151-Scriabin: analysis of cell–cell communication
This paper introduces Scriabin, a novel computational framework designed for the comparative analysis of cell-cell communication (CCC) at single-cell resolution using single-cell RNA sequencing (scRNA-seq) data. The authors explain that traditional methods often aggregate cell data, which can obscure important biological details, and detail how Scriabin overcomes this by analyzing interactions at the individual cell level without aggregation or downsampling. The framework offers three main workflows—the cell-cell interaction matrix (CCIM), summarized interaction graph, and interaction program…
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