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Your Mitochondria Have Their Own Clock — and It May Control How Fast You Age

In this Deep Dive, Dr. Mike Belkowski explores a fascinating question at the intersection of circadian biology and mitochondrial science: What if mitochondria do not merely respond to the body’s clock, but actively help keep it?

Drawing from two reviews on mitochondrial chronobiology, the episode examines how mitochondrial fusion, fission, energy production, mitophagy, NAD metabolism, and oxidative stress follow rhythmic patterns throughout the day. It also breaks down the two-way conversation between the nuclear clock and the mitochondria, including how metabolic signals such as NAD, ATP…

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