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Diabetes Core Update Nov 2025

This issue will review:

1. Effects of Semaglutide With or Without Concomitant Mineralocorticoid Receptor Antagonist Use in Participants With Type 2 Diabetes and Chronic Kidney Disease: A FLOW Trial Prespecified Secondary Analysis - Diabetes Care

2. Orforglipron, an Oral Small-Molecule GLP-1Receptor Agonist, in Early Type 2 Diabetes – NEJM

3. Orforglipron, an Oral Small-Molecule GLP-1 Receptor Agonist for Obesity Treatment – NEJM

4. Dementia Risk in People With Type 1 Diabetes and Associated Risk Factors – Diabetes Care

5. Impact of baseline GLP-1 Receptor Agonist Use on Albuminuria Reduction…

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