1290-Developmental Cell & Atlas of Embryonic Chronology
Researchers have developed the mouse developmental Cell and Lineage Atlas (mdCLA), a massive single-cell transcriptomic resource encompassing 37 time points from the 2-cell stage to birth. This comprehensive dataset covers two million cells and utilizes deep sequencing to identify specific cell types and genetic markers that were previously undetectable. By comparing this atlas to existing studies, the authors demonstrated its superior ability to profile gene expression and lineage relationships across the entire embryonic period. The study specifically identifies a shift in nephron…
The skinny
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