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When a Street Panic Silenced a Potential Psychedelic Medicine

When a Street Panic Silenced a Potential Psychedelic Medicine

A single corporate decision erased a patent for a compound that promised antidepressant effects without hallucinations. DOET, nicknamed Hecate, showed a therapeutic window estimated at five-fold or greater and produced no open-eye hallucinations in controlled tests - so why was it abandoned before it could become medicine?

In this episode, we trace the timeline from a 1966 patent filing through company withdrawal and a 1968 Johns Hopkins trial, asking how external social panic over a related street drug redirected scientific…

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