947-Competitive Interactions Shape Mammalian Brain Network

Paper Talk · May 11, 2026 · 23m

This research from Nature Neuroscience utilizes computational whole-brain modeling to demonstrate that competitive interactions are essential for understanding how mammalian brain networks function. By analyzing data from humans, macaques, and mice, the authors found that models incorporating both cooperative and competitive ties more accurately replicate real-world brain activity than traditional models. These negative-valued interactions typically link regions with opposing biological traits, such as different gene expressions or cellular structures, and are characterized by long-range…