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The Hidden Male Factor Contributing to Infertility
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Sperm DNA fragmentation occurs when the genetic material inside sperm is damaged or broken. Even when a standard semen analysis shows normal sperm count, movement, and shape, high DNA fragmentation can reduce the sperm’s ability to fertilize an egg properly, impair embryo development, lower implantation potential, and increase the risk of early pregnancy loss. For this reason, sperm DNA fragmentation can be an important hidden contributor to unexplained infertility, particularly when routine male fertility testing appears normal.
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