Micro 64: Systemic Mycoses Caused by Dimorphic Fungi
This episode explores systemic infections caused by dimorphic fungi, organisms that exist as moulds in the environment and transform into yeast forms within host tissue. Drawing from Murray’s Chapter 64, it examines how inhalation initiates pulmonary infection with potential dissemination.
The major pathogens include:
* Histoplasma capsulatum
* Blastomyces dermatitidis
* Coccidioides species
* Paracoccidioides brasiliensis
These fungi produce airborne spores in soil or environmental reservoirs. Inhaled spores reach the alveoli, where temperature-triggered transformation into yeast (or…
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