Latest / Decera Clinical Education Oncology Podcast
Evolving Role of B7-H3–Directed ADCs in the Extensive-Stage Small-Cell Lung Cancer Treatment Landscape
In this podcast episode, Charles Rudin, MD, PhD, and Mark A. Socinski, MD, discuss current gaps and clinical needs for patients with relapsed ES-SCLC, and the evolving role of B7-H3–directed antibody–drug conjugates in the management of patients with ES-SCLC, including:
Clinical needs for relapsed ES-SCLC
Scientific rationale for targeting B7-H3 and other tumor-associated antigens in SCLC
ADCs, T-cell engagers, chemotherapy-based approaches, maintenance strategies, and ongoing clinical trials for ES-SCLC
Recent efficacy and safety data for B7-H3–directed ADCs in ES-SCLC, including I-DXd…
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