Non-Small Cell Lung Cancer | Oncology Today with Dr Neil Love: Management of RET Fusion-Positive Non-Small Cell Lung Cancer (Companion Video Lecture)

Research To Practice | Oncology Videos · Oct 25, 2022 · 24m

Featuring a slide presentation and related discussion from Dr Justin Gainor, including the following topics:

Biology of RET Genetic Alterations in Cancer (0:00)

Early Efforts to Target RET Alterations in Non-Small Cell Lung Cancer (NSCLC) (1:44)

Mechanisms of Action of Selective RET Inhibitors (3:58)

Clinical Trial Evidence Supporting Selpercatinib Therapy for RET-Altered NSCLC (5:04)

Updated Efficacy and Safety Results with Pralsetinib Therapy for RET-Altered NSCLC (13:14)

Mechanisms of Resistance to Selective RET Inhibitors (19:33)

CME information and select publications