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Navigating First-Line CLL Treatment with Drs. Kerry Rogers, William Wierda & Catherine Coombs

With more targeted therapies available for CLL, how are clinicians navigating the growing number of first-line treatment options?

Drs. Kerry Rogers, William Wierda, and Catherine Coombs discuss the evolving CLL treatment landscape, including fixed-duration versus continuous therapy, BTK- and BCL-2 inhibitor–based approaches, and how disease biology, comorbidities, treatment logistics, and patient preferences can guide treatment selection.

Topics discussed:

Fixed-duration vs. continuous first-line therapy

Choosing among BTK inhibitor-based strategies

Acalabrutinib + venetoclax and venetoclax +…

The skinny

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