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What is new in intracoronary physiology in 2026 and why does it matter?

Javier Escaned and Niels Van Royen explore the evolving role of physiology in coronary assessment, with a focus on angiography-derived and imaging-derived indices, highlighting the growing potential of AI-driven tools to integrate anatomical and functional data, enabling more comprehensive and flexible decision-making without the need for pressure wires.

While these technologies offer significant advantages, including real-time guidance and improved lesion localisation, challenges remain regarding heterogeneity between systems and the need for robust clinical validation. The conversation also…

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