Pharma 27: Ischaemic Heart Disease - Matching Supply to Demand
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This episode frames ischaemic heart disease as a problem of mismatch: myocardial oxygen demand exceeding supply. Rather than focusing on individual drugs, we build a physiological map of coronary flow, preload, afterload, heart rate, and contractility—and then show how anti-anginal therapies act by reshaping these variables. When understood this way, ni…
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