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The Molecule That Should Have Been Medicine: How DOET Died
The Molecule That Should Have Been Medicine: How DOET Died
Five times the safety margin between a therapeutic dose and a hallucinogenic one made DOET anomalous among mid-century psychedelics, yet that five-fold gap did not save it from being classified Schedule I. How did a patented molecule with documented human trials and a clear therapeutic window die because of a handful of street-distributed pills in San Francisco?
In this episode, we trace the chain of events from Alexander Shulgin’s lab work at Dow Chemical to formal human trials at Johns Hopkins, and the summer of 1967 in…
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