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Systemic Lupus Erythematosus (SLE)

Welcome to the Evidence at the Bedside ABIM Edition! In this episode, we take a comprehensive deep dive into Systemic Lupus Erythematosus (SLE), a multisystem autoimmune disease. We explore the epidemiology of the condition, including why approximately 90% of adult patients are female. Join us as we break down the complex clinical manifestations, ranging from the classic acute cutaneous malar rash to severe kidney, cardiovascular, and neuropsychiatric involvement. We also review the 2019 EULAR/ACR classification criteria, high-yield diagnostic markers like anti-double-stranded DNA and…

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