Janus kinase inhibitor response falls with BMI, not placebo

AudioScholar Rheumatology Weekly · Aug 6, 2026 · 10m

Editor's Pick: Impact of BMI on response to Janus kinase inhibitors in rheumatoid arthritis: an individual patient data meta-analysis of randomised controlled trials (The Lancet Rheumatology, 2026)

Welcome to This Week in Rheumatology. This week we're covering 8 notable papers spanning treatment optimisation in rheumatoid arthritis, connective tissue disease lung involvement and guideline navigation, and two very different attempts to move the needle on osteoarthritis pain. Let's dive in.

This week's papers:

Navigating evidence-based recommendations for the management of systemic sclerosis —…