1046-Visualizing the First Steps of Tumorigenesis
The paper reviews recent technological breakthroughs that allow scientists to observe the very first stages of cancer development within living organisms. By utilizing intravital microscopy, tissue clearing, and spatial transcriptomics, researchers can now visualize how mutated cells either expand into tumors or are eliminated by their surroundings. These tools reveal that tumor initiation is not just a result of genetic mutations, but is heavily influenced by complex interactions between mutant clones and the healthy tissue environment. The authors highlight how cellular competition and…
The skinny
The skinny isn't ready yet — notes appear once the transcript is processed.