Can Brain Tissue Be Regenerated? Inside the ReGenBrain Trial | Dr. Roberta Diaz Brinton

Let's Talk Alzheimer's · Sep 17, 2026 · 14m

Can brain tissue be regenerated? We spoke with Roberta Diaz Brinton, PhD, director of the Center for Innovation in Brain Science at the University of Arizona, about the ReGenBRAIN clinical trial. This Phase 2 study is testing whether the drug allopregnanolone (“Allo”) can help repair brain damage and improve thinking in people with mild Alzheimer’s who carry the APOE ε4 genetic risk factor. Dr. Brinton explains how the trial works, who can enroll, and why this approach holds promise. For a deeper dive into vascular dementia, watch our full conversation with Dr. Brinton, part of the Zoom In on…