal blood vessels, right? They think
44:20
Speaker 1: that the angiogenesis blood vessels is driving the dysregulated growth.
44:25
Speaker 1: It's the fermentation that's driving the dysregulated growth, by the way.
44:29
Speaker 1: So all of a sudden, the tumor kind of disappears.
44:32
Speaker 1: It doesn't look like it. Whoa, patient gets all excited.
44:35
Speaker 1: The physician looks and says, look at that. Look at that.
44:38
Speaker 1: Looks like you're doing well. What the drug does is
44:41
Speaker 1: it causes the tumors to permeate your entire brain, like
44:47
Speaker 1: spreading it through your whole brain. You don't live any longer.
44:51
Speaker 1: But you had this progression free. Look at the tumor.
44:54
Speaker 1: So the patient gets excited because it looks like the
44:56
Speaker 1: tumor is disappearing with this very expensive drug. But what
45:00
Speaker 1: it does is it almost guarantees that that patient will
45:02
Speaker 1: not survive because you spread the tumor cells through the
45:04
Speaker 1: whole brain. So this is why I call it an
45:07
Speaker 1: immoral kind of a thing.
45:09
Speaker 2: But chemotherapy and sort of these radiation therapies, they have
45:13
Speaker 2: proven to keep people alive who otherwise would have died.
45:16
Speaker 1: In some cases, it can. And that's another thing we
45:20
Speaker 1: have to look at. I work heavily in brain tumors
45:23
Speaker 1: and glioblastomas and things like that. When you irradiate somebody's brain,
45:27
Speaker 1: who has one of these tumors, you free up massive
45:29
Speaker 1: amounts of glucose and glutamine in the microenvironment. And if
45:32
Speaker 1: you look at the survival, when we did survival, looked
45:35
Speaker 1: at survival curves for glioblastoma throughout the world, you can't
45:38
Speaker 1: even design experiments so consistent how fast people will die.
45:41
Speaker 1: It's like all the different hospitals have the same survival,
45:45
Speaker 1: same survival. What are you doing? Well, we do chemo.
45:47
Speaker 1: We do surgical debulking, temozolomide, and we give steroids, which
45:52
Speaker 1: raise blood sugar, and we irradiate. We irradiate. We irradiate.
45:55
Speaker 1: Everybody's dead. So not everybody, but five-year survival is very,
46:01
Speaker 1: very low. Ten-year survival is almost zero.
46:04
Speaker 2: But if you got a breast cancer or if you got.
46:07
Speaker 1: … This is brain cancer I'm talking about. Brain cancer, right.
46:09
Speaker 1: This is freeing up. Now, yes, if you have a
46:11
Speaker 1: circumscribed tumor and it's not anywhere else, you can come
46:15
Speaker 1: in with a radiation or surgical procedure and essentially cure
46:18
Speaker 1: that patient. But if you have any level of spread
46:21
Speaker 1: or anything like this, that person now … Also, if
46:26
Speaker 1: you're taking a toxic poison into your body, like red devil, doxorubicin,
46:31
Speaker 1: they call it red devil. Your pee turns red, everything
46:33
Speaker 1: turns red.
46:34
Speaker 2: What is that? Is that chemotherapy?
46:35
Speaker 1: Yes, it's a chemotherapy to kill a small group of
46:37
Speaker 1: cells or maybe a little bit of a spread. But
46:42
Speaker 1: your hair falls out, your body gets brutalized by this.
46:46
Speaker 1: And then if you survive the cancer, and many people do,
46:48
Speaker 1: we have millions and millions of cancer survivors on this planet.
46:52
Speaker 1: But many, many folks in that group suffer from the
46:55
Speaker 1: adverse effects of being poisoned or irradiated or surgically mutilated.
46:59
Speaker 1: I mean, they have to change their hold. And oftentimes
47:02
Speaker 1: the cancer comes back or they die from cardiovascular disease
47:05
Speaker 1: or they die from secondary adverse effects of being brutalized
47:10
Speaker 1: with medieval, I call it medieval, approaches to this. Are
47:13
Speaker 1: you kidding me what they're doing to cancer patients? So
47:17
Speaker 1: when we do metabolic therapy, we shrink the tumor down
47:21
Speaker 1: for sure. Then the surgeon can come in And he
47:24
Speaker 1: sees it's smaller, fewer blood vessels because of the metabolic therapy.
47:27
Speaker 1: And we can take out a greater amount of this.
47:30
Speaker 1: And then we transition back to prevent this tumor from recurring.
47:34
Speaker 1: Metabolic therapy can be used to not only prevent the cancer,
47:38
Speaker 1: but can also be used to treat the cancer. Most hospitals,
47:43
Speaker 1: most people say, well, I really want to do things
47:45
Speaker 1: to prevent cancer. Can I do standard of care before
47:48
Speaker 1: I have a tumor? What do you mean? You want
47:50
Speaker 1: to go into a major cancer clinic and have toxarubicin
47:55
Speaker 1: and radiation to your body just in the event that
47:57
Speaker 1: you might get a cancer? This is absurd. But yet
47:59
Speaker 1: when you have cancer, that's what they do to you, right?
48:02
Speaker 1: But with metabolic therapy, you can use it as both
48:04
Speaker 1: a prevention and a treatment. It's just that with the treatment,
48:07
Speaker 1: we bring in some more drugs to target the glutamine.
48:08
Speaker 1: We don't do that on the prevention side.
48:10
Speaker 2: On the... I was just looking at some stats as
48:12
Speaker 2: you were speaking around this five-year survival rates of a
48:15
Speaker 2: variety of different cancers over time. And... It does appear
48:20
Speaker 2: that survival rates of these cancers, from breast cancer, prostate cancer,
48:24
Speaker 2: to lung cancer, to leukemias and various melanomas, has improved
48:28
Speaker 2: since the 1970s. So the 1970s to the 1990s to 2010s,
48:34
Speaker 2: there's been an improvement in the survival rate, which I
48:37
Speaker 2: guess is a credit to the research that's been done.
48:40
Speaker 2: What you're saying is that the treatments we have still
48:43
Speaker 2: today are horrific.
48:45
Speaker 1: Yeah, and the survivals are not that much greater. It's
48:48
Speaker 1: not like you're getting massively longer survivals.
48:51
Speaker 2: Yeah, I mean, and I have to preface that these
48:53
Speaker 2: stats might not be right because this is AI we're
48:55
Speaker 2: dealing with here. But there's a 5%, for example, with
48:58
Speaker 2: breast cancer between the 1990s and 2010, there's just a
49:01
Speaker 2: 5% difference.
49:03
Speaker 1: In overall survival?
49:04
Speaker 2: In overall survival.
49:04
Speaker 1: Okay, so your survival, your overall survival is two and
49:07
Speaker 1: a half to three months greater.
49:08
Speaker 2: I don't actually have those stats.
49:11
Speaker 1: No, but that's the evidence, the papers that we're looking at.
49:15
Speaker 2: So how do we prevent this then? I'm 32 years
49:20
Speaker 2: old now. So I want to make sure that I
49:23
Speaker 2: live my life in such a way that I limit
49:24
Speaker 2: my chance of cancer. One of the things I always
49:26
Speaker 2: reflect on is the fact that many of the people
49:28
Speaker 2: that I know that have got cancer, breast cancer or
49:30
Speaker 2: other forms of cancer, appear to be remarkably healthy.
49:33
Speaker 1: Yeah, always at the beginning. Not always, but many times
49:38
Speaker 1: the person comes in and says, geez, I just was
49:39
Speaker 1: diagnosed with cancer. I didn't know I had it. I
49:41
Speaker 1: didn't feel bad. And then all of a sudden you
49:43
Speaker 1: get treated and they look like death warmed over.
49:45
Speaker 2: But I'm saying like how can healthy people be getting
49:48
Speaker 2: cancer if there's this sort of central … Well, because
49:50
Speaker 2: as I.
49:51
Speaker 1: Said, and we're seeing this. I'm seeing it in my own.
49:55
Speaker 1: I'm getting more and more emails from young people in
49:58
Speaker 1: their 30s, late 20s, 30s, early 40s, like with colon cancer,
50:02
Speaker 1: breast cancer and all these kinds of things. But look
50:04
Speaker 1: at our diet and lifestyle situation today. Those things that
50:08
Speaker 1: I'm talking about, lack of exercise, a lot of stress,
50:10
Speaker 1: poor sleep, bad food, all of this kind of stuff
50:13
Speaker 1: impacting parts of our bodies.
50:16
Speaker 2: So what do we do about it, though?
50:18
Speaker 1: Know about it.
50:19
Speaker 2: And then what do we do? So I know now.
50:21
Speaker 1: That's personal choice. I'm not here to take pieces and
50:23
Speaker 1: jelly donuts off the market, for sure, or breakfast cereal.
50:26
Speaker 1: I love that stuff, too. But the question is, I
50:29
Speaker 1: don't eat it every day. And I know if I do,
50:31
Speaker 1: it'll kill me. so so yeah skipping meals water only
50:39
Speaker 1: fat occasionally there's a lot of things you can do
50:41
Speaker 1: to keep your mitochondria healthy.
50:43
Speaker 2: Okay so tell me what those things are i just.
50:45
Speaker 1: Exercise you look like you're a pretty healthy guy yeah
50:47
Speaker 1: i go to the gym you don't look morbidly obese
50:49
Speaker 1: to me not yet not yet well that's important because
50:52
Speaker 1: you don't ever want.
50:53
Speaker 2: It yet we won't be in america too long so much.
50:55
Speaker 1: Yeah well and listen it's not just the united states
50:57
Speaker 1: we were kind of like the first ones to plow
50:59
Speaker 1: that field But it's starting to spread everywhere. I think
51:01
Speaker 1: in China, they have the most 200 million obese people
51:04
Speaker 1: in China now.
51:05
Speaker 2: So should I be on a keto diet then?
51:07
Speaker 1: Here's what we did. Okay. We developed the glucose ketone
51:11
Speaker 1: index calculator at Boston College. All right. My students and I,
51:14
Speaker 1: because we were trying to work with cancer patients, blood
51:18
Speaker 1: sugar and ketones independently of each other. And we had
51:23
Speaker 1: a ketone meter and we had a blood glucose meter.
51:25
Speaker 1: So we were monitoring ketones by itself. and glucose by itself.
51:30
Speaker 1: And we worked with a very nice woman from America
51:34
Speaker 1: who lived in Nice, France, who since passed away from
51:36
Speaker 1: a brain stem tumor. It was very, very difficult. We
51:38
Speaker 1: kept her alive very long, but eventually we didn't know
51:41
Speaker 1: what we know now. But she got into an argument
51:45
Speaker 1: for a handicapped parking spot with her neighbor upstairs and
51:49
Speaker 1: her blood sugar went through the roof. She ran upstairs
51:51
Speaker 1: and she took her blood sugar and And she says,
51:54
Speaker 1: oh my God, the tumor is going to grow. I said,
51:55
Speaker 1: what's your ketones? And she says, oh, it's still two
51:57
Speaker 1: and a half millimolar. Well, that's still pretty high. Usually
52:00
Speaker 1: it's very, very low. It's very high. So my students
52:04
Speaker 1: and I, we said, you know, this is too traumatic
52:06
Speaker 1: to try to measure these two independently. Why don't we
52:09
Speaker 1: make a singular number, divide the glucose in millimolar in
52:12
Speaker 1: the blood by the ketone in millimolar in the blood.
52:15
Speaker 1: Now you get this number that's much more stable. And
52:18
Speaker 1: it allows the cancer patient to know that if I
52:21
Speaker 1: keep this zone at 2.0 and below, my tumor cells
52:24
Speaker 1: aren't going to be able to grow very fast. I
52:26
Speaker 1: did this for the brain cancer, right? Now it's being
52:28
Speaker 1: used for all cancers. And now it's being used for
52:31
Speaker 1: guys like yourself who just want to stay healthy. Because
52:34
Speaker 1: what it is essentially is a quantitative determination if you're
52:37
Speaker 1: in the paleolithic zone or not. Oh, so if I'm
52:40
Speaker 1: at 2.0, like my friend Dominic D'Agostino, he's always down
52:44
Speaker 1: in these zones. He's a paleolithic man living in modern society.
52:48
Speaker 2: What's a Paleolithic man?
52:49
Speaker 1: That's how our ancestors were during the Paleolithic period.
52:53
Speaker 2: Okay, so he's got the right balance of glucose and ketones.
52:55
Speaker 1: Like we did when we were hunting mammoths and buffaloes
52:59
Speaker 1: and these kinds of things. When we were hunter-gatherers and
53:02
Speaker 1: the thousands of years of our existence as a species,
53:05
Speaker 1: tens of thousands of years, he is in that zone.
53:08
Speaker 2: Is he in keto?
53:09
Speaker 1: Yeah, well, that's what the low GKI is. That means
53:13
Speaker 1: you're at a level of keto. Yes, he doesn't eat
53:16
Speaker 1: a lot of carbohydrates in his diet. So it's leafy
53:18
Speaker 1: vegetables and a lot of meat and this kind of thing.
53:21
Speaker 1: Sparingly on fruits, like grapefruits, we learn from the epilepsy field,
53:26
Speaker 1: grapefruits provide a tremendous amount of vitamin C and do
53:29
Speaker 1: not spike glucose. That's very interesting. So you can have
53:33
Speaker 1: certain fruits that can keep you in this metabolic zone.
53:37
Speaker 1: I call it the paleolithic zone, which is the way
53:39
Speaker 1: we evolved when there was no cancer. in our, in
53:41
Speaker 1: our existence.
53:42
Speaker 2: When people hear that, they might start jumping on the
53:43
Speaker 2: paleo diet. I don't even know what the paleo diet is.
53:45
Speaker 1: Not a paleo diet. It's, it's diets that are low
53:47
Speaker 1: in carbohydrates. Okay.
53:49
Speaker 2: Okay.
53:50
Speaker 1: Um, Mediterranean diets. Like people say to me, what should
53:53
Speaker 1: I eat? Should I eat this and that? Normally you
53:55
Speaker 1: would eat foods that have very low, low glycemic index,
53:59
Speaker 1: which means the speed with which glucose is released like
54:01
Speaker 1: a banana, very high in glycemic index. You eat a banana,
54:05
Speaker 1: your blood sugar immediately spikes. Many fruits are like that. Um,
54:09
Speaker 1: But you want foods that keep a low steady GKI. Now,
54:14
Speaker 1: I built that calculator for brain cancer patients initially. Then
54:20
Speaker 1: we realized it's powerful for all cancers. We put the
54:23
Speaker 1: cancer patient in the low glucose ketone index. We get
54:27
Speaker 1: them down in there. Then we come in with the
54:28
Speaker 1: glutamine targeting drugs to kind of polish off these tumors
54:31
Speaker 1: or put them in even a more dormant state. But
54:34
Speaker 1: now we're finding all these young kids, like yourself, all
54:36
Speaker 1: these 30, 20-year-olds with the GKI. I mean, they're out
54:40
Speaker 1: to weightlifting and they're looking at their G. They don't
54:41
Speaker 1: have cancer. They're just excited to see if they can
54:44
Speaker 1: get into this paleolithic zone by themselves. And yes, that
54:47
Speaker 1: will prevent cancer because you can't get cancer if you're
54:50
Speaker 1: mitochondrial healthy. If you're in a paleolithic zone where our
54:53
Speaker 1: ancestors rarely have ever got cancer, then you're back in this, oh,
54:56
Speaker 1: you mean to tell me I can't eat this and
54:58
Speaker 1: I can't eat that? What does it do to your GKI? Oh,
55:00
Speaker 1: it makes it go up. Well, don't eat that.
55:03
Speaker 2: So you did a study on dogs, a dog with
55:05
Speaker 2: a tumor. Yes. Can you tell me about that study?
55:08
Speaker 1: It was a woman came to me. And this is
55:11
Speaker 1: what I say. You don't have to have a PhD
55:14
Speaker 1: in biochemistry to understand some of the things. This woman
55:18
Speaker 1: had no degree whatsoever. She just heard about what we
55:22
Speaker 1: did to these mice. And she did the same thing
55:25
Speaker 1: to her dog. It was a pit bull. And at
55:28
Speaker 1: age seven years old, it had a big mast cell
55:30
Speaker 1: tumor on its lip. So she listened to my YouTube
55:33
Speaker 1: video over and over. She said to me, I just
55:35
Speaker 1: kept listening. She says, I got some raw chicken. She
55:41
Speaker 1: says dogs, wolves evolved to eat chickens. So she got
55:44
Speaker 1: some chicken, chopped up the chicken. She cut the calories.
55:48
Speaker 1: She found some dog food calculator to how much calories
55:51
Speaker 1: the dog was getting. She cut the calories. The dog
55:54
Speaker 1: lost only 5% of its body weight. She got fish oil,
55:59
Speaker 1: raw eggs. And cut all the calories. Everything was all
56:03
Speaker 1: natural for this dog. And all of a sudden, we
56:06
Speaker 1: have the pictures. You can see them if you saw
56:08
Speaker 1: the picture. Big tumor on its lip. The veterinarian said,
56:13
Speaker 1: this dog is going to survive. You have to give
56:15
Speaker 1: him chemo and radiation and surgery and all this kind
56:17
Speaker 1: of stuff. And it's going to cost a lot of money.
56:19
Speaker 1: The dog's going to have diarrhea. She didn't want any
56:21
Speaker 1: part of that. So she said, well, let's just try
56:24
Speaker 1: this metabolic thing. And she's kept all the records and
56:28
Speaker 1: the pictures and what she did and how much she
56:30
Speaker 1: gave the dog and all this. So I was able
56:31
Speaker 1: to get all that information from her, put my friend
56:35
Speaker 1: Lauren Nations, who is a veterinarian, on the paper because
56:40
Speaker 1: I said, what, biology guy at Boston College is telling
56:42
Speaker 1: you how to manage cancer in a dog. We got
56:44
Speaker 1: to have some veterinarian on here to validate to make
56:47
Speaker 1: sure he's there. And he looked at the pictures and
56:49
Speaker 1: we looked at all the things. It disappeared. So what happened?
56:52
Speaker 1: was the dog eventually died of heart disease at 15
56:55
Speaker 1: and a half years of age. So essentially, that's the only,
56:59
Speaker 1: when people say, well, metabolic therapy cure cancer, I say
57:03
Speaker 1: metabolic therapy is never considered a cure for cancer. It's
57:07
Speaker 1: an effective non-toxic management for cancer. But in the case
57:10
Speaker 1: of that dog, it appeared to work, it's a cure
57:12
Speaker 1: for the dog. But that's the only one I'll say, oh,
57:14
Speaker 1: he's going to say a cure cannot. That dog happened
57:16
Speaker 1: to get, he died from old age from a heart attack.
57:19
Speaker 1: And we did it with a brain tumor guy, Pablo Kelly,
57:21
Speaker 1: who just passed away, unfortunately, from a surgical. He had
57:26
Speaker 1: a major cerebral hemorrhage after his surgery from Devon, England.
57:31
Speaker 1: You know Devon, England?
57:32
Speaker 2: That's where I'm from.
57:32
Speaker 1: Are you from Devon?
57:33
Speaker 2: Yeah.
57:34
Speaker 1: Oh, wow. Well, Pablo was there. He just passed away, fortunately.
57:36
Speaker 1: We were talking to him the day before he passed away.
57:39
Speaker 2: Pablo.
57:39
Speaker 1: Pablo Kelly. So he was from Devon, England, had a glioblastoma,
57:44
Speaker 1: which is the worst of the worst. They said, and
57:47
Speaker 1: he's all over your newspapers there in Devon. He was
57:49
Speaker 1: always sending me articles from England. Man rejects standard of care.
57:55
Speaker 1: So he had this glioblastoma and they took the tissue out.
57:59
Speaker 2: Which is brain cancer.
58:00
Speaker 1: Yeah, brain, the worst of the brain cancers. They took
58:03
Speaker 1: the tumor out and they said, oh, it's inoperable, inoperable.
58:09
Speaker 1: But if you do radiation and chemo, you might live nine,
58:14
Speaker 1: maybe 12 months at the most. Well, Pablo came from
58:17
Speaker 1: a family of like, we don't dabble in this kind
58:20
Speaker 1: of medicine. We're more holistic kind of people. So he
58:23
Speaker 1: emailed me, this was in 2014, and said, I want
58:27
Speaker 1: to try this metabolic thing. So he rejected chemo and radiation.
58:34
Speaker 1: And they said it wasn't surgically capable of being completely
58:37
Speaker 1: removed anyway. So he did this I gave him the
58:41
Speaker 1: information that I give to everybody. And this was way
58:44
Speaker 1: back before we knew a lot of what we now know.
58:47
Speaker 1: And I said, this poor guy, he doesn't want. And
58:50
Speaker 1: they said, you're going to be dead. They browbeat him.
58:52
Speaker 1: They try to force him to put that radiation mask on.
58:55
Speaker 1: They hacked his beard off, all this kind of stuff.
58:58
Speaker 1: And he just jumped up. He said, I can't do
58:59
Speaker 1: this stuff. So he didn't take any steroids. He didn't
59:02
Speaker 1: take any radiation. He didn't take any chemo. He just
59:06
Speaker 1: did the metabolic therapy. And he's on English things with
59:09
Speaker 1: all of his paleo diet, which is actually a very
59:12
Speaker 1: low-carbohydrate diet. He had the avocados there. He had the
59:15
Speaker 1: fish oil there. He had this different stuff. Two or
59:18
Speaker 1: three years go by. He emails me. I said, geez, Pablo,
59:22
Speaker 1: I thought you would have been dead. You're still alive?
59:24
Speaker 1: What's going on with that? So he calls me up
59:29
Speaker 1: and he says, you know, I went in for a
59:31
Speaker 1: CAT scan. The doctors are like still surprised that he's alive.
59:35
Speaker 1: And they said, this tumor is still there and it's growing.
59:39
Speaker 1: And they think they can cut it out now. So
59:41
Speaker 1: he was three years on just metabolic approach. He didn't
59:45
Speaker 1: take any glutamine inhibitors, which was really remarkable. So anyway,
59:49
Speaker 1: he asked me, and I have physician friends that are
59:53
Speaker 1: radiologists that can look at it. We measured it when
59:55
Speaker 1: it was first First diagnosed in 2014. And then we
59:59
Speaker 1: saw it did become a little bigger. And now the
1:00:02
Speaker 1: surgeon said, I think I can get it. It looks
1:00:04
Speaker 1: more resectable. Here it was inoperable. Now it becomes resectable.
1:00:08
Speaker 1: So he took it out. And Pablo recovered really well.
1:00:13
Speaker 1: And the surgeon says, I think I got it all. Wow.
1:00:17
Speaker 1: And Pablo is measuring his glucose ketone index with our
1:00:21
Speaker 1: ketone monitor. So I had every day, sometimes two and three.
1:00:24
Speaker 1: Five years of data on Pablo Kelly. Can you believe this?
1:00:28
Speaker 1: So anyway, Pablo thinks he's cured because the surgeon, all
1:00:32
Speaker 1: of a sudden he goes back to his kind of
1:00:34
Speaker 1: weak ways. And you can see that his GKI goes up.
1:00:38
Speaker 1: And all of a sudden the tumor starts to show
1:00:40
Speaker 1: up again. Puts the fear of God back into him.
1:00:43
Speaker 1: Goes back on a more restrict condition. Another three years
1:00:47
Speaker 1: goes by. And this time the tumor is growing slowly,
1:00:50
Speaker 1: very slowly. Don't forget, glioblastomas kill you very quickly. So
1:00:54
Speaker 1: with standard of care, you can barely get out of–
1:00:56
Speaker 1: at his age, if you can get two years, you're
1:00:58
Speaker 1: doing really good. So anyway, now he's three and he's
1:01:01
Speaker 1: got six years out. And he says, you know, it's
1:01:06
Speaker 1: still back. I got to go in. So this is
1:01:09
Speaker 1: second debulking. First debulking goes off, gets back on. Another
1:01:12
Speaker 1: second debulking. Another three years goes by, he has a
1:01:15
Speaker 1: third debulking. Can you believe this?
1:01:16
Speaker 2: What's a debulking?
1:01:17
Speaker 1: A debulking is the cutting the tumor out. It's the
1:01:20
Speaker 1: surgical removal of this tumor. But he's never had radiation
1:01:24
Speaker 1: or chemo or any of the kinds of what we
1:01:25
Speaker 1: call standards of care. And now he has– I talked
1:01:32
Speaker 1: to him a couple of weeks ago and he was
1:01:35
Speaker 1: doing really, really good. He had the third removal and
1:01:39
Speaker 1: we were laughing with myself and Dr. Duryea and my associates.
1:01:44
Speaker 1: He says, yeah, can you imagine? I've had now three
1:01:48
Speaker 1: operations on a previously inoperable tumor. What? So we were saying, wow,
1:01:55
Speaker 1: they got that one wrong. Didn't they, Pablo? And they
1:01:57
Speaker 1: kept wanting to irradiate him and do all this stuff.
1:01:59
Speaker 1: And he said, no, no, I'm going to keep doing this.
1:02:01
Speaker 1: And so we were speaking to him. And he's now
1:02:05
Speaker 1: 10 years. The tumor was diagnosed in August 2014. And
1:02:11
Speaker 1: he passed away August 2024. They tried to go in
1:02:16
Speaker 1: and get the last bit of tumor out of his brain.
1:02:18
Speaker 1: We got him We talked to him. Thumbs up, smiling,
1:02:23
Speaker 1: talking like crazy. Six hours later, cerebral hemorrhage and he dies.
1:02:26
Speaker 1: So he didn't die from the cancer. He died from
1:02:29
Speaker 1: a surgical problem with the surgery. So he was– you
1:02:33
Speaker 1: talk about long-term survivors. You rarely survive cancer. two years
1:02:38
Speaker 1: with a glioblastoma, the fact that he was out 10 years.
1:02:41
Speaker 1: And if he hadn't had that last bit of surgery,
1:02:43
Speaker 1: the guy would have still been alive because he was
1:02:45
Speaker 1: talking like you and I are talking. This is a
1:02:46
Speaker 1: guy who has a terminal. So I said to Pablo,
1:02:50
Speaker 1: I said, you could outlive me. I said, we're all
1:02:53
Speaker 1: terminal to some extent, right? We're never, all of us
1:02:55
Speaker 1: aren't going to live to that. I said, he was
1:02:57
Speaker 1: a young guy. He was only 22 or 23 when
1:02:59
Speaker 1: he was diagnosed. He was in his 30s now when
1:03:01
Speaker 1: he passed away, 10 years. So he's 33, 34 years old.
1:03:06
Speaker 1: And I said, you know, I could be dead before you.
1:03:08
Speaker 1: And we were laughing. We had a good time. And
1:03:10
Speaker 1: the next thing I know, I get an email from
1:03:11
Speaker 1: his wife. He said, Pablo is brain dead or something.
1:03:17
Speaker 1: I said, what the hell happened? What happened to this
1:03:20
Speaker 1: poor guy? And it wasn't the cancer. So I don't
1:03:24
Speaker 1: know how long he would have lived, how many more things.
1:03:27
Speaker 1: But what I'm saying, oh, he's an anecdote. Well, listen,
1:03:30
Speaker 1: if I had a drug that did what metabolic therapy
1:03:33
Speaker 1: did and I could get more people like Pablo, are
1:03:35
Speaker 1: you kidding me? they'd be running all over the world.
1:03:38
Speaker 2: And when you say metabolic therapy, you mean the combination
1:03:41
Speaker 2: of the calorie restrictive ketogenic approach?
1:03:44
Speaker 1: Yes.
1:03:45
Speaker 2: Yeah.
1:03:45
Speaker 1: Avoiding. Well, first of all, you're avoiding, you're avoiding things
1:03:47
Speaker 1: that are going to kill you. The radiation is going
1:03:49
Speaker 1: to kill you for the, for many people, not all people. Okay.
1:03:52
Speaker 1: Everybody said, well, listen, you can, you can look at the,
1:03:54
Speaker 1: go have people look at the data themselves for crying
1:03:56
Speaker 1: out loud and you can see how long you're going
1:03:58
Speaker 1: to live. He didn't do what they, what they grab
1:04:00
Speaker 1: everybody in.
1:04:01
Speaker 2: What did he do specifically?
1:04:02
Speaker 1: He didn't take radiation or chemo and he, brought his
1:04:05
Speaker 1: glucose ketone index down to the 2.0 zone and kept
1:04:09
Speaker 1: it low. And he took some supplements and a few
1:04:12
Speaker 1: things here and there, but he wasn't really targeting the
1:04:15
Speaker 1: glutamine like we found now certain parasite medications will be
1:04:20
Speaker 1: effective in targeting glutamine. So we're doing all non-toxic strategies
1:04:24
Speaker 1: to manage cancer. You don't have to be brutalized by
1:04:27
Speaker 1: the system if you know what to do and how
1:04:29
Speaker 1: to do it. The problem is most of the poor
1:04:31
Speaker 1: oncologists never heard of what I'm talking about. The stuff
1:04:33
Speaker 1: I'm telling you right now, they never heard of it.
1:04:35
Speaker 2: The risk is someone gets cancer that's listening to this
1:04:37
Speaker 2: or someone has cancer that's listening to this. I mean, statistically,
1:04:40
Speaker 2: there's a lot of people listening to this that have
1:04:41
Speaker 2: cancer right now. And they're speaking to their doctor. And
1:04:44
Speaker 2: their doctor is saying, chemotherapy, radiation therapy, et cetera.
1:04:48
Speaker 1: Et cetera. And glucose has nothing to do with the tumor.
1:04:50
Speaker 1: Eat whatever you want.
1:04:52
Speaker 2: Yeah. And so what do you say to those people
1:04:54
Speaker 2: who they've just got a diagnosis and their doctors are saying, right, listen,
1:04:59
Speaker 2: this is pretty severe. We're going to suggest that you
1:05:01
Speaker 2: take chemotherapy.
1:05:02
Speaker 1: Yeah.
1:05:03
Speaker 2: You're not telling them not to take chemotherapy, are you?
1:05:05
Speaker 1: I'm not telling them that. And what we found is
1:05:08
Speaker 1: that when you are in nutritional ketosis with a glucose
1:05:12
Speaker 1: ketone index of 2.0 or below, my colleagues that we
1:05:16
Speaker 1: work with in Istanbul, Turkey, were able to show that
1:05:18
Speaker 1: chemotherapies at much lower dosages can be even more therapeutically
1:05:22
Speaker 1: powerful when you're in nutritional ketosis. So you don't have
1:05:26
Speaker 1: to get rid of a lot of these different procedures
1:05:28
Speaker 1: that we have today. I'm just saying radiation for brain cancer.
1:05:31
Speaker 1: I'm not saying radiation for lung or some of the
1:05:33
Speaker 1: other cancers. Because if you can shrink those tumors down
1:05:37
Speaker 1: and make them very weak and vulnerable, a surgical procedure,
1:05:40
Speaker 1: a radiation procedure, even low-dose chemo could come in. And
1:05:44
Speaker 1: even immunotherapy, if you took a big tumor and shrunk
1:05:47
Speaker 1: it down to a small nub and it's resistant to
1:05:50
Speaker 1: a lot of the things, they all have to share
1:05:53
Speaker 1: something in common for them to survive this path. that
1:05:57
Speaker 1: might be an immunotherapy could come in because they're gonna
1:06:00
Speaker 1: target whatever all of them have together and you could
1:06:02
Speaker 1: possibly get rid of it that way.
1:06:04
Speaker 2: I'm thinking of a friend of mine that has been
1:06:06
Speaker 2: diagnosed with brain cancer, brain tumor. And this is one
1:06:10
Speaker 2: of the most, you know, it's a woman in her
1:06:13
Speaker 2: 40s or 50s, trying to keep her anonymous as possible,
1:06:17
Speaker 2: who is just the most fit athletic person that I know,
1:06:22
Speaker 2: eats amazingly well, is literally known for exercise. And I'd go, how?
1:06:28
Speaker 2: How is it possible that someone who I would probably
1:06:30
Speaker 2: say is fitter than I am, if you looked at
1:06:32
Speaker 2: their sort of metabolic health, has got a severe brain tumor?
1:06:36
Speaker 1: Well, they can stay healthy for, and I'm not saying
1:06:41
Speaker 1: everybody who has, and it depends on what kind of
1:06:43
Speaker 1: a tumor it is as well. Is it a glioblastoma, oligodendroglioma,
1:06:47
Speaker 1: you know, peanut, there's a lot of different kinds of tumors.
1:06:50
Speaker 2: Well, I know that it's not growing necessarily, but it's
1:06:53
Speaker 2: big and it's in the brain and they're going to
1:06:55
Speaker 2: remove it for a surgical operation.
1:06:57
Speaker 1: Well, if they can, what we always suggest for the
1:06:59
Speaker 1: brain cancer, if you do metabolic therapy up front, and
1:07:02
Speaker 1: I've had surgeons tell me this, you can shrink it
1:07:05
Speaker 1: down because one of the, it's angry, it's an angry thing, right?
1:07:10
Speaker 1: And you can see some slight invasion. If you can
1:07:13
Speaker 1: shrink that down so that it's more circumscribed, now the
1:07:17
Speaker 1: surgeon can look at it and go, oh my God.
1:07:19
Speaker 1: We know many, many scientific publications, the more you can debulk,
1:07:23
Speaker 1: that's called the removal of the tumor, debulking, the longer
1:07:27
Speaker 1: the patient will survive. The evidence is massive to support that. But,
1:07:30
Speaker 1: you know, with a lot of these brain tumors, you
1:07:32
Speaker 1: don't get it all. And there's always some little piece
1:07:34
Speaker 1: that remains. And when you irradiate, you explode the ability
1:07:37
Speaker 1: of the cells to ferment energy and it's very hard
1:07:40
Speaker 1: to kill them. But if you can get the majority
1:07:43
Speaker 1: of it out and then transition the patient back into
1:07:46
Speaker 1: a metabolic state, keeping the pressure on those tumor cells,
1:07:49
Speaker 1: you can remain healthy like Pablo. I mean, these guys can.
1:07:52
Speaker 2: And when you found in mice is that when ketogenic
1:07:54
Speaker 2: diet was combined with a hyperbaric oxygen therapy, the average
1:07:57
Speaker 2: survival time was increased by roughly 80%.
1:08:00
Speaker 1: Yeah, even more sometimes now. But okay, so why do
1:08:04
Speaker 1: we do hyperbaric oxygen, right? That's the question. What's going
1:08:08
Speaker 1: on with hyperbaric oxygen? Why is this like a good thing?
1:08:13
Speaker 1: It works best when the patient and the mouse is
1:08:15
Speaker 1: in nutritional ketosis. Okay, so look, we have a tumor.
1:08:20
Speaker 1: We irradiate that tumor. How does the radiation kill the
1:08:23
Speaker 1: tumor cells? It hits oxygen, blows up, and it causes
1:08:26
Speaker 1: a reactive ROS, and it's like stepping on a landmine.
1:08:31
Speaker 1: It blows the tumor up, right? So cancer cells protect themselves,
1:08:36
Speaker 1: even though they make a lot of rust. They're this
1:08:39
Speaker 1: close to death anyway. But they have a very powerful
1:08:43
Speaker 1: antioxidant system. And interestingly enough, That besides causing the dysregulated growth,
1:08:50
Speaker 1: the glucose and the glutamine also protect them to some
1:08:53
Speaker 1: extent from the ROS that they're making. Can you believe this?
1:08:56
Speaker 2: The ROS.
1:08:57
Speaker 1: ROS. ROS. Reactive oxygen. species that are carcinogenic and mutagenic.
1:09:03
Speaker 1: So they destroy our proteins, lipids, and nucleic acids. They're
1:09:09
Speaker 1: disruptive molecules. So radiation will cause a ROS in the microenvironment, ROS,
1:09:15
Speaker 1: that'll blow up and kill cells, normal and tumor cells.
1:09:19
Speaker 1: But if you want to selectively kill tumor cells with ROS,
1:09:23
Speaker 1: not to cause your hair to fall out, your gums
1:09:26
Speaker 1: to bleed, and all this crazy stuff, you take the patient,
1:09:29
Speaker 1: you put him in nutritional ketosis, and you say he's
1:09:32
Speaker 1: got low GKI. Then you go into hyperbaric oxygen, which
1:09:35
Speaker 1: dissolves oxygen directly into your blood now. It's better than
1:09:38
Speaker 1: just breathing 100% oxygen because you can actually dissolve oxygen
1:09:41
Speaker 1: in the bloodstream. then you're taking away the two fuels
1:09:46
Speaker 1: that protect the tumor and you're giving it internal ROS,
1:09:49
Speaker 1: which kills the tumor internally, only to the tumor cell,
1:09:52
Speaker 1: not to your surrounding tissues. So you're killing, selectively killing
1:09:56
Speaker 1: tumor cells without collateral damage to the rest of your body.
1:09:59
Speaker 1: As a matter of fact, the rest of your cells
1:10:01
Speaker 1: are getting super healthy because they're burning ketones and pure oxygen. Unbelievable.
1:10:05
Speaker 2: How do we measure for.
1:10:06
Speaker 1: Can you believe this? I can't even believe I'm saying
1:10:08
Speaker 1: this stuff myself.
1:10:09
Speaker 2: Yeah.
1:10:11
Speaker 1: You really got to know the biochemistry. And you have
1:10:13
Speaker 1: to know the physiology of your own body. And you
1:10:15
Speaker 1: have to understand evolutionary biology.
1:10:17
Speaker 2: Most people just aren't that intelligent, including me.
1:10:20
Speaker 1: It's not intelligence.
1:10:22
Speaker 2: Most people kind of want things, sort of simple principles
1:10:27
Speaker 2: that they can live by.
1:10:28
Speaker 1: And also quick and easy.
1:10:30
Speaker 2: Yeah, of course.
1:10:30
Speaker 1: Okay. They don't want to do what I'm talking about it.
1:10:33
Speaker 1: Because it might be, oh, the other thing, let me
1:10:35
Speaker 1: tell you one thing and remember it. If you do
1:10:37
Speaker 1: metabolic therapy, success rides heavily on your shoulders. You're not
1:10:41
Speaker 1: sitting there like some manikin, some guy's poisoning and irradiating you.
1:10:45
Speaker 1: To make metabolic therapy work, you are the one doing
1:10:48
Speaker 1: the GKI. You're the one, it's your soul. You're responsible
1:10:53
Speaker 1: for your existence on this planet. You're going to put
1:10:55
Speaker 1: your precious soul in the hands of someone who has
1:10:59
Speaker 1: less of a knowledge about the problem than you might.
1:11:03
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1:11:54
Speaker 2: The link is in the description below. Could you be
1:11:57
Speaker 2: predisposed genetically to cancer?
1:11:59
Speaker 1: Yeah, that's where those germline mutations, but you can manage that.
1:12:02
Speaker 2: Because people think, you know, my grandmother had breast cancer,
1:12:05
Speaker 2: my mother had breast cancer. So, you know.
1:12:07
Speaker 1: They live in a common environment too. It's not like you're, like,
1:12:10
Speaker 1: you know, to prove that you and all the siblings
1:12:12
Speaker 1: would have to be raised in a different environment, different countries,
1:12:16
Speaker 1: different lifestyles. And then see if you all got cancer
1:12:18
Speaker 1: at the same time under all these different conditions, that's
1:12:20
Speaker 1: definitely genetic. That's like Huntington's disease, Tay-Sachs disease or these
1:12:24
Speaker 1: kinds of things. where they'll manifest regardless of the environment.
1:12:27
Speaker 2: So are you saying to me that I should, as
1:12:29
Speaker 2: a 32-year-old man that's cancer-free, God willing, I think, touch wood,
1:12:34
Speaker 2: I should calorie restrict myself to keep my mitochondria healthy
1:12:38
Speaker 2: and my metabolism healthy now? I should be in a
1:12:44
Speaker 2: sort of calorie restricted state?
1:12:45
Speaker 1: I say it's good to visit the state. Our Paleolithic
1:12:48
Speaker 1: ancestors had no choice. There wasn't a donut shop on
1:12:52
Speaker 1: every corner. There wasn't pizzas. There weren't the kinds of
1:12:55
Speaker 1: highly processed carbohydrate foods available to them.
1:12:58
Speaker 2: So should I be fasting? Should I be doing keto?
1:13:00
Speaker 1: You know, I don't want to tell you what you
1:13:02
Speaker 1: should or should not do. I'm not a physician here.
1:13:04
Speaker 1: I'm a scientist. I study what causes these things and
1:13:07
Speaker 1: I study how to manage them. You have to read
1:13:09
Speaker 1: what I'm saying and you have to come to your
1:13:12
Speaker 1: own decisions about how you want to conduct your life.
1:13:15
Speaker 1: I've given you information.
1:13:16
Speaker 2: What's your view on fasting?
1:13:18
Speaker 1: Fasting is a powerful way to get your body into
1:13:21
Speaker 1: nutritional ketosis, but it ain't easy. Try doing it. You
1:13:25
Speaker 1: try doing it. See how easy it is. It ain't easy, right?
1:13:29
Speaker 1: But that's why we developed this procedure where if you go,
1:13:33
Speaker 1: rather than going cold turkey and say, well, today I'm
1:13:36
Speaker 1: going to have a big, I'm going to eat as
1:13:37
Speaker 1: much as I can, and then tomorrow, okay, you can
1:13:39
Speaker 1: go tomorrow. It's the second, third days when you start
1:13:42
Speaker 1: to really know what the hell is going on. Believe me,
1:13:44
Speaker 1: I've tried it. It ain't easy. That's why we developed it.
1:13:48
Speaker 1: a zero-carb diet for 14 days, 10 to 14 days,
1:13:51
Speaker 1: just zero. You eat meat, fish, chicken, whatever you want,
1:13:54
Speaker 1: but just don't eat any bread, pasta, this kind of thing.
1:13:57
Speaker 2: On keto, how do we get into that sort of
1:14:00
Speaker 2: ketosis state that people often talk about?
1:14:02
Speaker 1: Measure your glucose ketone index. How do I do that?
1:14:05
Speaker 1: With the Keto Mojo meter. You can buy it from Amazon. Okay. Okay,
1:14:09
Speaker 1: you can buy it. Now, don't forget they get a
1:14:11
Speaker 1: free Libra meter now for the blood. They're working on
1:14:13
Speaker 1: ketone blood meters, but it's not there yet. Right now,
1:14:16
Speaker 1: the Keto-Mojo or some other Keto meters where you can
1:14:20
Speaker 1: prick your finger like a diabetic. You take a glucose
1:14:22
Speaker 1: strip and you put it on the blood and you
1:14:24
Speaker 1: put it into the machine. It tells you what your
1:14:25
Speaker 1: glucose is. Squeeze your finger a little bit more. Take
1:14:28
Speaker 1: the ketone strip, touch it to the blood, put it
1:14:30
Speaker 1: in the meter. It gives you the ketone value. Push
1:14:33
Speaker 1: the button. GKI comes right up. Okay. Okay. Very simple.
1:14:37
Speaker 1: Everybody can buy it from Amazon. Get the meter. Buy
1:14:40
Speaker 1: the consumables. And then they can test it. This is
1:14:43
Speaker 1: what Pablo, this is what all the cancer patients, the
1:14:45
Speaker 1: ones who really want to get into metabolic ketosis.
1:14:48
Speaker 2: I think I've tried keto before. And I say think
1:14:50
Speaker 2: because I didn't measure my keto levels. I was assuming
1:14:53
Speaker 2: I did.
1:14:53
Speaker 1: Yeah. No, it's really people say, well, I haven't eaten.
1:14:56
Speaker 1: I'm in keto. How do you know? Well, I blew
1:14:58
Speaker 1: into this thing and the bulb came on. I peed
1:14:59
Speaker 1: on a strip. It looked like it was ketosis. They
1:15:02
Speaker 1: are indirect measures. The most accurate is the blood measure.
1:15:05
Speaker 2: It's hard to stay in that state. For most people, right?
1:15:09
Speaker 2: This is one of the things I hear.
1:15:10
Speaker 1: Because the temptations in our society are so strong. Yeah.
1:15:14
Speaker 1: I mean, Paleolithic man had no choice. Do you think
1:15:16
Speaker 1: he– that was his state. That's all he knew for
1:15:19
Speaker 1: thousands and thousands, tens of thousands, hundreds of thousands of years.
1:15:23
Speaker 1: That's all he knew. He didn't say, oh, let me
1:15:25
Speaker 1: go down to get a big jelly-filled donut down at
1:15:28
Speaker 1: the end of the river there. No, there's none of that.
1:15:30
Speaker 1: He had to live in that state. Now we have
1:15:33
Speaker 1: so many temptations. All the things that we are biologically
1:15:36
Speaker 1: clear for. When you see obesity, that's evolution in action.
1:15:41
Speaker 1: They are the descendants of our long ancestors that could
1:15:45
Speaker 1: hold on to energy so efficiently. We were an energy-starved
1:15:49
Speaker 1: species for the majority of our existence on the planet.
1:15:52
Speaker 1: So anything we ate would be very little waste. We
1:15:55
Speaker 1: never pee out glucose. Glucose is converted to fat, and
1:15:57
Speaker 1: we store energy as fat. So those guys are energy-efficient
1:16:02
Speaker 1: human beings. Now, all of a sudden, we find ourselves
1:16:05
Speaker 1: with everything. And boom! That's evolution in action, man. You're
1:16:10
Speaker 1: allowing to see how we can store energy so efficiently
1:16:15
Speaker 1: because our ancestors lived through such environmental forcing. We had famines.
1:16:21
Speaker 1: We had long treks. Our body could store energy so
1:16:25
Speaker 1: efficiently because it wasn't We had to store what little
1:16:28
Speaker 1: we could get from the environment.
1:16:29
Speaker 2: Now we've got 300 million Americans in this food environment
1:16:32
Speaker 2: where when they walk out their front door, they see
1:16:35
Speaker 2: it's a Dunkin' Donut. They can lie in bed and
1:16:37
Speaker 2: order a Dunkin' Donut during 10 minutes.
1:16:39
Speaker 1: You don't even have to un-ass the car. They can't
1:16:41
Speaker 1: get through the window. No energy expenditure, energy in.
1:16:46
Speaker 2: So giving them this information might be fairly futile because-
1:16:50
Speaker 2: The temptation?
1:16:51
Speaker 1: I'm not here to tell people, again, I'm not here
1:16:53
Speaker 1: to tell people what they should or should not do.
1:16:55
Speaker 1: I'm just here to explain, like, why do we have
1:16:57
Speaker 1: all this? It's not mystery. It's all biological evolution. You
1:17:00
Speaker 1: understand biological evolution. Almost everything that I'm talking about makes
1:17:04
Speaker 1: perfect sense. And unfortunately, that's not part of our scientific
1:17:09
Speaker 1: literacy anymore.
1:17:10
Speaker 2: So we need what, discipline?
1:17:12
Speaker 1: Discipline is important. Discipline is important. You know, every major religion,
1:17:18
Speaker 1: had a point of fasting to be, whether you're Islamic, Judaism,
1:17:26
Speaker 1: or whatever, Catholicism, Hinduism, whatever. They always had some sort
1:17:31
Speaker 1: of fasting. Why do you do fasting? Because you want
1:17:34
Speaker 1: to purify your body. You want to become closer to God.
1:17:36
Speaker 1: You want to feel in control. And if you do
1:17:37
Speaker 1: it with prayer, it's even better. So There was a
1:17:45
Speaker 1: reason for doing all that. And people realized the ancients
1:17:49
Speaker 1: knew this kind of thing. But we don't do that anymore.
1:17:53
Speaker 1: We don't go 40 days without food like Jesus did
1:17:56
Speaker 1: in the deserts. But a human being, you could absolutely
1:18:00
Speaker 1: do that. I know because I can look at your weight,
1:18:03
Speaker 1: I can look at your size, and I can pretty
1:18:04
Speaker 1: much tell you how long you can go with before
1:18:06
Speaker 1: you died. And how do I know that? Because George Cahill,
1:18:10
Speaker 1: a good friend, late George Cahill, ran the Joslin Diabetes
1:18:13
Speaker 1: Center And he evaluated people that would just order only
1:18:17
Speaker 1: fasting until death and some of those constant prison camps
1:18:25
Speaker 1: and things. So he was able to know how long
1:18:29
Speaker 1: you could go. Now, what about Angus Barberi went 377
1:18:34
Speaker 1: days without food. George Cahill would fast some of these
1:18:38
Speaker 1: obese people for 250, 300 days. What happens inside their body?
1:18:42
Speaker 1: They're burning fat. So what happens is you burn fat. Okay,
1:18:46
Speaker 1: liver stores a lot of, bones store the minerals You
1:18:50
Speaker 1: can get minerals from your bones. You can get a
1:18:52
Speaker 1: lot of fat storage. Vitamins are stored in fat, a
1:18:56
Speaker 1: lot of vitamin D.
1:18:57
Speaker 2: Outside of the weight loss, what's going on? We said
1:19:01
Speaker 2: religious people used to fast to get closer to God,
1:19:04
Speaker 2: which seems to me to point to some sort of
1:19:05
Speaker 2: cognitive change.
1:19:06
Speaker 1: Yes, and that's from burning ketones.
1:19:08
Speaker 2: Okay.
1:19:09
Speaker 1: When you burn ketones, I said in the brain, when
1:19:10
Speaker 1: your brain starts shifting to ketones, your energy, the bang
1:19:14
Speaker 1: for the buck for each calorie that comes in from
1:19:16
Speaker 1: a ketone body increases the efficiency of oxidative phosphorylation.
1:19:20
Speaker 2: So you're more focused?
1:19:22
Speaker 1: Massively. And, you know, this is why our ancestors were
1:19:26
Speaker 1: the way that if you are dependent on killing some
1:19:30
Speaker 1: animal for your survival and you are out on the hunt,
1:19:35
Speaker 1: you are focused. Because if you're not focused, you're going
1:19:39
Speaker 1: to starve to death. So every sense organ in our
1:19:42
Speaker 1: body is super jacked when you're in these ketonic states.
1:19:48
Speaker 1: And these guys walking around with headphones, you know, all this.
1:19:51
Speaker 1: I mean, this is like depriving ourselves of the natural
1:19:54
Speaker 1: ways of our ancestry. Don't forget, you and I are
1:19:58
Speaker 1: not just here over the last, you know, 100, 300,
1:20:00
Speaker 1: 400 years. We are the descendants of members that are
1:20:05
Speaker 1: same as us, you know, hundreds of thousands of years ago.
1:20:08
Speaker 1: They just didn't have the technology that we have today.
1:20:12
Speaker 1: But if you could bring a Paleolithic man from, say, 500,000
1:20:15
Speaker 1: years ago, and you gave him a bunch of donuts
1:20:17
Speaker 1: and told him, oh, he went to heaven. You mean
1:20:19
Speaker 1: to tell me I don't have to go out and
1:20:20
Speaker 1: kill the elk anymore? They're going to hand me the
1:20:22
Speaker 1: food right through the window. Of course he's going to
1:20:24
Speaker 1: do that. You go in the cave and you throw
1:20:27
Speaker 1: a bunch of jelly-filled donuts into a bunch of cavemen
1:20:29
Speaker 1: who've been chewing on the half-eaten rat or something. You
1:20:34
Speaker 1: think they're not going to eat those jelly donuts? They
1:20:36
Speaker 1: have some chimpanzees live with a family down in Florida.
1:20:40
Speaker 1: I know there's some YouTube thing. The chimps, they're eating
1:20:43
Speaker 1: the food with the family. And then they give jelly
1:20:45
Speaker 1: sandwiches to the chimps. They're banging on the table. You'd
1:20:48
Speaker 1: think they were going to go crazy. Chimpanzees loving the
1:20:50
Speaker 1: jelly sandwiches.
1:20:51
Speaker 2: Do you have kids?
1:20:52
Speaker 1: Yes.
1:20:54
Speaker 2: What advice would you give to your children if they're
1:20:56
Speaker 2: listening to this now? about how to prevent their chance
1:21:00
Speaker 2: of getting sick from cancer?
1:21:01
Speaker 1: Well, they probably say, well, dad, how come you don't
1:21:03
Speaker 1: do a lot of the things? First of all, I'm
1:21:05
Speaker 1: not telling, I told you, I don't tell anybody what
1:21:07
Speaker 1: to do or how they do it. I'm just telling
1:21:09
Speaker 1: you the science behind why things work. Yeah, my children,
1:21:15
Speaker 1: my two sons, they're all very, very successful. And they said,
1:21:21
Speaker 1: if we ever got cancer, we would be doing the
1:21:24
Speaker 1: metabolic therapy if we were to ever get cancer. And
1:21:27
Speaker 1: I said, just keep exercising and do what you can
1:21:30
Speaker 1: do the best you can in our environment. I mean,
1:21:33
Speaker 1: don't get me wrong. I'm eating a jelly donut. I'm
1:21:35
Speaker 1: drinking beer. I'm drinking whiskey.
1:21:38
Speaker 2: Why?
1:21:38
Speaker 1: Because I like it. But I'm not going to be
1:21:40
Speaker 1: doing it all the time. I'm not going to be saying,
1:21:44
Speaker 1: I'm going to eat pizza, sure. But I'm not going
1:21:46
Speaker 1: to be not doing it. I do intermittent fasting. I
1:21:50
Speaker 1: don't eat for 18, 20 hours at a time. I
1:21:53
Speaker 1: do a lot of exercise over at the university, the
1:21:56
Speaker 1: gym and the facilities that we have. Um, but I,
1:21:59
Speaker 1: but I understand. And then if I were to get cancer,
1:22:02
Speaker 1: I would have to, um, bite the bullet and do
1:22:05
Speaker 1: what I'm, would do what I know works as much
1:22:07
Speaker 1: as it wouldn't be pleasurable, but it would be certainly
1:22:09
Speaker 1: a better alternative than being irradiated and poisoned. I'm telling
1:22:12
Speaker 1: you that.
1:22:13
Speaker 2: If that has brought your conviction to the point that
1:22:15
Speaker 2: you're so convinced that the real issue is this sort
1:22:17
Speaker 2: of metabolic dysfunction, um, Why aren't you optimizing your life
1:22:23
Speaker 2: to be sort of metabolically perfect?
1:22:25
Speaker 1: Well, because I live in the same society you do.
1:22:27
Speaker 2: Yeah.
1:22:27
Speaker 1: Okay. And fortunately, yes, our technology has improved significantly. You know,
1:22:35
Speaker 1: I'm not a monk. I'm not going to be in
1:22:37
Speaker 1: some monastery, you know, chanting something. I am a member
1:22:42
Speaker 1: of the society just as you are. And I enjoy
1:22:44
Speaker 1: the things that we have to offer us to make
1:22:47
Speaker 1: our lives a little bit more pleasurable. There's nothing like
1:22:49
Speaker 1: sitting down over a nice meal and having a discussion
1:22:52
Speaker 1: with some wine and enjoying it. Enjoy the moment. But
1:22:56
Speaker 1: not to be locked into that kind of diet and
1:22:59
Speaker 1: lifestyle all the time puts you at risk.
1:23:03
Speaker 2: There's an election going on in the United States at
1:23:05
Speaker 2: the moment, Trump versus Kamala Harris. If you won the
1:23:09
Speaker 2: election and you became president of the United States and
1:23:12
Speaker 2: you had to introduce some regulations or some laws around
1:23:16
Speaker 2: food and all of these kinds of things, what would
1:23:18
Speaker 2: you do?
1:23:19
Speaker 1: Well, I think you're talking about a food industry. You're
1:23:23
Speaker 1: talking about a multidimensional economy. I would not, again, you
1:23:30
Speaker 1: don't want government to tell you what you should do.
1:23:34
Speaker 1: You should make the choices, but you have to recognize
1:23:37
Speaker 1: are there choices and what are these choices? Right now,
1:23:40
Speaker 1: we're not seeing or understanding how things harm people. If
1:23:47
Speaker 1: we have an obesity epidemic and that would put you
1:23:49
Speaker 1: at risk for all these horrific chronic diseases, why do
1:23:53
Speaker 1: they not know that?
1:23:54
Speaker 2: We introduced some regulation in the UK regarding smoking, so
1:23:57
Speaker 2: you can't smoke inside anymore.
1:23:59
Speaker 1: But you see, your secondhand smoke could impact negatively the
1:24:03
Speaker 1: person sitting next to you. This obese person's personal choice
1:24:08
Speaker 1: to be obese is not going to make you obese
1:24:11
Speaker 1: or sick. So this is a different kind of a situation.
1:24:15
Speaker 1: That has to come from internal to the person. And
1:24:17
Speaker 1: they have to be concerned with their own health.
1:24:19
Speaker 2: What about drugs though? Like cocaine is not legal. So
1:24:22
Speaker 2: why can't they intervene to say you can't have Dunkin' Donuts?
1:24:26
Speaker 2: Because they're both going to harm the individual.
1:24:30
Speaker 1: I think you'd get a revolution if you can't eat
1:24:32
Speaker 1: a Dunkin' Donut. You're not going to get a revolution
1:24:34
Speaker 1: if you can't have cocaine. You try to go down
1:24:38
Speaker 1: here in Brooklyn and take away all these donuts from people.
1:24:41
Speaker 1: You're going to see they're going to go. You know,
1:24:44
Speaker 1: it's like, it's personal choices. I mean, I like Dunkin' Donuts.
1:24:47
Speaker 1: I mean, I like the coffee especially. But you can
1:24:51
Speaker 1: go to a donut shop and get some of these
1:24:53
Speaker 1: crullers and jelly fills and honey dipped. Are you kidding me?
1:24:56
Speaker 1: These things are delicious. You ever get these blueberry muffins?
1:24:58
Speaker 1: You tremble when you eat some of this stuff. You know,
1:25:01
Speaker 1: and I'm not going to take that away from me.
1:25:02
Speaker 1: But if I want one, I'm not going to be, oh,
1:25:04
Speaker 1: every day I got to eat. No, I just don't
1:25:06
Speaker 1: eat it. On the weekend, I might get one. And
1:25:09
Speaker 1: even sometimes two or three weeks, months go by before
1:25:11
Speaker 1: I'll get one. But when you get it, man, you
1:25:15
Speaker 1: enjoy it. You really love it.
1:25:17
Speaker 2: Are you hopeful?
1:25:18
Speaker 1: I am very hopeful. Because when the science comes, you
1:25:22
Speaker 1: can't suppress the truth. It's going to come out. The evidence,
1:25:26
Speaker 1: the scientific evidence is there. I'm documenting this scientific. And
1:25:30
Speaker 1: it's based on the shoulders of Otto Warburg. Are you
1:25:32
Speaker 1: kidding me? I mean, this was a giant in the
1:25:34
Speaker 1: field of biochemistry. It's not like I made this stuff up.
1:25:37
Speaker 1: I'm just extending what he has done to a new dimension.
1:25:40
Speaker 1: and putting it into a practical application, which he had
1:25:43
Speaker 1: never done. So it's just an extension of the knowledge
1:25:47
Speaker 1: base over this time.
1:25:48
Speaker 2: Why do you care so much?
1:25:50
Speaker 1: Why do I care so much? You know, I'm not
1:25:53
Speaker 1: in it for the money. You know what I'm in
1:25:55
Speaker 1: it for? I want to see the scientific principles substantiated.
1:26:02
Speaker 1: If you know that you can keep these people alive
1:26:05
Speaker 1: at a higher quality of life based on the knowledge
1:26:07
Speaker 1: of the science that's doing that, that's gratification, man. It's
1:26:11
Speaker 1: gratification to know that these– because you were right on
1:26:16
Speaker 1: understanding the mechanism of the problem. And if you say–
1:26:20
Speaker 1: if we do it the way– we're writing a big
1:26:22
Speaker 1: treatment protocol as we speak. It's under review, a really
1:26:25
Speaker 1: comprehensive treatment protocol. And we institute that in the clinic.
1:26:28
Speaker 1: And for glioblastoma patients and these advanced cancers, they're not
1:26:32
Speaker 1: living a few extra months. They're living several years longer. Why?
1:26:36
Speaker 1: Because you knew the science. What's wrong with that? That's– gratification.
1:26:42
Speaker 1: You don't have to make a billion dollars on that.
1:26:44
Speaker 1: All you have to know is that all those folks
1:26:46
Speaker 1: are living longer because you understood the science that was
1:26:48
Speaker 1: put into practical application. Our research is supported by philanthropy
1:26:54
Speaker 1: and private foundations. That money allows me to do these experiments,
1:27:00
Speaker 1: to test what I'm testing on preclinical models, and then
1:27:03
Speaker 1: we translate it back into the clinic directly. And we see,
1:27:06
Speaker 1: like Pablo Kelly, he should have been done. He should
1:27:08
Speaker 1: have been done Years and years ago. He lived all
1:27:11
Speaker 1: those years extra. He's had a wife and he's got kids.
1:27:14
Speaker 1: He didn't have to have his sperm frozen. He didn't
1:27:16
Speaker 1: have to have any of that stuff done. What's wrong
1:27:18
Speaker 1: with that? I'm seeing people that should have been dead
1:27:21
Speaker 1: a long time ago and they're still alive. And they're saying,
1:27:24
Speaker 1: I'm doing fine. I get calls from people. Jeez, I
1:27:26
Speaker 1: thought that guy would have been a goner. He's still alive.
1:27:28
Speaker 1: He's doing well. I said, that keeps me going because
1:27:32
Speaker 1: it tells me that we're on the right path. This
1:27:35
Speaker 1: is a solvable problem. This cancer This cancer can be
1:27:39
Speaker 1: dropped significantly. You can take away the fear. People now
1:27:43
Speaker 1: put it on their shoulders. I know what to do,
1:27:45
Speaker 1: how to do it. I'm going to follow this. Will
1:27:47
Speaker 1: it work for everybody? No, but it will help a
1:27:49
Speaker 1: lot of people, much more than what we have today.
1:27:52
Speaker 1: But it's paradigm change, massive paradigm change. So they will
1:27:57
Speaker 1: come to know. It's just a matter of time. I
1:27:59
Speaker 1: don't know how long it's going to take, but I
1:28:00
Speaker 1: ain't going anywhere. I'm continuing to do this. I'm going
1:28:03
Speaker 1: to get better and better results, and we're going to
1:28:05
Speaker 1: keep pushing. I've published these case reports in the scientific literature.
1:28:08
Speaker 1: Let the scientific field make their decision on the results
1:28:12
Speaker 1: from these papers.
1:28:13
Speaker 2: And if you are to succeed, what happens?
1:28:16
Speaker 1: People improve. I'm not going to live forever. But I
1:28:21
Speaker 1: know that what I've done with following Otto Warburg and
1:28:24
Speaker 1: cleaning up the misconceptions and misunderstanding of why he was
1:28:28
Speaker 1: stalled when the field ran off chasing genes, we've got
1:28:31
Speaker 1: to bring the Bring it back on track. It's a
1:28:33
Speaker 1: metabolic problem with metabolic solutions. So that will help a
1:28:37
Speaker 1: lot of people. But it's also going to change it.
1:28:40
Speaker 1: of the way people are thinking about this. But I
1:28:43
Speaker 1: can tell you, they want to open clinics. I get
1:28:45
Speaker 1: calls from Asia, Africa, South America. They want to open clinics.
1:28:50
Speaker 1: People are being brutalized by a system that's not working.
1:28:53
Speaker 1: Don't forget, besides the terrible physical toxicity, people are going
1:28:59
Speaker 1: bankrupt Their marriages are falling apart because they can't pay
1:29:03
Speaker 1: for the expensive drugs on these cancer things. And they
1:29:05
Speaker 1: die and the bills are passed on to their loved ones.
1:29:08
Speaker 1: This is immoral stuff.
1:29:09
Speaker 2: Is there a particular case study that's broken your heart
1:29:12
Speaker 2: more than any others?
1:29:14
Speaker 1: Trudy DuPont, who originally let me, we built a glucose
1:29:19
Speaker 1: ketone index calculator on her. Pablo is still, we're still
1:29:23
Speaker 1: devastated by Pablo's loss because Pablo was a, A guy
1:29:27
Speaker 1: that I've known for 10 years worked him through and
1:29:30
Speaker 1: then all of a sudden he gets a cerebral hemorrhage
1:29:32
Speaker 1: and dies. He was our poster child for how long
1:29:34
Speaker 1: you could live with a glioblastoma on metabolic therapy. But
1:29:38
Speaker 1: he didn't die from the cancer. You have some others
1:29:41
Speaker 1: that we wish they could have lived a little bit
1:29:43
Speaker 1: longer with the appropriate help. What I find is that
1:29:47
Speaker 1: sometimes within the family, there's a lot of– the guy,
1:29:51
Speaker 1: he says, I really want to do what you're doing.
1:29:53
Speaker 1: But my wife and kids say I'm foolish to do that.
1:29:55
Speaker 1: So it's still a very– we're in a very early
1:29:59
Speaker 1: stage of this. We haven't really worked it out into
1:30:03
Speaker 1: an effective standard yet. It will come. So people– and
1:30:07
Speaker 1: the other members of the family get super help. When
1:30:08
Speaker 1: they all work together and they do it, everybody says
1:30:11
Speaker 1: I never felt so healthy in my life. Guy Tannenbaum
1:30:15
Speaker 1: had advanced prostate cancer. He wrote a book and he's
1:30:17
Speaker 1: on the web and he had hypertension, high blood pressure, overweight,
1:30:21
Speaker 1: more obesity, everything. And then he does several 18-day water-only fasts,
1:30:27
Speaker 1: got himself. Everything, all these things went away. His diabetes
1:30:31
Speaker 1: went away, his hypertension, high blood pressure, and the cancer
1:30:34
Speaker 1: can't be found. So is he cured? I have no idea.
1:30:37
Speaker 1: But he's managed? Yes, he's managed. And he's healthier. So
1:30:40
Speaker 1: what's wrong with that? Isn't that ultimately what medicine wants
1:30:44
Speaker 1: to do? Keep people alive longer and a healthier quality
1:30:48
Speaker 1: of life? How many more do we need? They say, oh,
1:30:51
Speaker 1: that's a fluke. That's a fluke. That's a fluke. That's
1:30:53
Speaker 1: a fluke. That's a fluke. How many damn flukes do
1:30:55
Speaker 1: you want?
1:30:55
Speaker 2: If there's someone listening now, and I'm sure there's going
1:30:57
Speaker 2: to be many thousands and tens of thousands of people
1:31:00
Speaker 2: listening that are currently battling cancer, have early stage diagnoses.
1:31:06
Speaker 1: I know. I feel bad about this because people say, oh,
1:31:09
Speaker 1: I want to do metabolic therapy. Where can I go?
1:31:11
Speaker 1: And they go to their local hospital and get slapped down.
1:31:13
Speaker 1: There's no evidence. Everything that should come out of my
1:31:16
Speaker 1: mouth has never been taught to me in medical school.
1:31:18
Speaker 2: So what do you say to those people?
1:31:21
Speaker 1: You know, I say I'm sorry that the medical establishment
1:31:27
Speaker 1: has not come to recognize what I'm saying. And then
1:31:30
Speaker 1: I tell them, right, you know, the change has to
1:31:34
Speaker 1: be coming from the people. It ain't going to come
1:31:35
Speaker 1: from the top medical schools. They are doing what they're doing.
1:31:39
Speaker 1: The status quo is very profitable. The status quo is
1:31:43
Speaker 1: very effective for these people, but it's not helping the
1:31:46
Speaker 1: cancer patient as well as it can. And don't forget,
1:31:49
Speaker 1: we're not throwing out all this stuff. We're just asking
1:31:51
Speaker 1: people to know how to use the tools we have
1:31:53
Speaker 1: in a better way. We don't have to throw out immunotherapies, radiation.
1:31:57
Speaker 1: We don't have to throw out toxic poisons. We just
1:32:00
Speaker 1: have to know better how to use it when the
1:32:02
Speaker 1: patient is in this new state. And the data will
1:32:04
Speaker 1: prove it. But who's going to do that? Who's going
1:32:08
Speaker 1: to do that? The doctor says, I'd love to do this,
1:32:10
Speaker 1: but I'm going to lose my license if I do it.
1:32:12
Speaker 1: What's going on with that? They wrote the standard of
1:32:15
Speaker 1: care as if it were ingratiated. It can't be changed.
1:32:17
Speaker 2: No.
1:32:18
Speaker 1: No. They should be flexible. When new evidence comes up,
1:32:20
Speaker 1: I don't believe your evidence. What number do you not believe?
1:32:23
Speaker 1: What piece of science do you not believe on this? Well,
1:32:26
Speaker 1: I haven't read it. You can't be right when 99%
1:32:29
Speaker 1: of the world says it's this way and you're saying
1:32:31
Speaker 1: it's something different. That's confirmation bias. You're not looking at
1:32:34
Speaker 1: the numbers. And then when they get cancer, you come to, hey,
1:32:36
Speaker 1: what can you do for me? It's like that. But yes,
1:32:41
Speaker 1: it has to change. It will change because we're on
1:32:43
Speaker 1: the momentum to move it. People are coming to know this.
1:32:47
Speaker 1: And once the change happens, it's going to be like
1:32:49
Speaker 1: a major, major change. And people are going to have
1:32:52
Speaker 1: to just readjust.
1:32:54
Speaker 2: Thomas, we have a closing tradition on this podcast where
1:32:56
Speaker 2: the last guest leaves a question for the next guest,
1:32:58
Speaker 2: not knowing who they're going to be leaving it for.
1:33:01
Speaker 2: And the question that's been left for you is, imagine
1:33:05
Speaker 2: the end of your life. Your closest friends and family
1:33:09
Speaker 2: are at your funeral. What do you imagine or hope
1:33:12
Speaker 2: they say about you?
1:33:17
Speaker 1: He changed the course of cancer treatment for the world. It,
1:33:27
Speaker 1: that's it. Dr.
1:33:29
Speaker 2: Thomas Seyfried, that is exactly what you're doing. And I
1:33:34
Speaker 2: think that's an extremely, you know, I can't even find
1:33:37
Speaker 2: a word that describes the profundity of such a mission
1:33:41
Speaker 2: because so many people are struggling with cancer as if
1:33:44
Speaker 2: it is this sort of opaque black box of A
1:33:47
Speaker 2: disease that strikes us at random and picks on people
1:33:50
Speaker 2: like roulette and debilitates their lives out of the blue.
1:33:53
Speaker 2: And having more information out there about the root causes
1:33:56
Speaker 2: of these issues turns the lights on and allows us
1:33:59
Speaker 2: to go in search of better solutions to what has
1:34:02
Speaker 2: always been a really, really complex, hard to understand disease.
1:34:06
Speaker 2: Your work runs almost entirely, I believe, on philanthropic donations, right?
1:34:11
Speaker 1: That's right.
1:34:12
Speaker 2: So that's people that.
1:34:13
Speaker 1: They make donations to both my university, Boston College, which
1:34:18
Speaker 1: is a Jesuit university in Chestnut Hill, Massachusetts. And we
1:34:22
Speaker 1: follow the Jesuit philosophy of service to others predominantly. And
1:34:27
Speaker 1: private foundations.
1:34:28
Speaker 2: So if someone wants to make a donation, where do
1:34:30
Speaker 2: they go? Do they go to your website? I know
1:34:31
Speaker 2: there's a donation button.
1:34:33
Speaker 1: They go primarily to our university. They can just... On
1:34:38
Speaker 1: my university biology webpage, there's a donation button. And Travis
1:34:42
Speaker 1: Christopherson's Foundation for Metabolic Cancer Therapies, which is a 503 foundation,
1:34:48
Speaker 1: he supports our research through philanthropic donations to his foundation.
1:34:53
Speaker 2: I would urge anyone that wants to support your mission
1:34:55
Speaker 2: to go to your university website. There's a donation button there,
1:34:59
Speaker 2: which I saw earlier on. Click that button and they
1:35:01
Speaker 2: can make a donation.
1:35:02
Speaker 1: That's right. And Travis Christopherson's foundation. which is the Foundation
1:35:09
Speaker 1: for Cancer Metabolic Therapies. It's a 503 foundation, Travis Christopherson's.
1:35:15
Speaker 1: When people email me, I send them the links to
1:35:18
Speaker 1: those foundations. I cannot accept personally any money from anybody.
1:35:22
Speaker 1: That's one thing. That's one thing. I'm not here. So
1:35:24
Speaker 1: people say, oh, I want to give you money to
1:35:26
Speaker 1: do it.
1:35:26
Speaker 2: No, no, no.
1:35:26
Speaker 1: I can't. You have to give it to the university
1:35:28
Speaker 1: that comes through me through the appropriate channels to support
1:35:31
Speaker 1: my research through the university. Dr.
1:35:33
Speaker 2: Thomas Seyfried, thank you so much for your time today.
1:35:35
Speaker 2: And I'm hugely inspired and enlightened by everything we've discussed.
1:35:40
Speaker 2: And I think there's a bunch of very straightforward practical
1:35:43
Speaker 2: things I'll be implementing in my life, specifically buying one
1:35:46
Speaker 2: of those bloody machines so that I can keep on
1:35:48
Speaker 2: my GKI index.
1:35:49
Speaker 1: Yeah, GKI.
1:35:51
Speaker 2: GKI index.
1:35:52
Speaker 1: Yeah, glucose ketone index. Well, listen, thank you very much
1:35:54
Speaker 1: for having me here because your programs and others alert
1:35:59
Speaker 1: people to know that there are alternatives. effective alternatives. And
1:36:03
Speaker 1: once the system changes, the outcomes will not be so
1:36:07
Speaker 1: bleak as we currently have them today.
1:36:15
Speaker 2: Isn't this cool? Every single conversation I have here on
1:36:19
Speaker 2: the Diary of a CEO, at the very end of it,
1:36:20
Speaker 2: you'll know, I asked the guest to leave a question
1:36:24
Speaker 2: in the Diary of a CEO. And what we've done
1:36:27
Speaker 2: is we turned every single question written in the Diary
1:36:30
Speaker 2: of a CEO into into these conversation cards that you
1:36:34
Speaker 2: can play at home. So you've got every guest we've
1:36:37
Speaker 2: ever had, their question, and on the back of it,
1:36:40
Speaker 2: if you scan that QR code, you get to watch
1:36:44
Speaker 2: the person who answered that question. We're finally revealing all
1:36:49
Speaker 2: of the questions and the people that answered the question.
1:36:53
Speaker 2: The brand new version two updated conversation cards are out
1:36:57
Speaker 2: right now at theconversationcards.com. They've sold out twice instantaneously. So
1:37:02
Speaker 2: if you are interested in getting hold of some limited
1:37:05
Speaker 2: edition conversation cards, I really, really recommend acting quickly.
1:37:08
Speaker 1: So Thank you.