1061-Raf Kinase Complexes Regulating Proton Pump Activation
Researchers have identified a vital regulatory mechanism for plasma membrane proton pumps that is essential for plant development and environmental responses. The study reveals that C5-Raf and C7-Raf protein kinases cooperate to form a heterocomplex that activates these pumps by phosphorylating a specific site known as Thr881. This molecular pathway is highly conserved across various plant species, ranging from ancient liverworts to modern flowering plants. In the model plant Arabidopsis, specific kinases like Raf36 and HT1 direct this process to control overall growth and the opening of…
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