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Melatonin and Your Heart: New Warning and What Science Knows

In this episode, I’m unpacking a new warning that caught a lot of people off guard: a late-2025 conference abstract suggesting long-term melatonin use may be linked to higher rates of heart failure and worse outcomes. The headline is scary, but I’m going to walk you through what it actually means, what it doesn’t prove, and why this one study raises questions that a single abstract can’t answer.

I’ll explain why melatonin isn’t just a “natural sleep gummy.” It’s a hormone and a timing signal, a darkness message that helps run your circadian clock. And because your circadian system also helps…

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