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Alzheimer's Research Shifts Focus Away From Protein Targets

For decades, Alzheimer's research has chased the same two protein targets with mounting disappointment—but a new inflection point is redirecting scientists to something happening much earlier in the disease, suggesting we may have been treating symptoms while missing the root cause entirely. This shift could reshape how we think about neurodegeneration and aging more broadly, and it hinges on understanding what actually goes wrong first—before the proteins accumulate.

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