
1353-Chronic Stress and Glioblastoma
The research explores the complex biological relationship between chronic stress and the progression of cancer, specifically focusing on glioblastoma. Scientific diagrams illustrate how the HPA axis and the sympathetic nervous system trigger a systemic response that involves ADRB2+ monocytes and C5aR1+ macrophages. This internal physiological shift results in a suppressed immune environment, characterized by a decrease in NK cells, which ultimately facilitates tumor growth. The sources also highlight potential therapeutic interventions, such as the drug avacopan, to disrupt these…
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