Latest / Come Together with Ephraim Herschmann / Science Series 3: Dr Lisa Gabel / Neurology / Dyslexia / Mind Controlled Drones / Music & the Brain
Transcript
- 0:01Welcome to another episode of Come Together.
- 0:15And we're live. Doctor Lisa Gabel, how are you?
- 0:17Welcome. So thank you so much.
- 0:18Oh my gosh, I ruined it already. Thank you so much for coming up.
- 0:21How are you? I'm good.
- 0:23Thank you for inviting me. Thank you so much for getting
- 0:27back to me so quickly and just hopping on and I'm really,
- 0:31really excited, excited to talk to you because you study two
- 0:34things that I think are absolutely some of the most
- 0:38fascinating aspects of people, which is psychology and
- 0:42neurology. And I actually didn't know
- 0:47really the difference between them for a little bit.
- 0:50I know that I'm sure neurology sounding has a little bit more
- 0:53of a scientific basis. I know that psychology tends to
- 0:57be a little bit more observation.
- 1:01I mean it's people described it as soft science, right?
- 1:03Or softer science? They do, although I think some
- 1:06of the colleagues in psychology would argue against.
- 1:11That. So, so think of psychology as
- 1:14like behavior, cognition and experience, right What is
- 1:19happening? And think of neuroscience or
- 1:22neurology as how something is happening.
- 1:27So brain structure, function, biology.
- 1:30Neuroscience is actually a culmination of the majority of
- 1:34the natural sciences. It requires an understanding of
- 1:36physics and chemistry and biology and psychology in order
- 1:40to try and understand the connection between behavior and
- 1:46neural function. Right, right.
- 1:48So you kind of as I imagine you get a little, you definitely get
- 1:50a little bit of everything when you study neurology, you get a
- 1:53little bit of the, you get a little bit of everything like
- 1:55you just said. And then you'd want to just have
- 1:59a little more of an intensive or more concentrated perspective on
- 2:02the psychology side, I guess, from your end.
- 2:05So from my end. So my PhD is actually in
- 2:08Physiology and neurobiology, and I have a master's in psychology
- 2:15and behavioral neuroscience. So I've really, you know, gone
- 2:18from one end to the other. So my interest actually is, is
- 2:24quite broad. And I tend to study a lot of
- 2:27different things in a lot of different ways because I tend to
- 2:30just follow whatever the question is and then learn what
- 2:34I need to learn in order to answer that question.
- 2:38So I think it's all important. I that sounds super cool.
- 2:41I love that, especially because I think that when you're
- 2:43starting with a question as opposed to starting with an
- 2:45answer, then it gives you a lot more space to be creative and to
- 2:48kind of play around with a lot more, with a lot more in the
- 2:52playground. You know, as opposed to just
- 2:54having to box yourself into trying to find one particular
- 2:56solution that you hope to get. Exactly.
- 2:59And there's, you know, there are good reasons to, you know, be an
- 3:02expert in one thing and focus on that because we need that.
- 3:07But a lot of science now is very collaborative and very
- 3:11interdisciplinary or multidisciplinary in order to
- 3:14answer like complex questions. So I like sort of jumping down
- 3:18different rabbit holes and seeing where it takes me.
- 3:21Yeah. So, so how'd you get?
- 3:22So what was the first one of the first issues that you're trying
- 3:24to kind of get answers to or trying to understand?
- 3:28So actually the the students in my lab, I have like 5 different
- 3:32research projects going on at any one time.
- 3:34Some of them are related, some of them are not related.
- 3:36So I study brain computer interface with another professor
- 3:40in electrical and computer engineering.
- 3:42His name is Yi Chung Yu. He's phenomenal.
- 3:45We built that research program from the ground up.
- 3:48Neither one of us had done it before, but we saw a need and is
- 3:52a great way to bring our students from engineering and
- 3:55neuroscience together toward a common goal.
- 3:58But then I also study neurodevelopmental disorders
- 4:01like seizure disorder or dyslexia or autism.
- 4:07Dyslexia research is a really big component of my lab right
- 4:10now. We do both animal and human
- 4:12studies. How does dyslexia manifest in an
- 4:15animal? Answers that question a lot, and
- 4:20it's a great question because mice don't read, you know?
- 4:22So how, how how? Dyslexia and it is, you know,
- 4:26sort of a human feature. But so if you take reading and
- 4:32you break it down into it's very complex.
- 4:35Reading is very complex. It requires phonological
- 4:37processing, visual processing, auditory processing, working
- 4:40memory, so on and so forth. Well, I can study each one of
- 4:42those things in an animal. And there are different models
- 4:47of dyslexia based on, from a neural perspective, either
- 4:51malformations in the brain that are identified in humans,
- 4:54animals that have those spontaneously developing, or
- 4:58more commonly genetics. So there are certain genes
- 5:01associated with dyslexia. We can modify those genes in an
- 5:04animal. And then if you say you modify a
- 5:08gene and check the behaviors between an animal that has the
- 5:11gene modified and that an animal that doesn't, the behavior that
- 5:15is altered in the animal that has the gene modified, then you
- 5:19start to look at the connection between that gene and that
- 5:22behavior or that process. And then we can translate what
- 5:25we see in the animal to humans. So I also work with kids.
- 5:30Wow. Yeah.
- 5:32How how comfortable or how often or how many studies you have to
- 5:36do in an animal before you feel like you're ready to take, you
- 5:38know, to observe a kid or do take it to the next level.
- 5:42That isn't, that's an excellent question, and it probably
- 5:46depends on whatever your line of research is and and what you're
- 5:49doing. I've been studying dyslexia in
- 5:51some form with an animal model since I was a graduate student.
- 5:55So I've been at Lafayette College now for 20 years.
- 5:59So I've been doing this for quite some time.
- 6:01I won't tell you exactly how old.
- 6:05Yeah. So in my case there, I used a
- 6:10particular model of the disorder.
- 6:13It was a particular disruption in a gene called DCDC 2 in an
- 6:16animal. And one of the tasks that I did,
- 6:19I described it to people as, you know, on the back of the cereal
- 6:22boxes where they have the maze and you have to get the mouse to
- 6:25the cheek. It's very much like that.
- 6:29So we saw this really interesting finding, whereas if
- 6:33you altered the gene, that particular gene, the animal
- 6:37couldn't learn the task. Wow, remember it?
- 6:41Or would it be able to actually carry out the function?
- 6:44It could carry out the function, but it wouldn't is behavior
- 6:47would sort of stay stable over time.
- 6:48So if I put you in a maze, you would probably take a
- 6:52considerable amount of time and you would probably make some
- 6:55errors because you've never been in it before, right?
- 6:57But then the second time you were in the maze, you're like,
- 6:59OK, I've been here before and you'll be a little bit faster
- 7:02and you'll make fewer errors, and you get this nice little
- 7:04learning curve. So the mice that had this
- 7:07genetic mutation, it was flat. They never really learned the
- 7:10task. So people would always ask me
- 7:13the question that you just asked me.
- 7:15When I'd go to give talks, they'd be like, well, how can
- 7:18you really say that? You know, this is like human?
- 7:21And it's a fair enough question. So I read a paper by a
- 7:26scientist's name. I forgetting his first name.
- 7:29His last name is Shore. So Professor Shore had created a
- 7:32virtual version of this particular task, and he compared
- 7:35mice to humans, both males and females.
- 7:38And I'm like, oh, that's really interesting.
- 7:40So we created a virtual version and we compared our college
- 7:46kids, 18 to 22 year olds with mice and they had similar
- 7:50behaviors. And I'm like, oh, OK.
- 7:52So then I went a little younger and I did 8 to 12.
- 7:55And then Long story short, after years of going back and forth, I
- 7:59started testing kids with and without reading impairment to
- 8:03see whether or not kids with reading impairment were impaired
- 8:06at this task. And they are, which was
- 8:09interesting, especially since, you know, in mice we control
- 8:12everything about their environment, where they live,
- 8:15their genetics, everything. Humans are not, you know that
- 8:19restricted, right? They have a lot of experiences
- 8:22different, there are different genes associated with dyslexia.
- 8:24So it could be a whole mix. So I didn't actually expect to
- 8:27see anything. And the fact that I did.
- 8:31Hey everyone real quick if you're enjoying the show, click
- 8:34subscribe and rate the show. 5 stars helps a ton.
- 8:37Thanks so much. And I consistently do.
- 8:40I even went to Germany and I tested native German speaking
- 8:43children and children who are multilingual at an International
- 8:46School and I always do the same thing.
- 8:48If you have an impairment with reading or impaired at this
- 8:51particular task, now we're actually using it to identify
- 8:55kids with dyslexia before they can read.
- 8:57That's really cool. And I would imagine so are we
- 9:04misdiagnosing dyslexia as being a reading disorder and it's
- 9:07really ability to retain this kind of or at least from that
- 9:11gene, right, that like that mouse gene that you described
- 9:13earlier where it wouldn't be able to process the learning and
- 9:16have that learning curve, is that not?
- 9:18Not necessarily reading. So as a like I was saying
- 9:21before, reading is very complex, right?
- 9:23So there's lots of processes that underlie it.
- 9:25So you can have a child with reading impairment and they have
- 9:31this set of challenges and you could have another child's
- 9:35completely different set of challenges.
- 9:38So it's not it, it's not that it's not a reading disorder,
- 9:42it's that we were able to create a task or use a task that could
- 9:48tap into the same neural circuitry that is used for
- 9:52reading. And then see whether see how
- 9:55that's operating. Exactly.
- 9:57I see so cool. Then what do you do if it's not?
- 10:00And what are some, what are some potential treatments or some
- 10:03kind of breakthroughs that could respond or, or if there aren't,
- 10:08then how do you recommend someone with dyslexia learn, you
- 10:11know? That's, that's a great question
- 10:13because so with my, with the task that we do, we can identify
- 10:19kids who have a reading pair, but I still can't tell you what
- 10:22the specific impairment is, just that they haven't.
- 10:25So it's a nice way of identifying kids early so that
- 10:28they can go and get the additional testing, particularly
- 10:32if you are a non-native speaker. So a lot of our trouble is when
- 10:37you have somebody who is an English language learner, are
- 10:39they impaired at the task because of the language barrier
- 10:43or are they paired at the task because there's a reading
- 10:45deficit? So if you can take that factor
- 10:49out of the equation, it can be helpful.
- 10:51But there are lots of interventions that have been
- 10:54developed that are quite successful.
- 10:56The the challenge seems to be getting the child help as soon
- 11:01as possible because the earlier that the interventions are
- 11:04applied, the greater the success rate.
- 11:06Sure, I imagine that'd be the case.
- 11:08That makes a lot of sense. I'm curious.
- 11:10And I mean, I don't expect to know the answer.
- 11:13I'm just, I'm just thinking off the cuff.
- 11:15But you know, I, I'm, I'm Orthodox Jewish and so I am, I'm
- 11:19fluent in reading English, obviously, and Hebrew.
- 11:22And the difference between English and Hebrew from a
- 11:26reading perspective is enormous, right.
- 11:28And I think there's a couple other languages that go English
- 11:30is, I think left to right and then Hebrews right to left and
- 11:35enormously context driven. And so a lot of times I don't
- 11:42want no definitions of words until I I'm able to identify the
- 11:46root or the context in which, you know, it's, you know, it's
- 11:49just placed and the words around it.
- 11:52And then and then I get it and, and I may never even see the
- 11:56word again after that, you know, like it might even be like a one
- 11:58time use or something weird like that, as opposed to the English
- 12:00language, which I think requires a different part of our brain.
- 12:03Have you noticed any difference in terms of like you know,
- 12:06different languages that dyslexia manifests?
- 12:10Yeah, so, you know, it's really interesting and the the so in
- 12:16the United States we have a very non term transparent language.
- 12:19English is very non transparent, right.
- 12:22So there are exceptions to rules.
- 12:24And this letter has this sound in this condition, but not in
- 12:27that condition. But there are other languages
- 12:29which are are completely transparent.
- 12:32So Finnish is apparently not that I know or speak Finnish.
- 12:36It's a very transparent language.
- 12:38So the letter always has the sound regardless of the context.
- 12:41Hopefully I am picking the right language to describe that
- 12:45theory, but there. So there's a continuum and then
- 12:47there's also Lobo graphic languages which require images
- 12:51as opposed to let alphabetic languages which are letters and
- 12:54sounds. So that is actually one of the
- 12:58things that I was really curious about because depending on the
- 13:00type of language too also correlates with the incidence of
- 13:04reading impairment. So and so try so when I'm
- 13:12studying this, one of the things that I've really wanted to do is
- 13:15see how that type of language. So whether you're Lobo graphic
- 13:20or whether you're very transparent or non transparent
- 13:23language has any influence on the outcome of our study as and
- 13:27what influence that has on on reading, which is why I went to
- 13:31well, not the reason I went to Germany, but why I did the study
- 13:33in Germany, because their language is more transparent
- 13:37than English. And then I wanted to look at
- 13:39children who come from different language backgrounds.
- 13:41So, you know, multilingual children who might speak their
- 13:45primary language might be transparent and their and the
- 13:49another language that they speak might be non transparent and how
- 13:53that impacts Long story short, the the the task, the
- 13:59performance associated with reading still holds regardless
- 14:02of the, you know, the level of transparency of the language,
- 14:05which is interesting. But I'm, I'm really curious
- 14:08whether or not logo graphic languages which are more visual
- 14:12spatially needed would if the outcomes would be different
- 14:17because the task IU news absolutely requires visual
- 14:20spatial processing, right? So I'm wondering if the degree
- 14:24of that and the degree in which the language requires visual
- 14:27spatial processing, if they would correlate highly in terms
- 14:31of performance. So I don't have that answer yet.
- 14:34That's cool. Well, when you do, we'll get
- 14:36back on another podcast, talk about it because yeah, I love
- 14:40this stuff. And, you know, and I'm always
- 14:43thinking about this. I grew up, you know, I might,
- 14:45my, my grandfather taught my mom Hebrew.
- 14:48My mom spoke to us, but a little bit less profusely.
- 14:51And we're, you know, we're a little bit less fluent and
- 14:53naturally really, as things kind of go.
- 14:55And then my kids, you know, in particular, like I'm really not
- 14:59speaking a lot of Hebrew to them at all.
- 15:00And, you know, and my wife and I went on our honeymoon to Italy
- 15:08or Greece. We went to both.
- 15:09But in Greece, they told that everyone speaks every, you know,
- 15:12several languages when you, when you travel.
- 15:14And so we're, you know, we're hanging out talking a couple of,
- 15:17of local business owners just at a regular cafe or whatever, and
- 15:21they tell us a joke. What do you speak?
- 15:23Someone speaks three language, trilingual, Someone speaks 2
- 15:26languages, bilingual. And someone that speaks one
- 15:27language is American, you know, and there has to be something
- 15:33to, to speaking more than one language.
- 15:36My brother-in-law is from Brazil.
- 15:38He speaks Spanish, Portuguese, English, Hebrew.
- 15:41The way he thinks you could see is so different than I am.
- 15:45And, and I'm sure that it's because your brain is working
- 15:49and expanding to, to, to encompass all sorts of different
- 15:53contexts that's required for those different skills, right?
- 15:57Yeah, it's really my husband's actually.
- 15:59He's a native German speaker, but he also speaks English and
- 16:03Italian and he knows Latin and, you know, so I've and I always
- 16:08feel incredibly unintelligent when I go and meet all of his
- 16:12friends from Europe because they all speak multiple languages.
- 16:14It just seems to be and nothing gets Americans.
- 16:17I love America, but we not to, you know, push that as much.
- 16:21Ours are. I have 3 kids and they all take
- 16:24a language in in school. But it's not something and not
- 16:28in the same way it appears as in other countries.
- 16:32But yeah, it's it's really interesting to see.
- 16:36That was one of the reasons why I was curious about kids who are
- 16:38multilingual. They're living in Germany, but
- 16:43they're attending the school that's taught in English, and I
- 16:47was wondering how they would perform on these particular
- 16:51tasks. And although the performance was
- 16:54the same, there's still probably a great deal of difference in
- 16:58how they're processing the information as opposed to
- 17:02somebody who is monolingual. But unfortunately that that's
- 17:06one area that I haven't studied in a great.
- 17:08Yeah. And I imagine that there's so
- 17:11it's got to be such a dense study because there's so many
- 17:16factors to consider and there's so many different.
- 17:18And again, I guess you almost need your, your neurology, you
- 17:22know, I guess the neurological aspect where you kind of able to
- 17:25understand everything from a different part, you know, piece
- 17:29of the playing field. And then, and then you have to
- 17:31collect the, the data and kind of figure out what everything
- 17:34has in common. And I mean, that's got to be an
- 17:37enormous, it's got to be an enormous amount of research.
- 17:39Yes, absolutely. And fascinating.
- 17:42Yeah, for sure. It's got to be fun, you know,
- 17:44but I, but I imagine, you know, I can't imagine it's going to be
- 17:46like a 9 or 100 person study and you're like, Oh well, we figured
- 17:49it out, you know, like, I mean. Anecdotally, when, you know, I
- 17:52took French when I was in high school and when, you know, I was
- 17:56living in Germany and trying to remember German words, for
- 17:58whatever reason, the, the word, you know, in French, French
- 18:02would come out before the word in and, you know, So I'm very
- 18:04interested in how, you know, the circuitry behind that.
- 18:08I just haven't had the opportunity.
- 18:10I do that too, by the way, my, my, my most of the most of my Co
- 18:13workers for my sales job are they speak Spanish and they're,
- 18:16they're Dominican and I'll end up speaking instead of broken
- 18:20Spanish. I'll throw in a couple of Hebrew
- 18:22words every now because I'm not even saying the right thing and
- 18:24they, they look as confused as I am.
- 18:26But I mean, I, I, I, I'm just pulling from the right.
- 18:28I guess I'm just pulling from the wrong place.
- 18:30What are some other, what are some other, I guess reading or
- 18:34developmental diseases that or or yeah, I mean, do you call
- 18:37them diseases? How do you refer to them?
- 18:39Disorders? So there's actually a lot of
- 18:43debate about whether it should be considered a disorder or not.
- 18:46It's just, you know, we all have strengths and.
- 18:48Weakness. Right.
- 18:50And you know, I believe at least because I'm a neuroscientist
- 18:54that it all comes down to wiring and function.
- 18:57But just because you have a challenge in one area does not
- 19:00mean that you have challenge in all areas.
- 19:02And I know that, you know, people.
- 19:05So I have three children and they all have dyslexia, you
- 19:09know, they've had, I know, which is really unusual.
- 19:11What are the odds? It's crazy.
- 19:13The odds are so ridiculously low, you know, and they as much
- 19:19as many kids went through the the same issues in school where
- 19:23they were. You know, you sort of doubt your
- 19:24intelligence when you have a learning disability, regardless
- 19:27of what that learning disability is.
- 19:30You know, hearing it from their friends or expectations, even
- 19:33sometimes of teachers, although they've had phenomenal teachers,
- 19:37you know, and it, it, it can make you so in that I don't like
- 19:41to think of it as a disorder as much as it is a challenge.
- 19:44They have certain difficulties with learning certain types of
- 19:47things, but they are really exceptional in other areas.
- 19:50Being able to put connect different concepts together with
- 19:55something they could always do really rapidly and something
- 19:57that's very hard to teach. So, but we all have different
- 20:00strengths and weaknesses in different areas.
- 20:03Yeah, it's a great way to put it.
- 20:04But I have, Yeah, it's a great way to put it.
- 20:05I have a student of mine that he I teach high school and 9th this
- 20:09year is 9th, 10th and 12th, which is really fun spectrum of
- 20:15teenagehood. And one of my students was
- 20:19having a really hard time in the classroom and I always had a
- 20:21hard time in the classroom too. I was not a great student by any
- 20:23means and I put a lot of pressure on myself and whenever
- 20:27I take tests, my mind would just go blank no matter how much time
- 20:30I spent studying. What do you what do you, what do
- 20:33you think about that immediately?
- 20:35What was that thought I? Can't diagnose so to go on, but
- 20:42you know, I see kids struggling because of the area that I, I
- 20:46work in and because I work with kids and I often talk with
- 20:49parents, you know, I, I have these conversations with, with
- 20:54parents all the time. And I have, you know, college
- 20:57kids who are struggling with different difficulties.
- 20:59And it can, you know, it can be a number of things.
- 21:02And I really encourage people to, you know, go and seek help
- 21:05and find out, you know, what are your challenges and what are
- 21:08your strengths and, you know, build upon those strengths as
- 21:12you're trying to use interventions to improve where
- 21:16you have challenges. And a lot of times, I think
- 21:20people feel shame. Parents feel shame if they feel
- 21:23that they're, you know, somehow their child is at a disadvantage
- 21:26or a child feels shame because they have a learning disability
- 21:30and, you know, they think that says something about their
- 21:32intelligence, which it doesn't. I used to argue with my mom and
- 21:38my mom would be like, you're smart, like Emma, I love you.
- 21:41I'm your oldest son. Of course you're going to say
- 21:43I'm smart. There's no smart, but I don't
- 21:47think I'm that smart. I'm studying for bio for five
- 21:49hours and taking notes and I'm getting X and I don't know what
- 21:51to tell you. Like maybe I'm not smart, you
- 21:53know, And I really, and I really, really until I, until I
- 21:56got to college, I thought I was dumb as a doorknob.
- 21:58And I was like, I guess I happen to be nice and I guess I happen
- 22:00to like reading. But like, if I can't do these
- 22:03tests, I'm obviously not a smart dude, you know?
- 22:06Yeah. But there's there we're become
- 22:08sort of very rigid in, in how we assess a person, not even just
- 22:13yes, definitely intelligence, but just how we assess content
- 22:17knowledge, right? And you know, I've even done it
- 22:21myself where, you know, you teach a certain amount of of the
- 22:25topic of the content and then you give them a written test and
- 22:29you have so much time to complete the test.
- 22:31And you know, that's a challenge there.
- 22:34I mean, sometimes we absolutely have to do that.
- 22:37But there are other ways to get at that knowledge that a person
- 22:42might have, you know, and test anxiety is a real thing, right?
- 22:47And if you're really anxious about taking that test, you
- 22:50might not be able to focus on what's in front of you.
- 22:52And in actuality, you're not really taking anything in.
- 22:55So then it's hard to let somebody know, you know, your
- 22:59level of knowledge on that particular topic.
- 23:04So yeah, it, it is a challenge. And that doesn't mean, you know,
- 23:08having anxiety and doesn't on a test doesn't mean that you're
- 23:11anxious. It could just be the situation.
- 23:13It doesn't mean you have a learning disability.
- 23:16I mean, it could be anything. So the only way to really know
- 23:19is to to go and seek support. And yeah.
- 23:22Definitely. The professionals help you sort
- 23:24it out. Yeah, so when I so, so to that
- 23:28point. Exactly.
- 23:29So this student that I had that was having a hard time, I could
- 23:32see that he was brilliant. I could see, you could see when
- 23:34you're talking to someone with their eyes and how quickly
- 23:36they're processing what you're saying, that they're thinking
- 23:38and responding. And he just could not deal with
- 23:40school. You could see he was not one of
- 23:42these kids that sits behind a desk from from, you know, 8:00
- 23:45AM to 5:00 to 6:00 PM, which is really what the hours are.
- 23:49And so he actually ended up leaving the school and I ran
- 23:52into him at a local synagogue and I said, you know, and I, and
- 23:56I said hi and I and I went, went up to after, after, after the
- 23:59services. And I said, I just want to tell
- 24:01you, I was like, not everyone is meant to in the classroom.
- 24:06And that does not make you stupid by any means.
- 24:08I was like, you are clearly brilliant.
- 24:10I was like, and school is going to be hard for you.
- 24:13And then you're going to get past it and you're going to
- 24:15figure and you're going to realize that you have an entire
- 24:17world of ways that you can do things that are your method, You
- 24:20know, that you could figure out your way.
- 24:22Like, unfortunately, this system is old and unfortunately, it
- 24:26hasn't adapted at all to anyone that's kind of outside the box
- 24:30even a little bit. Because I don't think because
- 24:33you don't fit into a cookie cut space that you're not brilliant
- 24:36and keep learning, keep trying to figure out your way of
- 24:38learning. And you know, and I don't know
- 24:40whether he'll ever think about it again.
- 24:42And you know, I mean, maybe he will, maybe he won't.
- 24:44But we need, I think that we definitely need more
- 24:49encouragement in general. And I've found from teaching and
- 24:52I've only been doing it for four years now.
- 24:54But that when you said, when you make it clear to the people that
- 24:57you're that you're talking to, that you know they're capable
- 25:01and you expect good things from them because you know they're
- 25:03capable, they will So rise to the occasion.
- 25:06You know, the, the the undue pressure is kind of where they
- 25:09say, hey, I don't want to deal with this right now, but I'll
- 25:11say, hey, I know that you're smart, dude.
- 25:12You know you're smart, right? He's like, yeah, I'm like, you
- 25:14think this is the best you can do is like, I don't think it's
- 25:16the best thing. OK, give me, give me a little
- 25:18bit better, you know, like that's, that's the, that's the
- 25:20way that we should be encouraging people.
- 25:22Yeah, it, you know, it's really true whether I'm working with a
- 25:26little kid for the my research or working with 18 to 22 year
- 25:30old, You know, a lot of times you do, you just need that
- 25:32reassurance that you can do this.
- 25:34And one of the things, you know, trying to get kids over, I mean,
- 25:40they're not kids. If you're 18 to 22, you're an
- 25:41adult. But you know, I'm 52, so my
- 25:45kids. But to know it's OK to fail.
- 25:49So I've learned way more by my failures than I have from my
- 25:54successes. And it's necessary.
- 25:56And learning how to pick yourself up when you've had a
- 25:59failure. In high school, I didn't have to
- 26:03study. I could, you know, take the
- 26:05test. And I did really well and, and
- 26:07everything was fine. But my first year of college, I
- 26:10figured, oh, it's just the same, right?
- 26:12You know, you're already laughing.
- 26:13I could tell you already know where I'm going then.
- 26:15So, you know, I played soccer and I was in choir and, you
- 26:19know, I took my classes and I figured I didn't need to study.
- 26:24And I learned the hard way that that is not how I'm going to.
- 26:27And I did really terrible my first semester.
- 26:30And my father was even starting to question whether or not I was
- 26:33as smart as he thought I was, which is like a huge, you know.
- 26:39The pain there. And, you know, so I had to pick
- 26:44myself up and I had to figure out how to study.
- 26:46And, you know, and I did. And, you know, I had to fight
- 26:49hard to dig myself out of the hole I got myself into.
- 26:52But, you know, I learned a valuable lesson from that.
- 26:56And that's one of the things I'm, I'm always telling my kids.
- 26:59I said, you know, I know it was way more challenging for you
- 27:02than it was for some of your friends, you know, trying to get
- 27:07through school because, you know, at a certain point, you
- 27:09know, you go from learning to read to reading to learn.
- 27:12So if you're already behind on the reading, it gets really even
- 27:14that much more challenging to learn what everybody else is
- 27:17learning. You always feel like you're
- 27:18behind. But they learned how to work
- 27:21really hard and how to not give up.
- 27:23And that perseverance that's going to take them so much
- 27:27farther. Yeah.
- 27:28Definitely, definitely learning to learn is the most valuable
- 27:32skill that you could teach someone.
- 27:34I, you know, my students whenever they complain to me
- 27:35about what does history have to do with anything?
- 27:38What does bio have to do with anything?
- 27:39Like, you know what, I'm not even going to have this stupid
- 27:43argument with you guys. I was like, you're right.
- 27:44And what I'm going to do with you.
- 27:45I was like, accepted the fact that your brain is actually
- 27:49learning a new learning process and how to you know, retain and
- 27:53understand and breakdown different forms of information
- 27:56in different ways. And I was like, even if you
- 27:57remember nothing, you will walk away a smarter, better person
- 28:01because your brain has learned how to deal with different sets,
- 28:04different ways of thinking. So hot is it?
- 28:10I actually, I'm telling my students that all the time.
- 28:12It's I, it's that it's about, you know, taking something
- 28:15complex, learning how to break it down, understanding the
- 28:18pieces and then putting, being able to put them back together
- 28:21to make sense of it and. Then they all end up making and
- 28:24then all end up popping back up into your life again at
- 28:26different points, you know, which is also really, really fun
- 28:28and really interesting. You know, I always thought I was
- 28:30bad at science until I wasn't until I was an adult and I heard
- 28:34a podcast with a good professor. You know, I, I, I was exposed to
- 28:39Angie Huberman and I listened to his episode on alcohol, which
- 28:42scared the life out of me. And then you know it.
- 28:45But, but, but the, what I, what I realized was like when I was
- 28:50in high school, I don't know if I was, if my brain was ready to
- 28:53process that type of information.
- 28:54And like I am on, I'm, I'm prepared now and I'm more and
- 28:58I'm more ready. And I, and I, and I wrote it off
- 29:00for when I was 14 for the rest of my life or 15 because of the
- 29:03rejection for the rest of my life.
- 29:05And it's so stupid as a 30 year old father that, you know, I
- 29:08shouldn't be able to look at, by, I look at, you know, basic
- 29:11biology and be like, you know, how's the food that I'm eating
- 29:13impacting my body? What's the value of exercising,
- 29:17even if I, if I don't use it for anything other than be alive for
- 29:19longer, somebody I could see my kids grow up or my grandkids or
- 29:22anything like that. So everything ends up coming
- 29:24around full circle. You want to understand current
- 29:26events, learn some history, you know, like anything ends up
- 29:29happening. And if you're, if you're too
- 29:31immature in high school to see that, that's fine.
- 29:33But you're learning and you're building those blocks.
- 29:36Yeah, absolutely. I teach statistics and you know,
- 29:41nobody wants to take an 8:00 AM stats class, right?
- 29:43It's it's usually a required course.
- 29:46It's not something you're choosing.
- 29:47Yes, how's giving the 8:00 AM is stat class?
- 29:49What's that? Your end?
- 29:51What? What's that like from your end
- 29:52giving the 8:00 AM stat class? Do you I?
- 29:54Love it. You know, can only go up, right?
- 29:58Nobody wants to be there. Everybody's exhausted.
- 30:01So if I can get them, you know, by the end of the class, if
- 30:04they're awake and they're taking in what I'm saying, then I have
- 30:07done my job. I love it.
- 30:12But I'm always just pointing out to them.
- 30:13So if you take anything away from this, I want you to be
- 30:16better evaluators of what you're consuming, whether you know what
- 30:20you're consuming in the media, what you're, you know you're
- 30:23purchasing, what you know statistical significance
- 30:27actually means. So yeah, I absolutely agree.
- 30:29Even if they never use it again in the particular context in
- 30:33which they're learning, they will use aspects of it again
- 30:36later in their life. Yeah, definitely.
- 30:38Can you tell me? I'm curious about this the new
- 30:43the lab you mentioned in passing earlier that you started from
- 30:46the ground up about and I and I wrote down notes that I don't
- 30:49know if makes any sense, but the EEG and chips interface devices.
- 30:54A professor in engineering, Yi Chen Yu, and I started years ago
- 30:59now, Brain Computer Interface lab.
- 31:02OK. There was a call for what they
- 31:06had called a think tank grant and trying to connect
- 31:10engineering with other areas of the college.
- 31:14And I had been teaching a class on brain computer interface just
- 31:19as part of a values in science and technology class, like a
- 31:22sophomore level class. And I was just thinking, you
- 31:27know, I think we could do this here.
- 31:29And I think it would be valuable.
- 31:30And I didn't know Yi Chiang at that point.
- 31:33And he got connected with me. And we're like, you know what?
- 31:37Let's just, let's just go for it.
- 31:39And then we reached out to Jonathan Walpole, who was at the
- 31:43Wadsworth Center at the time. And now he's at NCAN in Albany.
- 31:47And we said, you know, we're interested in doing this.
- 31:49Can you teach us? And it is so shocking.
- 31:53I'm always telling people, you know, just just call somebody,
- 31:57just ask, send an e-mail. I mean, the worst they can do is
- 32:00say no or ignore you. But you have, you know, you're
- 32:02no worse off now than you were before.
- 32:05And he was the greatest guy he had, he had us up there.
- 32:10We brought some students with us, taught us the basics.
- 32:13We went down and we built our own system.
- 32:16We got some data and we got an NSF grant to purchase more
- 32:19equipment and been, we've been doing this ever since.
- 32:22So with that, we use EEG electrons, cyclography to detect
- 32:28neural activity, electrical activity from the the neurons
- 32:33that are inactivated in the brain.
- 32:36And we use it actually as a trigger rather than detecting
- 32:38the signals to tell us something about brain function.
- 32:41We use the brain function to trigger an external device to
- 32:45sort of bypass your motor system.
- 32:50So. I'm sorry to just to clarify
- 32:51before you continue, just to in case it's confusing at all.
- 32:56Of course, just in case of why what you're saying is the
- 33:01opposite, how does it typically work?
- 33:03For example that it would be going vice versa, from your
- 33:07brain to the neuro to the neuro to the EEG.
- 33:10So do you remember how we were talking before about, you know,
- 33:13what something is versus how something works, right.
- 33:16So if I wanted to look at sort of neural function, I might use
- 33:22EEG to see the way the brain behaves, right?
- 33:26To see, you know, you might give a problem to two people, they
- 33:30might both get to the answer, but perhaps one has to work
- 33:34harder at it than the other, right?
- 33:36The differences and the neural activation patterns in different
- 33:39areas of the brain. Another way to use it is knowing
- 33:44what types of neural activity occurs in response to specific
- 33:48behaviors or thoughts or processes.
- 33:51We can then detect those signals and every time a signal occurs,
- 33:54it's kind of like turning the light switch on and off.
- 33:56Every time a signal occurs or goes up to a certain level, it
- 33:59triggers a device. So we ultimately we've used the
- 34:04EEG signals to fly a drone or yeah, it's really cool.
- 34:09We have it on. We have like a little YouTube
- 34:12video. Someone's brain.
- 34:14Yeah. So it's just an EEG electrode
- 34:19cap and they're basically using, we're using the neural signals
- 34:24to operate the drone and they're basically flying it around the
- 34:28gym. Get out of here.
- 34:30Yeah, that's pretty. What?
- 34:32How long you been doing this for?
- 34:35Like quite some time, I think 2010.
- 34:37So our big thing is trying to develop an EG system that's easy
- 34:42to use and affordable so it can be used outside of the lab,
- 34:45which is actually really challenging.
- 34:47Like if you have all the money in the world and all the
- 34:48equipment in the world, you can make some really cool things,
- 34:51but don't use it. So wow, you've been, you've been
- 34:58since 2010, you guys have been using neural networks to fly
- 35:06drones, to direct drones. Yeah, it's actually one of the
- 35:09things we really want to do is operate a wheelchair, yeah,
- 35:13which is harder than the drone because the drone, you know, is
- 35:16flying through the air, so there's not really a lot of
- 35:18obstacles to. Whereas when you're trying to
- 35:21navigate a hallway and into rooms and out of rooms, that's a
- 35:24little bit more challenging. So what we are aiming for is to
- 35:29create a device to operate a wheelchair for somebody who has
- 35:34a severe motor impairment, particular vigils with locked in
- 35:37syndrome, so that they can gain more independence.
- 35:41Definitely. Well, definitely.
- 35:43And I mean, I was thinking, so I guess that it's something, I
- 35:46mean, I hate to say it like this, but Neuralink kind of
- 35:49sounds trivial relative to to that, right?
- 35:52Oh, no, no, I mean, not at all. I mean, he's doing some really
- 35:54cool things with that, that, you know, the brain is really, it's
- 35:57fascinating. I'm sorry, you're right.
- 35:58So the context that I meant to say it in is the people that the
- 36:02the guys that I've seen that you guys went on different podcasts
- 36:05that use that use their eyes to play a video game like.
- 36:09It's. Like this operating a drone to
- 36:12me sounds far more real world useful and applicable and
- 36:17helpful. I would almost imagine then
- 36:20playing. I mean, not to say that one's
- 36:22not useful, the other by getting one manifests itself
- 36:24differently. And I never even I never even
- 36:26heard people talking about it before.
- 36:27I mean, how come there aren't things being commercialized in
- 36:30this sense? Oh, I'm sure they are.
- 36:36So if you're using, you know, these types of systems to play a
- 36:41video game, it's not that actually hard to actually take
- 36:45it from video game to an actual thing.
- 36:46So when we were training the student to operate the device to
- 36:51then end up flying the drone in the gym, we created essentially
- 36:56a video game to train how to do it in a virtual setting.
- 36:59And then, you know, we let them loose.
- 37:01I will say though, we tried first to fly the drone out on
- 37:05the the field, the football field, but we lost the
- 37:09connectivity, the Bluetooth right.
- 37:13So in the gym it was a more controlled environment, so it
- 37:16was easier to do. So I'm making it sound like it's
- 37:19it's easier than it probably. But that almost sounds like a
- 37:23relatively trivial problem to resolve.
- 37:26Like we're working on that could be something with Bluetooth,
- 37:28that could be something, you know, I mean, like we, we that
- 37:30that those are issues that are advancing because that's how
- 37:33society advances regardless that you can kind of just take that
- 37:36technology and reapply it to this issue, right?
- 37:38Yeah, absolutely. How much would you dedicate to
- 37:41this to this project? Well, so all my different
- 37:46research projects are sort of going on all the time.
- 37:50We always have a team of neuroscience and engineering
- 37:53students working together on this project.
- 37:56That's one of the reasons I like it so much, because it does
- 37:59bring students from different areas together to solve a
- 38:02problem. So one of the the cool, the
- 38:05coolest things, I mean, other than technology.
- 38:07Technology is awesome, but it requires the students to learn
- 38:10how to speak to each other in a way that they wouldn't normally.
- 38:14So you tend to create your own type of dialogue within your
- 38:19area of specialty, right? So you have to learn how to
- 38:22communicate with each other and explain things to somebody who
- 38:27might be a novice in one area whereas you're a novice in their
- 38:30area. So that's a huge learning
- 38:33opportunity. It actually took Yi Chung and IA
- 38:36while before we, you know, we're able to easily explain things to
- 38:40each other. Yeah, yeah, I, I picked up jiu
- 38:44jitsu about a year ago and have that exact issue and they're
- 38:47like do that I'm like, I don't know what I mean and I'm like, I
- 38:51understand and they're like, do that and I understand the words
- 38:54that are coming out of your mouth individually and put them
- 38:57together and how to translate that into doing something with
- 38:59my body. I'm like, you're going to have
- 39:02it's that it's that same issue. Yeah, that's why one thing I, I
- 39:06hope to, I, I've been, I've been working on this for a long time
- 39:09because I've been, you know, I, I, my, my, my family has very
- 39:14strong opinions. All of us are pretty different
- 39:16and all of us have pretty strong opinions just in general.
- 39:19So one thing that we risk is fighting a lot, but one thing
- 39:24that we benefit or gain from is that we really do have, we have
- 39:27learned to see things from a lot of different perspectives over
- 39:29the years because all of us growing up under the same roof
- 39:32all saw things very differently. And one thing that I did realize
- 39:36is that 90 to 95% of fights or arguments that I've ever gone in
- 39:40was really just that we're speaking two different languages
- 39:42to each other and not understanding what the other
- 39:44person was saying instead of like actually disagreeing on an
- 39:48idea like. Well said.
- 39:50Absolutely. And in the beginning, you, Chung
- 39:54and IA lot of our confusion, we were both saying the exact same
- 39:57thing. We just didn't know it.
- 39:58Yeah. So, you know, it's a process.
- 40:01My oldest loves to push my buttons and loves to argue with
- 40:05me and, and, but in all honesty, as frustrating as it is in the
- 40:10moment, we really understand where each other is coming from.
- 40:13And oftentimes we are arguing the exact same thing.
- 40:16We're just coming at it from different ways.
- 40:18Yeah, yeah, definitely. That's really cool.
- 40:20That's awesome. I love that.
- 40:22So going a little bit down the sci-fi rabbit hole, does this
- 40:28open up the world of like cyborgs and like, I mean, this
- 40:32almost sounds and you know, I was kind of freaking out about a
- 40:37year ago. It's probably has to do with
- 40:40some marijuana ingestion, but I was freaking out about the
- 40:43drone. Now we're in New Jersey that
- 40:45everyone was seeing and and then and one thing that was freaking
- 40:50me out again was, you know, the size and it didn't look like
- 40:52anyone was like, you know, they're small.
- 40:53It didn't look like anyone is was moving them around.
- 40:55And I'm like, we don't even know what that means.
- 40:57But I mean, if what you're saying is true and the science
- 41:01of this kind of stuff has been going on that we've been trying
- 41:03to work on this neural to neural to physical object connection
- 41:08for since the 2010, since the early 2 thousand 2010.
- 41:12I would imagine that the government and military could be
- 41:15developing some serious stuff with this, with this capacity,
- 41:19right? Yeah, as as scientists, we
- 41:22always have to consider, you know, what the next steps are,
- 41:26not just can we do it, should we do it, what the guard where
- 41:30rails should be. And you know, and oftentimes we
- 41:34don't always have control of all the aspects of that.
- 41:37So, yeah, I mean, it's it's always a potential problem of,
- 41:42you know, how something is going to be used and why it's used and
- 41:46being responsible and ethical use of not only the research
- 41:52you're conducting, but the tools that you're making.
- 41:54And I completely hear you. Right, right, right.
- 41:58Yeah. And I, you know, because I was
- 41:59thinking a lot about this with, with, I don't know if you were
- 42:02aware of this Anthropic and Department of War feud, but
- 42:08anthropic was looking, you know, they basically wanted to keep
- 42:10the AI safeguards on. And, and the government was
- 42:13like, Hey, like we got to do this, to do what we got to do
- 42:15with this and, and topics like we're really not comfortable
- 42:18with that. And then ChatGPT is like, you
- 42:20can do it. And are you, listen, I, I'm sure
- 42:26you can make a case, you know what you know for both ways, But
- 42:30you know, these are, these are rabbit holes that are a little
- 42:33concerning and we can't put the genie back in the bottle, as
- 42:38we've learned so many times in history.
- 42:40Yeah, that that's the big thing. You, you can't, you can't put it
- 42:43back in the bottle once you've let it out.
- 42:46And watching that whole discussion on unfold between
- 42:50anthropic and the government and, you know, and ChatGPT was
- 42:53kind of surreal because we don't, we don't often do our due
- 42:59diligence of figuring out where those safeguards need to be in
- 43:02place and holding to them when we're developing something.
- 43:06It's usually, oh, geez, we, you know, we didn't think about
- 43:09this. And it's not because, you know,
- 43:12people are inherently, you know, they're not doing their due
- 43:16diligence, but, you know, new thinking about every possible
- 43:21aspect is, you know, is a bit of a challenge.
- 43:23But once we are faced with the information and the
- 43:26possibilities, it's our responsibility to take action.
- 43:32And the regulators, and almost by definition, regulation has to
- 43:36be a step behind because you need something to regulate.
- 43:39Like, you know, there's like without Avengers used to say,
- 43:41like if there's no, like if we didn't lose to begin with,
- 43:43there'd be nothing to avenge. You know, like there's like, if
- 43:45we don't have a problem, then there's nothing, then we
- 43:47wouldn't need the government to regulate it.
- 43:50Yeah, I absolutely agree. But I think we can also
- 43:54preemptively say, you know, if we keep going in this direction,
- 43:59this is what's going to happen. And you can see a few steps
- 44:04down, you may not have realized it was going to be used for X,
- 44:07but, you know, we need to be a little bit more anticipatory and
- 44:13in terms of how we regulate ourselves and, and what are the
- 44:17potential misuses of what we're developing.
- 44:20But again, that's all that's easier said than done.
- 44:23It's easier to look back and say, oh, yeah, we should have
- 44:25noticed that it was going, you know, to go in this particular
- 44:28direction. But, you know, hindsight.
- 44:31Yeah. And the other problem is that
- 44:33people are so limited. We only look at things to the
- 44:35scope that we're used to looking at things at.
- 44:37Yes, absolutely. Absolutely.
- 44:40And we, you know, so I might look at it, I might look at the
- 44:43issue from a teaching perspective and as a dad and as
- 44:46a salesman and be like, oh, this is going to have a problem for
- 44:48me. But you're looking at it from a
- 44:50neuroscience perspective and being like, hey, like this is a
- 44:54whole nother world that we're looking at things from.
- 44:56And like, you didn't even realize what's even look out
- 44:59for. You even know what the potential
- 45:00consequences could be. Exactly.
- 45:02I, I, I hear, and that's it's always got to be a dance.
- 45:05I mean, we've seen it's a dance and it's a given play.
- 45:07It's a give and take. And it just, and I mean, I think
- 45:12that as long as we just keep, encourage good minds to that
- 45:15want to solve problems, to keep at it, we'll be, you know, I, I
- 45:20hope I'm optimistic, I'm hopeful and I have to be because I have
- 45:23kids. But you know, I mean, we got to
- 45:26do, we got to do the best we can.
- 45:28Yeah, I mean, absolutely. This is why we need to work
- 45:31together across, you know, divisional boundaries.
- 45:34We have to talk to people about what we're doing.
- 45:37We have to present our research. We have to engage people in
- 45:43conversation because others are going to see things that we
- 45:46missed. Yeah, When did you say that?
- 45:49And I noticed this too, but that people have become a little bit
- 45:53more interdisciplinary. And I've been hearing the
- 45:56sentiment these days, especially because this is really
- 45:59interesting with AI and a really interesting consequence.
- 46:02Anyone that used to be an expert on something, it's much better
- 46:07to be a generalized, you know, it's better to be a master.
- 46:10What was it? Jack of all trades, master of
- 46:13none. And I is the master of whatever
- 46:16thing that you want to dive into as deeply as you want to.
- 46:19If you want to be a very particular type of doctor, you
- 46:21want to study a very particular type of research.
- 46:25AI can help you gather and understand and understand
- 46:30information on a level that we've never had access to
- 46:34before. The example I'd like to give
- 46:35actually with recent government use was with Venezuela.
- 46:38When they, when we, when we kidnapped or took Maduro,
- 46:41whatever, whatever, whatever. What do you want to use for it?
- 46:44One thing that did that they that the government said they
- 46:46used AI for was hey, we have didn't have access to classified
- 46:50information. We gave it a stack of, you know,
- 46:53someone said, hey, give me everything we have on Venezuela
- 46:55and someone gives you and someone drops 30 billion files
- 46:57into a room and says, good luck sorting through this.
- 47:00You know that it used to be that you get a bunch of staffers, you
- 47:03get a bunch of aids, you get a bunch of people to or grad
- 47:05students or whatever it is to sit through, get them a bunch of
- 47:08pizza and have them work for a week and try to figure out the
- 47:10best plan. Now you sift through that
- 47:12information in just a matter of seconds and gather the best, the
- 47:16best Intel. And So what we're going to have,
- 47:19I think what people are going to have to learn how to do is be
- 47:21really good adept at being general thinkers, is able to hop
- 47:28around from one area to the next to the next to the next, and
- 47:30kind of be conversational across industries and across fields in
- 47:36order to really be able to keep up.
- 47:37Because AI has kind of taken all the specific oriented jobs and
- 47:41research I feel like or will be. Yeah, I mean, it's really good.
- 47:45So that wasn't a really good example where, you know, you
- 47:49have all this information and you have to coalesce this
- 47:51information and connect it. And it's a lot faster definitely
- 47:55to upload all that information into an AI engine and say here,
- 48:00I need you to sort this for X, summarize this for me or edit
- 48:05this for me. But we we definitely don't want
- 48:10to dismiss the ability of an individual and processing that
- 48:16information and finding certain keys.
- 48:20Overlook it you're. Saying yes, that, you know, AI
- 48:24might not be able to do. And I have found that it's what
- 48:28you ask and how you ask it. And, you know, you have to
- 48:31challenge the information you're getting.
- 48:33And it works really well in an area that you are already an
- 48:37expert in so that you can evaluate the information that's
- 48:40coming back. But that would be a lot harder
- 48:43to do if you were a novice in in a particular area.
- 48:47You would get that information back and you would assume it's
- 48:49right because it knows more than you do at this point, so.
- 48:53You know, that's, that's a really cool point.
- 48:55That's a really cool point. Yeah, you're right.
- 48:58I, so I use, I use Grok to help me find podcast guests, right?
- 49:02And I, I have it, I say, hey, check out my show.
- 49:05I have 100 and whatever amount of episodes and tell me I want
- 49:09to find 5 people that study history of New Mexico, right.
- 49:13And please only include people online who have their e-mail
- 49:16addresses available and it'll spit out five names for me.
- 49:18And here's some guests based on what you, what your, what your
- 49:21tone is like. And went, and then I've gone to
- 49:25and I've, and I always make a point now to Google the guests
- 49:27because sometimes they're dead, sometimes they're, sometimes
- 49:31they're convicted. Sometimes, you know, yeah, he's
- 49:33going to give me all this, all this context.
- 49:35And I'm like, I find out that this guy that it's recommending
- 49:37for me to, to interview is in jail for, you know, XY and Z.
- 49:41And I'm like, OK, well, you know, I've and, and I would have
- 49:46just given up. I would have just said, oh,
- 49:47well, you know more than I do. And I wanted five
- 49:49recommendations, so I'll take your word for it.
- 49:51So that's a good, that's a good point.
- 49:53That's a good way of thinking of it.
- 49:54I didn't think about it like. That yeah, I mean, there are
- 49:57definite advantages to using it, but knowing what the limitations
- 50:00are are key. And humans have a level of
- 50:03creativity that I think is unmatched at this point.
- 50:06Yeah, well, for now. Forever.
- 50:10I would I would love to and and it's and and I'm curious and you
- 50:14know, I mean going down the sci-fi world, brave new world
- 50:17and you know, whatever it is. I mean, if we end up, I don't
- 50:24know what, I don't know what world our kids are going to grow
- 50:27up in. I don't know what's going to be
- 50:28normal. I don't know what right now we
- 50:30have our phone that I'm at that I'm addicted to.
- 50:32I don't know what I don't know what happens if I never get my
- 50:35to turn my phone off. And it's just in my head.
- 50:37And I don't know how to, you know, and I and I can't separate
- 50:40the two. And I mean, we know that not
- 50:43that this isn't that the phone isn't necessarily healthy and
- 50:46the best for, for development and for retaining information
- 50:49and for general use. So by mixing our technology with
- 50:56our brains, I'm afraid that we won't be able to ever kind of
- 50:58turn it off and we just turn into something else completely.
- 51:01Yeah, I mean, that's one of the things that should we, I mean,
- 51:04can weigh and should weigh, right.
- 51:06So I worry about that too, because it's, you know, I have 3
- 51:11kids and they, they all have phones because, you know,
- 51:15sometimes they have after school activities and I need, and in
- 51:18this world, I kind of want to be able to get in touch with them.
- 51:23You know, processing information is very different for them now
- 51:28than it was for me growing up because, you know, we didn't
- 51:31have cell phones. I didn't, that wasn't a thing
- 51:33until I was really crushed with student.
- 51:37So that needing constant information and very short, it's
- 51:44seemingly very short attention spans.
- 51:46It's, you know, doom scrolling is not something that I had to
- 51:50contend with when I was younger. And a lot of people in my
- 51:55profession have talked about how they, you know, sort of banned
- 51:58phones from their classroom and they just, and put the computers
- 52:02away even just so that they can have a conversation and how
- 52:05great those conversations are. And it was really different
- 52:09after COVID. People sort of forgot how to
- 52:14actually have a conversation face to face with each other.
- 52:17They were still I had students sitting right next to each other
- 52:20in the lecture hall, texting each other.
- 52:24So we have to learn how to balance how to use the
- 52:28technology to our advantage without letting it take over our
- 52:32lives. Yeah.
- 52:33And losing all humanity. Yeah, for sure.
- 52:35And that was in, I mean, when I was in minutes and I was
- 52:37actually, so I was born in 95 and I was growing up just as
- 52:41cell phones were becoming pretty much ubiquitous.
- 52:44And, and I went to, I went to an all boys school for middle
- 52:51school and, but there were girls on campus just in different
- 52:54classrooms. And I found out I could text a
- 52:57girl instead of talking to her. And instead of being 10, I was
- 53:00terrified. I was terrified to look at a
- 53:02girl and talk to her. And I remember, you know, in the
- 53:04feeling of 6th, 7th, 8th grade, you know, praying and wishing to
- 53:08talk to a girl. And then I have a cell phone and
- 53:10all of a sudden it's so easy to strike up a conversation and I
- 53:13don't have to deal with any of the potential rejection and
- 53:15getting shut down. And I'm not, I would be, you
- 53:19know, socially a little bit nervous and would I would get my
- 53:22name wrong. Like I'd hesitate with my name.
- 53:24I'd stop there and you know, and I'd be like, oh, crap, I'm just
- 53:27going to give up and go home and like, I'll try again tomorrow.
- 53:30But I found out that I didn't have to deal with any of that
- 53:32discomfort. And why would why would I if I
- 53:34don't have to? And until I realized that I was
- 53:36losing out on a muscle that I really was really important to
- 53:39exercise. But I had to come to that
- 53:41conclusion myself. I had to say, I can't spend my
- 53:44whole life just texting girls what I'm going to do.
- 53:46I, you know, what am I ever going to do when it comes to
- 53:47having a real conversation or having a real confrontation or
- 53:51anything like that? Yeah, it's definitely a skill
- 53:55that, you know, people are starting to lose.
- 53:59And I also think, you know, the the anonymity of being behind
- 54:03the phone. And.
- 54:05People feel free to say things that they would never say to
- 54:09you, you know, and that's, that's problematic.
- 54:14You know, we, we don't talk to each other anymore and we
- 54:18sometimes lose the positive aspects of, of human connection.
- 54:24And I would love to see that come back a little bit more.
- 54:26I think it will. I think it will.
- 54:28I think that I think that there are certain indications that
- 54:31that it's going to and I think that this was, I think that
- 54:34whatever mass experiment social media was for the amount of time
- 54:37that it that it was this kind of experiment, people are realizing
- 54:41on the map. Like people are seeing how
- 54:42unhappy a lot of people have been in the last 10-15 years and
- 54:46they do want to change. Like one thing is like, that's
- 54:49amazing how humanity is that generations come and go fast.
- 54:53And I think we realize and we learn from each other.
- 54:56You know, like I learned from my parents things to and not things
- 55:00to do and not to do. And my kids will certainly learn
- 55:02from me things to do and not to do and we'll correct.
- 55:04And well, you know, and I think, and I really think that people
- 55:07see that relationships are at all time low.
- 55:09Loneliness is at all time high for everyone.
- 55:12You know, women don't, guys are afraid to ask girls out on dates
- 55:15and go, you know, and, and, and, and just, I mean, no one knows
- 55:18how to have relationships anymore.
- 55:20And, and then kids are saying, Hey, screw that.
- 55:23I don't want to be a part of that.
- 55:24And you know, if, if, if everyone says that this is
- 55:27social media doing it, then, you know, then I'll put it away for
- 55:30a day a week, you know, a couple of times a week, or I'll leave
- 55:33it at home instead of taking it to school or whatever it is.
- 55:36But I think I, I, I, I am hopeful in that in that sense, I
- 55:40do want to actually talk to you also.
- 55:42And hopefully you know, this will be the last fun part of the
- 55:45whole thing's been fun, but the last fun part of our
- 55:47conversation is music in the brain.
- 55:51I love music. Music means everything to me in
- 55:56so many different capacities. I love music for the music,
- 55:59which I've only learned to recently appreciate because I
- 56:02started playing guitar. I used to listen to music for
- 56:05the lyrics as opposed to, you know, as opposed to just for the
- 56:08music. So I'd focus more on the
- 56:10singer-songwriter and simple, simply simply musically
- 56:14structured music. And I found that they've
- 56:19actually served very different, as very different tools in my
- 56:23life depending on what I'm going through for different things to,
- 56:27you know, for me, you know, sometimes I need more lyric
- 56:29based, story oriented narrative to get me through whatever I'm
- 56:34experiencing. And sometimes I do need music,
- 56:36like just the music and just the sounds and just the melody and
- 56:39just the interplay between the, between the band members.
- 56:44What how'd you get started on this and what you know and and
- 56:47how do you go about studying and what do you study as far as
- 56:50music in the brain? Yeah, it's a really interesting
- 56:53question because again, it's it's really broad.
- 56:56And I started teaching a class called Music in the Brain with a
- 57:01music professor. Her name's Jennifer Kelly, and
- 57:04she and I really want to teach a class together.
- 57:06And so we decided that we would bring, you know, neuroscience
- 57:11and and music together. And there's so many different
- 57:14ways you'd come at it. And it's really interesting that
- 57:17you were talking about lyrics versus the melody and the tempo
- 57:20and what's more important to you at a particular time.
- 57:23And when we would talk about music, and again, we're both
- 57:25coming at it from really different directions, she was
- 57:27really adamant that when we were focusing on music, we were just
- 57:30focusing on the more instrumental component and not
- 57:34the lyrics and how the lyrics could interfere with your
- 57:38appreciation of of the music. And I didn't, I didn't see it
- 57:44that way because that's not how I was.
- 57:46I was coming at it and our class was very different.
- 57:51So she would teach, you know, about music and music
- 57:54appreciation, and I would teach about the brain.
- 57:57And then we would have to bring these two converging ideas
- 57:59together to meet the needs of both of our students, both the
- 58:03neuro students and the music majors.
- 58:05And one of the things that I was really fascinated about was this
- 58:11neuroscientist and musician. His name is Charles Lim and he
- 58:17found a way to study creativity. So studying creativity in the
- 58:20brain is a really hard thing to do because how do you define
- 58:23creativity? How to find it?
- 58:26How do you define it? Define it.
- 58:28I would say, I would say free flowing personalized
- 58:32associations. OK, great.
- 58:34So, you know, as a scientist, you really have to define all
- 58:37your parameters. You have to study, you know,
- 58:40something very specifically. So sometimes by defining the
- 58:44parameters, you can sort of take the creativity out of
- 58:46creativity. But he studied the changes in
- 58:53neural activation patterns using functional magnetic resonance
- 58:56imaging and jazz so had. Improv music for the most.
- 59:02Yeah. So we had them play a structured
- 59:05component and then a more free flowing component and looked at
- 59:09the the activation patterns in the brain.
- 59:11And I just thought that this was just that in itself was super
- 59:16creative and fascinating. And I was also really interested
- 59:21in the use of music at in therapy.
- 59:25Yeah, so using music and the tone and the pacing of music to
- 59:30help people with motor impairments or help people who
- 59:34had lost their ability to speak for whatever reason, to actually
- 59:38sing the lyrics even though they couldn't sing the words, as
- 59:41opposed to speaking the words and how that can be used to sort
- 59:45of bypassed areas of damage. So when we taught this class, we
- 59:51used music to express emotion. One of the things I find
- 59:57fascinating is I used an example of, you know, the Halloween
- 1:00:01movie where the pumpkins sort of getting closer and closer to
- 1:00:04you. Yeah, you turn the music off.
- 1:00:07Yeah. Totally not scary.
- 1:00:09Sit all the time. You have the music on, you know,
- 1:00:14your heart rate starts and your galvanic skin response and you
- 1:00:17know, your hands start sweating. The music is such a powerful
- 1:00:21influence over our emotions and our movement and you know.
- 1:00:26Breathing even and our breathing.
- 1:00:28I've noticed that with, with tense movies, I, I, I, my
- 1:00:31breathing slows down right before something really scary
- 1:00:34happens. And if I'm scared, I force
- 1:00:36myself to take deep breaths while while I watch the horror
- 1:00:39movie that I that I'm being forced to watch.
- 1:00:43But and then the music in that is like a whole nother character
- 1:00:47to the movie outside of the actors, right?
- 1:00:49It helps to elicit those emotions.
- 1:00:52And I find all of that really fascinating.
- 1:00:54So This is why we want to teach that class.
- 1:00:57Actually, I had some students I haven't been teaching the last
- 1:01:00couple years because I was Dean for a few years and I'm on
- 1:01:03sabbatical right now. And a student said that they
- 1:01:06were graduating next year and I really needed to teach that
- 1:01:09class. So I'm, I'm hoping to, but
- 1:01:13again, it's one of those classes that I think is better taught
- 1:01:16when you have people who are experts in two different fields
- 1:01:19and you're bringing those together rather me trying to
- 1:01:22just teach it all by myself. Totally.
- 1:01:24That's really, really cool. That's I never even heard of
- 1:01:27collaborative classes like that. I've never taken any in college
- 1:01:29at least It's really. Cool.
- 1:01:31They're the most challenging to teach from the side of a
- 1:01:34professor, but they're the most interesting.
- 1:01:37It's actually twice the amount of work as opposed to half the
- 1:01:40amount of work, but I think they're the most most
- 1:01:42interesting for students. I bet, I bet that's really, it's
- 1:01:45really awesome. I I'm also curious and there's
- 1:01:49so much to go into, at least from what we, the brief, the
- 1:01:52brief, the brief overview. But first of all, I'm also
- 1:01:57curious about the relationship between lights and music because
- 1:01:59I know that, for example, when and I've gone to some concerts
- 1:02:04where, you know, I've listened. So I'm actually much more
- 1:02:07nowadays into the improvisation improv provisional, thank you
- 1:02:15Grateful Dead and and strings and like that whole that whole
- 1:02:19genre of music. And one thing I didn't notice
- 1:02:22I've noticed is that when I've gone to see shows, cover shows
- 1:02:25or real shows, an enormous component Fish, which is a
- 1:02:28famous jam band from your neck of the woods to play around
- 1:02:31there. They they're they're light sky
- 1:02:35is known as a six member of the band because or the 5th member
- 1:02:37of the band because it the lights are so integral to the
- 1:02:40audience experience during the concert.
- 1:02:42And there's something about when music is playing that activates
- 1:02:45another part of your brain that and it's so interesting because
- 1:02:49songs almost feel like they take like they have color tones to
- 1:02:52them. So if like if you're playing a
- 1:02:54song and then the and then the and then the whole place flashes
- 1:02:57red. There's something about like the
- 1:02:59relationship between the tone of the music and the color that's
- 1:03:02being flashed, you know it across the room and it enhances
- 1:03:07the experience to a tremendous degree.
- 1:03:10I mean, I, I can't even compare listening to that kind of thing
- 1:03:13even on great speakers at home and then being there with the
- 1:03:15crowd with the lights flashing like that.
- 1:03:17I'm curious if there's if you if you've noticed any overlay
- 1:03:20between the two. You know, that's really
- 1:03:22interesting. And I've never studied the
- 1:03:24interplay between. So in this case, like your
- 1:03:28emotional connection to the music with, you know, what's
- 1:03:33being presented visually and what's going on in the brain.
- 1:03:37So I haven't actually studied that.
- 1:03:39And, you know, when we're studying something, the more
- 1:03:41variables we put into the mix, sometimes the more limit them.
- 1:03:47But now that you said that, now I'm actually curious and I I
- 1:03:51want to go look and you know. Get some, get some, get some
- 1:03:54funding and go to the sphere in Vegas.
- 1:03:56You can check out over there I mean.
- 1:03:59Experimental Lab. Real Life.
- 1:04:01Experimental Lab and you and there is no, there's no venue
- 1:04:05like this fear and it's, and it's so immersive.
- 1:04:07And I mean, I don't know if you've ever seen any videos of
- 1:04:09it, but oh, man. I mean, and I mean, I don't know
- 1:04:13what kind of music you listen to, but just about most great
- 1:04:18bands have, you know, like a band that you will certainly
- 1:04:21appreciate has played there where you can kind of see the
- 1:04:23way they make use of, of, of everything.
- 1:04:25And you know, we know that music also turns on the, the visual
- 1:04:29aspect of our brain too. I I do a creative writing
- 1:04:32assignment with my students who I'll play a well play a score,
- 1:04:36I'll play an instrumental piece and have them write the image
- 1:04:39that pops up in their head from the music.
- 1:04:42Yeah. And there's sometimes where it's
- 1:04:44remarkable how 10 students or 15 students can all come up with
- 1:04:49extremely similar themes from music.
- 1:04:51And you wonder, you know, is it is that just association wiring?
- 1:04:55Like, you know, the pirates type of fat pirates in the Caribbean
- 1:04:57theme? Like everyone recognizes that
- 1:05:00that's going to be pirate music, right?
- 1:05:01But what if there's music that's a little bit less well known?
- 1:05:04And then one person thinks it reminds them of a field, another
- 1:05:06person thinks reminds them of an old French villa.
- 1:05:09You know, I mean you, you, you know, So I've had a lot, a lot
- 1:05:12of fun tinkering around students perception of music too, and
- 1:05:14it's really cool. Yeah, usually, you know, so when
- 1:05:17I teach introduction to neuroscience class, I'll take a
- 1:05:21song that was, you know, very popular over the summer,
- 1:05:25whatever song that may be, and I'll play a clip from it.
- 1:05:28And I just tell the students, just just free, right, right,
- 1:05:30whatever comes to your mind. And then we talk about all those
- 1:05:33different aspects, and it helps me to introduce the idea that
- 1:05:36although there are parts of your brain that are responsible for
- 1:05:39vision and auditory, your brain is all interconnected, right?
- 1:05:43So it's the circuitry that ultimately gives us this sense
- 1:05:48of connectedness between visual and auditory and, and movement
- 1:05:52and so on and so forth. And it's that part of the brain
- 1:05:55that really fascinates me. Yeah, I have a friend and maybe
- 1:06:00you could speak to this. I have a good friend of mine who
- 1:06:02has, I mean, he's very good about it, but he has a little
- 1:06:05bit of a stutter. And one of the ways that he
- 1:06:07deals with it is if he catches himself stuttering, he'll kind
- 1:06:11of slow down on that word. So if he was going to stutter on
- 1:06:14the West of the word, it's a, it's this herd that I'm having a
- 1:06:19hard time with. He does rap and he is an
- 1:06:23excellent rapper and he is incredibly creative and he has
- 1:06:27no problems just freestyling and coming up with that.
- 1:06:32Can you speak to the, you know, is it the beat that's doing it?
- 1:06:36What's happening with the stutter that is that that or I
- 1:06:39guess I don't know if you could speak about his particular case,
- 1:06:41but in general what happens? Yeah, you'll even hear about.
- 1:06:45So something about the beat and the music has been very helpful
- 1:06:51in a lot of different aspects. So somebody with movement
- 1:06:55disorder might use music and might dance fluidly, but then
- 1:06:58when the music stops, when they have, you know, when they lose
- 1:07:02that thing to attach to, to help preempt the next motion, now
- 1:07:09they might lose their ability to move as fluidly.
- 1:07:12Or somebody with Tourette's syndrome might use excuse.
- 1:07:17Me Billie Eilish has Tourette's syndrome, apparently.
- 1:07:19I didn't know about that. Yeah, and she and she's talked
- 1:07:22about how music has helped her, has helped her navigate her way
- 1:07:24through it. Yes, yes, there is an excellent
- 1:07:28movie. I think it's called The Tick
- 1:07:29Code with and it's about a little boy who has Tourette's
- 1:07:34and how he's a musician and he connects with another musician
- 1:07:38who also has Tourettes that he didn't know about.
- 1:07:40And and how music helps with their, you know, to control
- 1:07:47their motor ticks and help them, you know, connect with
- 1:07:50something. It's music is really powerful
- 1:07:54and we haven't even scratched the surface, I don't think.
- 1:07:57And all you know and the power it actually holds.
- 1:08:01I think we've written an oath as an art instead of looking at it
- 1:08:04at the science. Yes, I would absolutely agree
- 1:08:07with that. And yeah, it feels a little bit
- 1:08:10like a shame that we that we do that because we, I mean, we even
- 1:08:18know the impact of there have been so many times in my life
- 1:08:22where I felt the weight of the world, you know, when I was in
- 1:08:25my early 20s and I had no idea what I was going to do with
- 1:08:27myself. And I and everyone around me
- 1:08:29felt like they had everything worked out and were moving on
- 1:08:31with their lives. And I didn't.
- 1:08:32And then they were. And I would just RIP down the
- 1:08:35highway and listen to music and like, that was the only thing
- 1:08:38that was going to, you know, help me at that moment or set me
- 1:08:41free at that moment. Bruce Springsteen has saved my
- 1:08:43life, saved me many times throughout the years, you know,
- 1:08:47but but there's something about like, like there's something
- 1:08:52interesting about the fact that, hey, if I'm down, listening to
- 1:08:55happy music doesn't necessarily work to pick me up.
- 1:08:57Sometimes I have to listen to sad music when I'm down.
- 1:09:00And then I'm like, Oh, now I'm better, you know, and, and what
- 1:09:03is that and why and why do we feel that way?
- 1:09:05And that's a science too, you know, that that should be
- 1:09:07something that we should be employing and using.
- 1:09:09My first podcast, one of my first real guests, the quote UN
- 1:09:12quote that you could say was actually some, I believe she's a
- 1:09:17nurse or a therapist down here in South in University of Miami.
- 1:09:21And she's a music therapist and she uses the ukulele and the
- 1:09:26piano and she uses it to help student.
- 1:09:28She uses it to help in all sorts of fact faculties and with all
- 1:09:32sorts of patients. I think primarily with the youth
- 1:09:35with kids, but they've been expanding the program and she's
- 1:09:38like, we can't even hire enough music therapists is how popular
- 1:09:41and how useful it's been. So I hope that there's an
- 1:09:44industry that keeps on taking off.
- 1:09:45Me too. OK.
- 1:09:47What are so to wrap up, what are a couple of things that you're
- 1:09:50looking forward to that you're that you're I guess hopeful for,
- 1:09:53I guess or excited about and when some of the things that you
- 1:09:56were a little nervous about that you would like to at least
- 1:09:59people to bear in mind? In terms of science or just life
- 1:10:03or. Yeah, whatever you think is
- 1:10:06important. You know, so I always, I always
- 1:10:10go to my kids first. I'm, you know, curious what life
- 1:10:14is going to be like for them and whether I've prepared them
- 1:10:17enough to meet all of those challenges.
- 1:10:19And, you know, they're incredible people.
- 1:10:22And although they're all my kids, they're all, you know,
- 1:10:25very different. So, you know, I'm interested in
- 1:10:29in what the world is going to be like for them and how they are
- 1:10:33going to contribute to it. In my field.
- 1:10:38I would love if, you know, the tool that we developed through,
- 1:10:42you know, decades of science actually helps somebody what
- 1:10:47that be the BCI or whether we're able to detect reading
- 1:10:52impairment so that kids can get help as soon as possible.
- 1:10:56I would love to be able to, you know, give it forward to have a
- 1:11:01positive impact on others lives. Definitely, definitely.
- 1:11:04Well, Doctor Lisa Gable, thank you so, so much for coming.
- 1:11:08This is so much fun. I hope you had fun with the
- 1:11:10second podcast experience. You were excellent.
- 1:11:13And and I hope to do this again because this is so much fun.
- 1:11:16And when you have some exciting new things, you can let me know.
- 1:11:20I'll check back in. But I'm really, I think this is
- 1:11:23a lot of fun. I'm really excited.
- 1:11:24I hope to. I hope to stay in touch.
- 1:11:26Thank you for having me, I really appreciate it.
- 1:11:27It's a blast. Take care.
- 1:11:28Bye bye. OK.
- 1:11:30What do you think? That was fun.
- 1:11:33I just realized that I had like.