Nero and the Plague of 65 AD: The Epidemic That Shook Rome

Nero: Mad Tyrant or Misunderstood Emperor? — Fexingo History · Jul 10, 2026 · 5m · transcript

In 65 AD, as Nero faced the aftermath of the Pisonian Conspiracy and his mother's murder, a devastating plague swept through Rome and Italy. This episode explores the epidemic's origins, spread, and mortality, drawing on Tacitus, Suetonius, and Cassius Dio. We examine how the plague deepened Nero's paranoia, fueled popular unrest, and strained Rome's grain supply and economy. We also consider the plague's role in Nero's building projects, his reliance on the praetorian prefect Tigellinus, and the social panic that set the stage for the Great Fire's…