440-Harnessing the Microbiome for Cancer Therapy

Paper Talk · Jan 28, 2026 · 16m

This review explores the intricate relationship between the human microbiome and cancer development, highlighting how microbial communities influence disease progression and treatment outcomes. Research indicates that specific bacteria and their metabolites can trigger genotoxicity, drive chronic inflammation, and alter the immune landscape within the tumor microenvironment. These microbial processes significantly impact the efficacy and toxicity of conventional treatments like chemotherapy and immunotherapy by modulating drug metabolism and T cell activity. Consequently, scientists are…