Latest / The Smart Cookies podcast / Are we on the verge of LIVING FOREVER? With dr. Ariel Zeleznikow - Johnston
Transcript
- 0:00Dr. Ariel Zalesnikov-Johnston is a neuroscientist, currently a research fellow at Monash University
- 0:10in Australia and the author of the outstanding book, The Future Loves You, How and Why We
- 0:16Should Abolish Death.
- 0:17Ariel, welcome to the show.
- 0:20Thanks very much for having me.
- 0:21Well, just what a thoroughly enjoyable and thought provoking book.
- 0:26So much to talk about, but I thought it would perhaps be best if we begin this conversation
- 0:31with a story that features in The Future Loves You and that's the Elizabeth Hughes story.
- 0:38Why is she relevant?
- 0:40Yeah.
- 0:41So, the book, in very brief, and we'll get into it, is about medical progress and the
- 0:47possibility of being able to live just long enough that a treatment is developed so that
- 0:52one can live longer.
- 0:54In the case of the book, I'm talking about weird sci-fi stuff like brain preservation
- 0:59and mind uploading and that sort of stuff.
- 1:01But I think to start off with, it's worth thinking about the development of medical
- 1:06treatments we take for granted today that once upon a time were themselves science fiction.
- 1:12So I start this book with the story of Elizabeth Hughes, who in 1919, at the age of 11, was
- 1:21diagnosed with what was then called juvenile diabetes.
- 1:25And at the time, there was no insulin.
- 1:27We didn't really know what caused diabetes and the prognosis, the survival for someone
- 1:32in her circumstance, was only a few months.
- 1:35So basically everyone else who developed diabetes died shortly thereafter.
- 1:42Now Elizabeth's parents were understandably very upset at this prospect and they weren't
- 1:48looking for anything they could do to try and help save their daughter.
- 1:52Now they didn't come across insulin because it hadn't been discovered yet, but what they
- 1:56did come across was one weird and new therapy that had been invented, which was starvation
- 2:02therapy, which was the practice of taking diabetic children and feeding them only just
- 2:08enough food so that they didn't starve to death.
- 2:11But in doing so, reducing the ill effects of having too much sugar in the blood, which
- 2:17is what happens in diabetes, and thus stopping things like getting acidic blood and other
- 2:22complications of diabetes.
- 2:24So Elizabeth was kept in this starvation-like state, just teetering on the edge of being
- 2:30alive.
- 2:31But as a result, instead of dying after a few months, she lived for a few years in this
- 2:36way.
- 2:37And then in 1921, when insulin was discovered and did become available, she was able to
- 2:42receive it and then gain back her weight, gain back her health, go on to go to university,
- 2:49to get a job, to have kids, and live into her 70s.
- 2:53So as a result, it's incredible, this progress that she just lived long enough to make it
- 3:01so that she could make use of this new technology.
- 3:04And I think it's a good example of how unprecedented circumstances, somebody suddenly not dying
- 3:13from a disease that up until that point killed everyone who had it, sometimes things really
- 3:18do change.
- 3:19So would you say that, I mean, I guess that's what you're saying, that we're at the precipice
- 3:23of a similar kind of event when it comes to, I kind of don't want to say immortality because
- 3:29it makes me feel like we're discussing Highlander or something.
- 3:32But yeah, in a way, abolishing mortality.
- 3:35Well, yeah.
- 3:37So I mean, immortality is a big term and I avoid using it because obviously, I don't
- 3:42think there's any proposal anyone has that could make someone be totally immune to the
- 3:47forces of destruction that exist in the world, whether that's car accidents, whether that's
- 3:52nuclear war, whether that's the eventual heat death of the universe.
- 3:55Like, there's plenty of things out there that can get someone.
- 3:59But what I think is relevant from the Elizabeth story is it's an example of somebody surviving
- 4:05long enough to make use of newly developed medical treatments so that they could then
- 4:10live longer into the future.
- 4:13And what I talk about in my book is the prospect of maybe being able to take people who are
- 4:18dying today and preserve them in some way, shape or form, such that they're able to be
- 4:23revived in the future once future medical advances can fix whatever it was that caused
- 4:29them to be dying in the first place and restore them to health that way.
- 4:33And hopefully through doing so, give them considerably more time, as much time as is
- 4:38practical and as that they would want to take up.
- 4:41Okay, let's just jump right in.
- 4:44How would preservation work?
- 4:46What's the idea or the mechanism behind this process?
- 4:49Yeah.
- 4:50So weird sci-fi idea, right?
- 4:52Like people have probably come across it in movies or books, this idea of taking someone,
- 4:58putting them in a cryopod or stasis or something where they're unconscious and unchanging for,
- 5:05I don't know, some duration of time, a year, 10 years, a century.
- 5:09And then at the end, they come out and they're like basically the same as when they initially
- 5:13went in.
- 5:14That's the notion in science fiction.
- 5:16But the question I wanted to ask with this book is like, is anything like that actually
- 5:20possible?
- 5:22And if it could be made possible, like what would be real and what is hype and what would
- 5:26the constraints be?
- 5:28That's the set of things that I work through over the course of the book.
- 5:33So it's a science fiction idea, but it does have some precedence from the natural world.
- 5:40So we see, for example, there's a kind of frog called the wood frog that lives in the
- 5:44Arctic.
- 5:46And each winter, most of its body freezes, its heart stops, its brain activity stops,
- 5:52but then come spring, it thaws out and it goes back to hopping around.
- 5:56So that's one example of how something like this works.
- 5:59Or another example, even with human biology that we use today, is the sort of preservation
- 6:06methods we use for storing sperm and eggs and embryos that are used in IVF procedures,
- 6:14where what happens is you can take these groups of cells or individual cells and you can cool
- 6:19them down to really low temperatures and through doing so, essentially stop biological and
- 6:25chemical time.
- 6:27What's fascinating about that is the technology to do that has improved quite a lot over the
- 6:32past few decades as well.
- 6:35So initially, people tried naive ideas of just like straight freezing biological material,
- 6:40just like cooling it in liquid nitrogen.
- 6:42And that kind of worked, but it causes some problems where just straight freezing causes
- 6:48ice formation.
- 6:49So you get these crystals forming, they can damage the cells, they can dehydrate cells.
- 6:54It's not so good.
- 6:56So better techniques that have been developed are those that use something called vitrification,
- 7:02where essentially what you do is you add some antifreeze or cryoprotectants to things before
- 7:07you cool them down.
- 7:08And through doing so, you prevent the formation of ice and you can get better survival rates
- 7:13for embryos and other material that gets stored.
- 7:18Now that works really well for small amounts of biological material, like embryos and sperm
- 7:23and eggs.
- 7:24But the problem is it doesn't scale so well as you get to bigger and bigger things, whether
- 7:28that's organs or whether that's whole human bodies.
- 7:31And that's because the cryoprotectants, the antifreeze itself can be a little bit toxic,
- 7:37but also it can cause dehydration.
- 7:40So if you look at the brains of people who've been preserved using vitrification techniques,
- 7:46you'll see that they've shriveled by something like 50%, which is really not ideal for a
- 7:51procedure that's supposed to preserve someone fully intact with the hope of being able to
- 7:55revive them in the future.
- 7:58But that's not the last technique that's been developed.
- 8:01And the one that I am most bullish about is a newer technique called aldehyde-stabilized
- 8:06cryopreservation, which is a big mouthful.
- 8:09But basically it's a technique that involves something called fixation.
- 8:12So the idea here is before you cool down a person's body, you can use preservative chemicals
- 8:19that you introduce into them, fixatives.
- 8:22And what they do is they infiltrate someone's body, they get everywhere, and they essentially
- 8:27lock everything in place, like all the molecules, all the structures down to the nanoscopic,
- 8:33microscopic level.
- 8:35And in doing so, they prevent any decay of the synaptic neural connections that store
- 8:40someone's memories, personality, all those sorts of structures.
- 8:45And they ensure that everything that's critical to making a person who they are, all those
- 8:50structures, all that information, stays intact for an indefinite period of time.
- 8:56So that's the short, well, the long answer, I guess, to what techniques we're talking
- 9:01about when I talk about preserving individuals.
- 9:03Okay, just so I imagine this better.
- 9:06So you say with this technology, I'm not going to be able to repeat it, we can preserve our
- 9:10brains, right?
- 9:11So let's say a person is terminally ill and wants to proceed with this procedure.
- 9:15What happens next?
- 9:16Do they need to remove the brain and put it in some sort of a vat with these chemicals?
- 9:21No.
- 9:22Or do they just freeze the whole body like they did with the 60s or whatever?
- 9:26Yeah, no, I'll run you through it.
- 9:28So I go through this at length in the book, and the short version is what you would do
- 9:33is you would take someone who's terminally ill.
- 9:35Now, in most jurisdictions, you'd only be able to do this procedure from once their
- 9:40heart stops and they were legally declared dead.
- 9:44But at the point where someone's just after someone's heart has stopped, what you would
- 9:47do is you would insert a catheter, essentially a big needle, into their heart, and you would
- 9:53then drain, wash out the blood from their body and introduce these fixative chemicals
- 9:58instead.
- 9:59So this would permeate throughout their body and their brain, their entire circulatory
- 10:06system.
- 10:07And in doing so, the preservative chemicals would get everywhere and lock everything in
- 10:11place in that manner and ensure good quality preservation.
- 10:15What you could then also do is once you've got the fixative in place, you could then
- 10:19introduce some antifreeze cryoprotectants.
- 10:24And because you've done this initial fixation, you won't get the associated dehydration
- 10:28after.
- 10:30And that means you can then also store people at cold temperatures if you want without having
- 10:34to worry about those issues as well.
- 10:36It sounds really gruesome.
- 10:37I understand that.
- 10:39But I assure you all surgery sounds really gruesome once you start talking about the
- 10:43technical details.
- 10:46But you said the heart needs to stop beating in order for us to be able to do that legally.
- 10:53Wouldn't that defeat the purpose?
- 10:54Because that would mean that you have to be dead first.
- 10:56So this gets into the definition of what exactly death is, which is also a fascinating aspect
- 11:02of this whole set of philosophical questions.
- 11:05And I think what really helps is a bit of a historical perspective when trying to keep
- 11:09in mind what it means for someone to die.
- 11:13Because it can seem really clear cut and like we're always sure that doctors and lawyers
- 11:18and ethicists have a clear idea of when someone's alive and when someone's dead.
- 11:22But if you look at how the definition has changed over history, you can see it's actually
- 11:26much murkier.
- 11:28So prior to the middle of the 20th century, doctors used to define someone dead just based
- 11:35on their stopped breathing.
- 11:37Because before that point, there wasn't really anything you could do for someone anymore
- 11:41once they'd stopped breathing.
- 11:43But then with the invention of things like mechanical ventilators, things that could
- 11:47breathe for people once their lungs had stopped, or cardiopulmonary bypass machines, machines
- 11:53that could circulate someone's blood after their heart had stopped beating, it became
- 11:58clear that a definition of death just based on someone stopped breathing wasn't really
- 12:03going to cut it anymore.
- 12:05So in the 1970s in the US, there was the development of a new definition called, sorry, there was
- 12:13a new law developed called the Uniform Determination of Death Act.
- 12:18And what it did is it defined someone is dead based on one of two criteria, either one,
- 12:24irreversible cessation of all heart and lung functions, or two, irreversible cessation
- 12:32of all functions of the brain.
- 12:34Now that was better than the previous lack of any formal definition.
- 12:39But even at the time, it became apparent that there were issues with this newer definition.
- 12:44The first issue being that the technology for keeping someone alive even when their
- 12:49heart and lungs had stopped was continuing to get better and better.
- 12:53And nowadays we use something called ECMO, or extracorporeal membrane oxygenation machines,
- 12:59that are essentially able to fully substitute someone's heart and lungs for a period of
- 13:04days or weeks by taking the blood out of someone, removing the carbon dioxide, introducing the
- 13:10oxygen back into the blood, and then returning that blood back into someone's body.
- 13:14So that's why nowadays we don't really think about heart and lung function being critical
- 13:19to a person being alive.
- 13:21We're much more focused on the brain functions aspect, which is the definition of brain death.
- 13:27But the issue with the brain death one as well is that in the same way that we've gotten
- 13:31better and better at developing technology, which can replace the functions of someone's
- 13:37heart and lungs, we're slowly getting better at doing the same technology for replacing
- 13:42damaged brain functions.
- 13:44So there's examples where people have had spinal cord injuries and they've been given
- 13:48implants that can give them some control over their limbs again or some control over their
- 13:53blood pressure.
- 13:54And there's newer fancier implants that are helping people with language difficulties
- 13:59or other kinds of motor difficulties.
- 14:01And these prosthetics are continuing to improve.
- 14:05So the question is, if these things continue to evolve, if we continue to replace more
- 14:10and more damaged brain functions with machines, then what will it mean for someone to die
- 14:16based on a definition of loss of brain functions if you can just always replace brain functions?
- 14:24And what some philosophers have said is that actually what we really care about when we
- 14:29talk about a person being alive or having died is not whether they can grow their nails
- 14:34or beat their heart.
- 14:36It's whether they still have their memories, their personality, their goals and desires,
- 14:41all the psychological properties that make them them.
- 14:44That's what's important to still being alive.
- 14:47So to bring this back to your question about someone's heart stopping.
- 14:50So already at the moment, there's frequently circumstances where people survive having
- 14:54their heart stopped for a period of time.
- 14:58But we can legally define someone as dead once their heart is stopped.
- 15:03But we can do so even while their brain and all the structures in their brain that give
- 15:08them their psychological properties are still intact.
- 15:11So that's why I distinguish between the legal definition of death and what I think is actually
- 15:16the philosophically correct definition of death.
- 15:19Wow.
- 15:20Okay.
- 15:21If we take this process further like you do in the book, how would our descendants in
- 15:26the future, if they choose to do so, then revive or reproduce this kind of hibernating mind?
- 15:33Yeah.
- 15:35So that's a great question and obviously a speculative one.
- 15:39I try and stay mostly as grounded as I can in modern neuroscience, modern medicine.
- 15:44But when we're looking to the future, we've got to have some guesses about what might
- 15:47happen.
- 15:48That's not to say I think it's complete guesswork and that there's nothing that can inform what
- 15:52I'm saying.
- 15:53Just to say that I am cautious when I'm guessing at what might be possible.
- 15:58So that being said, there's two main ideas people have in mind when it comes to future
- 16:02revival.
- 16:03One is mind uploading, the idea of taking someone's brain and somehow giving them a
- 16:10new artificial digital format based on the original biological brain.
- 16:16And the other version is just fixing the brain and body that the individual had directly
- 16:21through maybe some kind of nanomedicine or just much more advanced medicine than we have
- 16:25today.
- 16:26Sorry, if I can interrupt just for a second.
- 16:27In the first option, do we mean like they just upload you into some sort of a very detailed
- 16:32and advanced version of Minecraft or something?
- 16:36So yeah, let's get into the details.
- 16:38So there's all sorts of different ways you can imagine something like mind uploading,
- 16:43giving someone a new digital electronic brain could work.
- 16:47So I was talking before about the brain implants and prostheses that people have been given
- 16:52where for example, they have loss of a limb and they get an implant which can help them
- 16:57control a limb.
- 16:58Or when they have a bit of their brain is damaged that they get given some implant that
- 17:01can replace what its functions were.
- 17:04You can imagine taking this to its logical extreme where you have a digital electronic
- 17:10version of a brain that perfectly recreates the previous functions of the biological brain
- 17:17on which it was based.
- 17:18So that would be called a whole brain emulation.
- 17:21Where what you've done is you've looked at all 86 billion neurons that make up some human's
- 17:27brain and you've looked at all of the roughly quadrillion connections that exist between
- 17:33those neurons, those synapses, and then you've recreated them in some format.
- 17:38Now that might be just digitally or virtually inside standard computing hardware that we
- 17:43think about in the memory of a hard drive or it could also alternatively possibly be
- 17:48in what's called a neuromorphic format.
- 17:51So that's a kind of still digital electronic format but where the hardware is much more
- 17:56similar to what we normally think about with biological brains.
- 18:00But either way, you've taken the biology, you've scanned someone's brain at very high
- 18:05resolution, you've used that information to recreate their brain, and then you have to
- 18:10connect it up to some sort of sensory inputs and outputs, whether that's a robotic body,
- 18:15whether that's a virtual body, something that can give them back their vision and their
- 18:20taste and their feeling of having a body.
- 18:23That's the coarse-grained idea of what people have in mind when they're thinking about uploading.
- 18:29Okay, this is all speculative, of course, but if we upload my personality and my memories
- 18:35and then upload it and bring it back online sometime in the future, wouldn't I just be
- 18:40a clone then?
- 18:42You know what I mean?
- 18:43Would that still feel like me?
- 18:45Yeah, it's not obvious that that would be you, right?
- 18:50I share that intuition as well.
- 18:52But what I would say is when you take a step back, what it is that makes someone the same
- 18:56person over time ends up being pretty weird and complicated.
- 19:00And you can prompt this intuition almost immediately by considering the fact that you're not really
- 19:05even made of the same stuff that you were a few years ago, nor will you be made of the
- 19:10same stuff in a few years from now.
- 19:13So about every year and a half, you fully replace the or almost entirely replace the
- 19:19physical material of your body through eating and drinking and breathing and having your
- 19:24cells change over, all this material change over.
- 19:28So the question is, what is it that makes you the same person today that you were a
- 19:32year ago, five years ago, 10 years ago, or will be in a few years from now?
- 19:37That's the question of personal identity.
- 19:41And what's interesting is that the question of personal identity comes apart from the
- 19:44question of what is it that makes you who you are in any given moment?
- 19:49So when you're conscious right now, when you're sitting at this computer talking to me, feeling
- 19:53your chair or listening to this podcast later, you're conscious in that moment, you have
- 19:58those experiences right then, but that's a separate question from what binds your experiences
- 20:04together across time?
- 20:06What makes your experience from a year ago or 10 years ago somehow be part of the same
- 20:10person that you are right now?
- 20:12Okay, so we got two questions.
- 20:15What makes you conscious at the moment and personal identity and how does this relate
- 20:18to whether you're a copy or not a copy?
- 20:21So you can go through it quite laboriously.
- 20:24You can go through, well, maybe it's having the same body.
- 20:26Well, that doesn't seem to work because we're made of different stuff over time.
- 20:29Or you can say, well, maybe it's about having the same memories or the same consciousness
- 20:33or the same personality.
- 20:36That I think is a better argument for what makes someone the same person over time.
- 20:41And indeed, if you look at all the different options available, I think the best answer
- 20:46to the question of personal identity or what makes someone the same person over time is
- 20:51that they're able to hold on to their memories, their personality, their goals and desires
- 20:57through the maintenance of the particular structures of their brain that encode those
- 21:01things.
- 21:03And if you accept that is what helps you survive over time, then it does have the weird implication
- 21:08that even if you change someone's brain into completely different format, if you switched
- 21:13it out from biological components to electronic components or you transferred it over into
- 21:20a computer, that as long as the memories, personality, all those things were still there,
- 21:26then that would indeed still be the same person in the same way that I'm the same person,
- 21:31even though I'm not made of the same stuff I was 10 years ago.
- 21:34Yeah.
- 21:35I wanted to answer with like, oh, of course it's the continuity of self, you know, obviously,
- 21:40but that's even murkier than, I suppose, personality.
- 21:44But personality does change, you know?
- 21:47Yeah, it does and it doesn't.
- 21:49So like people's personalities are actually quite stable across their lifespan.
- 21:52You can like ask people the same questions or how would you react in these scenarios
- 21:56at different points of their lifespan?
- 21:58And they're much more similar to themselves over time than they are to the answers that
- 22:02other people give.
- 22:03Like if you're an extroverted person now, you'll probably be an extroverted person in
- 22:0720 years from now.
- 22:08And if you're an anxious person now, you'll probably be an anxious person in 20 years
- 22:12from now.
- 22:14But I just wanted to note that what the self is and what consciousness is also aren't necessarily
- 22:19the same thing in that it's definitely not the case that we have an unbroken stream of
- 22:26consciousness over our lifespan, where we go to sleep at night and we're maybe unconscious
- 22:31for a time or we undergo anesthesia and we're almost certainly unconscious for a time.
- 22:36Or even more radically, there's an already existing procedure that's used today where
- 22:41we induce hypothermia in people.
- 22:43So this isn't the brain preservation stuff.
- 22:46This is what they use in surgeries all over the world today.
- 22:50Well what they'll do is they'll take a patient, they'll cool them down to like 18 degrees
- 22:54Celsius or so, their heart will stop, their brain activity will stop.
- 23:00They'll look for all intents and purposes like a corpse, but it gives surgeons an operating
- 23:04window where they can operate on the blood vessels around someone's heart or the delicate
- 23:10blood vessels in their brain that they wouldn't otherwise be able to operate on.
- 23:14And it gives them like 30 to 45 minutes to work before they can then warm the person
- 23:18back up again and they're restored to consciousness.
- 23:21And somebody definitely wasn't conscious during this period of time.
- 23:25They didn't have any brain activity or really anything that could sustain consciousness,
- 23:29but they definitely survived this, meaning the self can survive even periods where consciousness
- 23:34isn't there.
- 23:37If I forced you to risk a prediction on when we would be able to achieve all of this preservation,
- 23:43scanning, reviving, et cetera, what would you say?
- 23:48So there's a difference between my view and what I think the community of neuroscientists
- 23:53would say.
- 23:54So I'm slightly more optimistic.
- 23:57I look at extrapolating the history of computing performance and I think about, well, so a
- 24:03brain maybe has something like, well, we know it has about 86 billion neurons.
- 24:09We know it's got about a quadrillion connections.
- 24:11We have an idea that we could model those things with maybe like each neuron could be
- 24:16modeled as like 10,000 different compartments interacting with each other.
- 24:20And you can put these sort of numbers together and get a guess at like what amount of computing
- 24:25power would be required to create like a digital version of a brain.
- 24:30And then you can look at like how computing performance has been improving over the years
- 24:34and you see things like, I think we've had a hundred million increase in computing speed
- 24:39since the 1990s to today.
- 24:41And if you think there's a chance that that will continue to hold, that Moore's law will
- 24:44continue to hold, that would give you an estimate of maybe we could produce an equivalent digital
- 24:51version of a human brain sometime in the late 2040s or early 2050s.
- 24:57But that's assuming everything went right and it never does in science.
- 25:01So probably at some later time point than that, maybe towards the end of the century.
- 25:06But actually I did a survey of neuroscientists recently of like randomly selected neuroscientists
- 25:13asking them these sorts of questions, being like, when do you think the first whole brain
- 25:17emulation of a human would possibly be created?
- 25:21And the average response I got from people was about 21, 25, I think.
- 25:25So sometime early in the 22nd century.
- 25:29Now these are all sort of ballpark numbers.
- 25:30I wouldn't put too much stock in them.
- 25:32I wouldn't be putting big bets down on like, this is the precise year, but that's sort
- 25:36of the vague numbers people have in mind for when these things might become possible.
- 25:41I just got a terrible idea.
- 25:43What if this actually happens, but then people in the future decide, for example, that I
- 25:48was a total piece of shit or something and then they just upload me in some nightmarish
- 25:54scenario like the final level of the video game Doom, which is basically in hell or something.
- 26:00You know what I mean?
- 26:02Yeah.
- 26:03So there's plenty of sci-fi stories that sort of explore these hellish possibilities.
- 26:08And like, they're obviously impossible to completely dismiss the idea that that might
- 26:13be something that happens.
- 26:15Because if you're saying this technology is possible, then it enables all sorts of scenarios.
- 26:19But my response would be is it's very strange to imagine a world in which someone would
- 26:23go to the bother of preserving you, of maintaining your preserved body for all this time, of
- 26:28working out how to revive and upload you, of restoring you to consciousness with all
- 26:33the expense that it would take to do that, to then just decide to like, torture you.
- 26:38I think in almost all circumstances, if people don't care about you, they're just going
- 26:43to let your body rot or like, not do anything.
- 26:45And the default state would be just to leave people in preservation or let them decay.
- 26:51I think what's actually much more likely is the only circumstance under which anyone is
- 26:55getting revived is if our descendants look at the world in which they live in and they
- 27:00see that that world is a better world than the world that we live in today, that we've
- 27:05solved climate change, we haven't destroyed ourselves with nuclear war, we've solved
- 27:10poverty issues, we provided wealth and prosperity to everyone.
- 27:15And they think, you know what, this is actually a pretty good world to live in.
- 27:19Like, maybe it would be a fun challenge to try and revive our ancestors and let them
- 27:23share this world with us.
- 27:24I mean, that's why I called the book The Future Loves You, because this is the sort of thing
- 27:29I think we should be working towards.
- 27:31And I think it's the positive vision of like, the kind of future we would like to live in
- 27:36is one that would be good for our descendants and then hopefully also good for us.
- 27:40Because in the same way, like, there's plenty of terrible things that exist at the moment,
- 27:44whether that's climate change, conflicts, inequality.
- 27:48But if you take a bit of a historical perspective, and you look back at the fact that like, 200
- 27:53years ago, one in two children died before they were 15.
- 27:56Most people lived in extreme poverty.
- 27:59There was considerably more violence than there is today.
- 28:03Women were oppressed, we still had slavery.
- 28:06Like, it's not that the world doesn't have problems, but it's getting better.
- 28:10And I hope that it will continue to get better in that way.
- 28:15So sort of like the Star Trek scenario, where we overcome these issues.
- 28:19But I don't know, I'm just imagining, since we're still very tribal, that in the future,
- 28:25if the conservatives have this technology, they're just going to revive the conservatives
- 28:30or vice versa, you know, this sort of scenario.
- 28:33Let's just revive the people that look like us or think like us.
- 28:36Well, there's all sorts of scenarios you can imagine.
- 28:38I mean, I think the default state, so we can imagine, I mean, I think there's a reasonable
- 28:43chance, unfortunately, that like the world does get destroyed or ends up impoverished
- 28:48or we don't end up producing a flourishing future.
- 28:50And if that scenario comes to pass, then none of what I'm talking about is going to work.
- 28:54So already we're assuming, you know, at least some groups of people have enough wealth and
- 28:59prosperity to be able to create the sorts of technologies I'm talking about.
- 29:04Then in that scenario, there's the question of like, well, how expensive will it be?
- 29:07Who will it be distributed to?
- 29:10Will it be distributed to everyone?
- 29:12Even if it is to everyone with what time costs, like who will get it first, those sorts of
- 29:16things.
- 29:18What I imagine, though, is like you can look around at medical technology we have today
- 29:22to give you maybe some hint of how it will go.
- 29:25Where certainly there's things that are very expensive and very unequally distributed,
- 29:31things like very expensive cancer therapies that only rich people in Western countries
- 29:36have any hope of getting access to.
- 29:38And that's tragic that more people can't use these who need them.
- 29:42But the general trend with all these medical technologies is we mentioned insulin before
- 29:48at the start of this chat.
- 29:50So Elizabeth, one of the first people to get insulin, she only really managed to get insulin
- 29:54because her dad, I think, was the former Supreme Court Justice, maybe a former vice president
- 30:01of the United States.
- 30:02So she was really on the short list for getting it.
- 30:04Yeah.
- 30:05So in 1919, that's 1921, sorry, that's what you needed.
- 30:09But today, a century later, basically everyone with diabetes has access to insulin.
- 30:14And in most places in the world, it's quite cheap and affordable and readily accessible.
- 30:19And that's mostly what we see for all medical technologies, where they start off being restricted
- 30:23to particularly well-off groups, but then they become easier and easier to access and
- 30:28more broadly distributed.
- 30:29And that's kind of what I guess would happen with this sort of revival technology as well,
- 30:33where maybe initially it's only used for those who have connections and money, but hopefully
- 30:38would become accessible to everyone over time.
- 30:42So suppose the future goes your way and we start doing this preservation en masse in
- 30:48the hundreds of millions.
- 30:49Where would the future humanity put all of these confused ancestors?
- 30:54Yeah.
- 30:55Well, there's the question of what do we do with people we preserve today?
- 30:59And what do we do with people once we revive them in the future?
- 31:03And so the first thing I would say is it seems like a lot of people, I think it's like, I'm
- 31:07going to get the exact number wrong, like 70 million people or so die every year at
- 31:12the moment, which is quite a lot of people, but people actually aren't that big.
- 31:17And we could fairly easily warehouse that number of people per year in an ongoing effort.
- 31:22It would cost a reasonable amount of money to do so, but an amount of money that's a
- 31:27few percentage of preexisting healthcare budgets typically.
- 31:33In fact, we talk about a lack of housing and a lack of land, but I think it's only something
- 31:37like 1% of all of Earth's surface, like landmass is currently built up on.
- 31:43So there is space for this sort of stuff.
- 31:45And you don't need prime real estate for warehousing bodies that are just preserved for a long
- 31:49period of time.
- 31:50But then there's the question of like, yeah, what do you do with people once you revive
- 31:54them?
- 31:55And then it really depends on the technology you have in mind.
- 31:59So if you live in a world where there is too many people, not enough space, not enough
- 32:04money, they're probably just going to not revive people.
- 32:08They'll leave them in the warehouses.
- 32:10It's only a world in which either we've worked out how to produce enough space here on Earth
- 32:14or space travel has gotten cheap enough that there's plenty of land up in the stars these
- 32:20days or where we've worked out how to do uploading and people can live in digital formats, taking
- 32:26up very little space, that I think anyone's going to start reviving people.
- 32:31Because the great thing about preservation is if our descendants don't have the resources
- 32:35to do it at the time, they can just leave people preserved until they do.
- 32:40Speaking of confused ancestors, here's my last gripe with the idea.
- 32:44Technological progress, like we talked about, seems to have gone light speed ever since
- 32:48the scientific revolution happened.
- 32:51And if anything, it's only speeding up as we go along, which means that 250 years from
- 32:56now, let's say, the world would be unrecognizable to us living here in 2024.
- 33:01Don't you think someone who's revived a quarter of millennia from now would basically just
- 33:06immediately become either severely depressed or maybe even insane due to shock and this
- 33:14insanely intense feeling of alienation?
- 33:17I have no doubt that the future, no matter what happens, will be extremely weird.
- 33:22So I agree with you on that one.
- 33:24Again, to pull up historical analogies in the same way that if we took someone from
- 33:28the 1800s who was, I don't know, a peasant farmer into today's world of supermarkets
- 33:34and aircraft and TikTok, they'd be like, what is going on?
- 33:38They'd be so confused.
- 33:41But that being said, I think if they were given supports to adapt to the language, to
- 33:45work out what was happening with technology, then they may well live, despite a period
- 33:51of confusion, a still satisfying life once they started to adapt.
- 33:55And we can see sort of analogous circumstances even today when occasionally there are people
- 34:00who've come from war-torn, developing, impoverished countries into rich, developed, first world
- 34:06countries.
- 34:08And when these people are given language classes, when they're given technology classes, when
- 34:12they're provided some sort of social community integration, typically they do describe having
- 34:18very high life satisfaction, particularly if they're able to take their friends and
- 34:23family and escape with other refugees with them.
- 34:26So I imagine in the scenario I'm talking about, we would all be as temporal refugees, we'd
- 34:31be arriving very confused into this future world.
- 34:35But again, my hope, and this is optimistic, but I think not entirely unrealistic, is that
- 34:41if our descendants bothered to revive us, they'd probably bother to help us integrate
- 34:45as well.
- 34:46Okay, I want to switch it up and just ask you, what do you think personally would be
- 34:51a good number of years to have, like just in general as an idea?
- 34:56Should we put a cap on it?
- 34:57Are we talking 150, 200, 1,000 years?
- 35:01Or just basically an indefinite life if no accidents happen or something?
- 35:04You could basically end whenever you wanted to.
- 35:07Yeah, I mean, the shorter answer is I think it should always be up to the individual.
- 35:12Like choices of health and lifespan should as much as possible be for individual people
- 35:17to decide.
- 35:18And if they want to live 150 years and no longer, fine.
- 35:21If they want to live 80 years and no longer, that should be up to them.
- 35:25But it's really a matter of giving people choices.
- 35:27Now, it might seem to people who are in their 20s and 30s and 40s that when they get to
- 35:33their 80s, they'll be like, well, I've done everything I set out to do, and I'm finished
- 35:38with life.
- 35:39But if you actually go and you survey those who are terminally ill, you go into hospices,
- 35:45you find people who are sadly dying of cancer, and you ask them like, what is your will to
- 35:51live?
- 35:52What you will see is that I think something like 70% of them in surveys that have been
- 35:56done still describe having a very strong will to live.
- 36:00And I think that's because for most people, whether they're 80 or probably even 100 or
- 36:05120, if you give them the option of another day in the sun with their relatives and some
- 36:11music and some ice cream or whatever else they enjoy, or if you give them more time
- 36:16to pursue their goals and their passions, people would generally like to live longer
- 36:21lives than we currently do.
- 36:23And like you can compare to some other animals where there are tortoises and whales that
- 36:28live for something like 200 and 250 years, and that seems like a better amount of time.
- 36:34Or you can look at darker versions where our ancestors lived something like 40 to 60 years.
- 36:39And that certainly seems like too little time, I think, to most people today.
- 36:44But the short answer is, yeah, I think people should just be able to choose for themselves.
- 36:48Well, speaking of years, why are we hardwired to only live about 75 to 80 years?
- 36:54Seems quite random.
- 36:55Although I guess any number would seem quite random, to be honest.
- 36:59But you mentioned whales.
- 37:00For example, I just read that they recently found a Greenland shark who was a 400 years
- 37:06old, 392 years old.
- 37:09Hardly fair, isn't it?
- 37:10Yeah.
- 37:11I mean, it's sort of it's a question we don't think about very much.
- 37:14We'd only just think, you know, humans live for 80 years, dogs live for, I'm going to
- 37:18get this wrong, I'm not a dog owner.
- 37:19Is it like seven to 10 years or something?
- 37:21It depends on the breed, but it's up to 15.
- 37:24It sucks.
- 37:25Yeah.
- 37:26Yeah.
- 37:27It's like one to two years, and then there's these like whales and sharks swimming around
- 37:31for centuries.
- 37:32Like what gives?
- 37:33How come we don't get to live that long?
- 37:35Essentially what it comes down to is an evolutionary trade-off between how quickly animals of a
- 37:42species can start reproducing and how likely they are to be killed by their environment.
- 37:48And it has to be this trade-off because actually, what would be evolutionarily optimal would
- 37:54be an animal that had really short reproductive cycles that bred all the time and was also
- 37:59immortal.
- 38:00It never died.
- 38:01Like that would be a perfect organism.
- 38:03It would just like continue breeding, continue breeding, continue breeding.
- 38:07But you can't do that.
- 38:08There's no way evolutionarily to design that.
- 38:10So what ends up happening instead is a trade-off between making something start breeding quickly
- 38:17and not really caring about how long it's built to last or building something to last
- 38:22a really long time, but making some sacrifices on how long it takes to start breeding.
- 38:28And this essentially comes down at a genetic level to choices that are made with individual
- 38:34genes and individual variants of genes that affect a whole bunch of different things.
- 38:39And you have to calibrate them.
- 38:41I say you, but evolution calibrates them either a bit more towards living longer or a bit
- 38:46more towards shorter reproduction.
- 38:49And the thing that really applies the pressure is how likely that kind of animal is to be
- 38:53killed by its environment.
- 38:55So for example, if you're a little mouse, you could build a mouse that didn't age and
- 39:00that had slower reproduction, but something's going to step on it or a cat's going to kill
- 39:05it or a snake's going to kill it in a pretty short period of time.
- 39:09So there's not really any reason to build a mouse that could theoretically live to 50
- 39:13years if it's just going to die from external causes within a few months anyway.
- 39:20But on the other side, if you're a giant whale, until humans invented harpoons, basically
- 39:25nothing could kill you.
- 39:27So it made sense to build it so that it didn't get cancer, it didn't get heart disease,
- 39:31it just lasted a really long time.
- 39:33And so it doesn't matter if it doesn't start breeding until it gets to 13 or 15 or something
- 39:38if it's going to live 200 years afterwards anyway.
- 39:41So that's where it comes from.
- 39:43So with humans, we live 80 years, which is pretty good for most species, basically because
- 39:48we are pretty good at sticking around for a while and not being killed.
- 39:52But we still, compared to whales, have some significant sources of things that kill us.
- 39:57And the two things historically that did that, one was infections, getting cuts or pneumonia
- 40:02or any of those sorts of things.
- 40:04And the other thing sadly was other humans, where I think historically we had something
- 40:08like a 15 or 10% rate of homicide or being killed by other people.
- 40:15So yeah, that's why we live 80 years.
- 40:17Yeah, it's fascinating how it's all about perspective.
- 40:21Like you said, when I was 19, I was like, 80 years, what am I going to do with all this
- 40:25time?
- 40:26You know, Jesus Christ.
- 40:27And now, and I'm almost 40.
- 40:29I'm like, what the hell?
- 40:31Only 80 years?
- 40:32That sucks.
- 40:33A common experience, I think, for people.
- 40:36And when you were explaining how it works, it's so brutally functional in a way.
- 40:43So in a nutshell, the more dangerous there are out there trying to kill us, the shorter
- 40:47our reproductive age, the faster we die.
- 40:50Is that it?
- 40:51Yeah.
- 40:52Yeah, pretty much.
- 40:53I mean, like nature and biology is like beautiful and fascinating, but it is also extremely
- 40:59cruel.
- 41:00Like evolution doesn't care about anything except inclusive fitness, reproductive ability.
- 41:05And it'll sacrifice years of people's lives or health or anything if it will slightly
- 41:11improve fitness.
- 41:13And it's pretty horrible.
- 41:16I watched an interview you did for another podcast discussing your book.
- 41:19And most of the comments underneath basically kind of coalesced around the same idea.
- 41:24And there was people saying, you know, by the love of God, I don't want to go to work
- 41:28for 200 years more.
- 41:31And I just want to live a better, not a longer life.
- 41:34But I guess those two aren't mutually exclusive necessarily.
- 41:38However, there seems to be the idea that people want to live in a much better world first
- 41:44before we begin talking about living drastically longer lives.
- 41:48Yeah, it seems a little odd depending on how you ask the question.
- 41:52You get different answers from people.
- 41:54And I even am not entirely sure how to square this all together yet.
- 41:57So I have heard comments like that.
- 42:00But what's a bit odd is if you also ask people, how satisfied are you with your life?
- 42:05Or is your life worth living?
- 42:08Most people, at least in developed countries, actually say, yes, my life is worth living.
- 42:13I think out of a score of one to 10, where one is not good at all and 10 is the best,
- 42:19people in Europe and the US and Australia typically give something like a seven out
- 42:23of 10.
- 42:24That doesn't mean everyone.
- 42:26Some people sadly don't have great lives for all sorts of psychological, medical, social
- 42:34reasons.
- 42:35But the typical person does say and does think that they have a good life.
- 42:40So even if all we could offer people was a continuation of their current existence, but
- 42:45for longer, I think many people would quite like to take that up.
- 42:50But that being said, also, I agree with them when they say, you know, we should be working
- 42:54on producing a better world and focusing on that.
- 42:58I just don't think they're exclusive.
- 42:59In the same way that we should be trying to ensure that wealth is distributed to more
- 43:04and more people instead of captured by an elite, in the same way we should be trying
- 43:08to cure diseases that are still afflicting people, we should be doing all of those things
- 43:13at the same time as improving living standards and improving working standards for people.
- 43:18I don't think you have to choose one or the other.
- 43:20Since I can only relate to these things in like trashy pop culture terms, have you seen
- 43:25the movie Elysium?
- 43:26It's a sci-fi starring Matt Damon, where the oligarchs, the elites live on like a private
- 43:32moon where they have the technology to live endless and endlessly healthy lives while the
- 43:39rest of the folks live in squalor in these sort of giant favelas on Earth.
- 43:45This also seems like a pretty plausible scenario, no?
- 43:49I think if we had a world in which we developed some sort of anti-aging medicine, but it costs
- 43:54like $50 million for it to work, that would be really like dire.
- 44:01I still think it would be good to have something that we could work on making cheaper, but
- 44:05we would be dealing with these really difficult ethical questions of like, how can we ensure
- 44:09access?
- 44:10Is this equitable and fair?
- 44:12I guess, unfortunately for billionaires, but fortunately for everyone, I don't think that's
- 44:17going to happen anytime soon.
- 44:20My proposal is much weirder, where I'm saying I don't have a way to keep only billionaires
- 44:25alive for centuries.
- 44:27I think we have a preservation technique that has an enforced period of stasis, but which
- 44:32could actually be done fairly cheaply.
- 44:35My estimate is something like $10,000 per procedure to preserve someone and maybe a
- 44:41few hundred to $1,000 a year in storage costs if these procedures were provided at scale,
- 44:47which is well within the sorts of surgical medical costs that are provided to people
- 44:51generally, again, in Western developed countries.
- 44:57It's not the case, I think, that in the near term, we're going to be seeing only these
- 45:00sorts of things being available only to the super rich and everyone else just left to
- 45:04die.
- 45:05I think the main constraints are do people actually want to take up these sorts of preservation
- 45:09technologies, not will they be able to afford them.
- 45:13That's separate to the revival.
- 45:14I think revival might be quite expensive at some point in the future and more like other
- 45:18things where it starts super expensive and then gets cheaper.
- 45:21But again, the great thing is as long as someone's preserved, they can wait until it becomes
- 45:25cheaper.
- 45:26Yeah.
- 45:27Also, what's cool about this idea is that if we do become a better society or better
- 45:32humans in the future, they could choose individually who to revive and who not to revive.
- 45:37They would basically say, oh, this person was really cool.
- 45:41They weren't just hoarding wealth.
- 45:44Let's revive this person.
- 45:45Maybe they're there.
- 45:47We don't have any more use of these.
- 45:49This is an idea I speculate on in the book where I hope that future generations will
- 45:54be better people than we are today.
- 45:56In the same way that we don't have slaves, we're nicer to women.
- 46:00We generally, despite our flaws, I think nicer to animals in the world than we were in times
- 46:08before.
- 46:09There's still a lot of improvements that we could do.
- 46:12I hope that people a few centuries from now will look back on us and be like, yeah, they
- 46:16did some pretty hard stuff, but we're graceful and kind and generous and we'll revive them
- 46:21regardless, particularly if we've done a good job of improving things.
- 46:25But I definitely think it's the case that if you're the sort of person who contributed
- 46:30to making the world a better place in the future, if you're one of the people who did
- 46:34nice things, solved problems, otherwise overcome the difficulties and challenges of our time
- 46:41to contribute to advancements, maybe you get bumped up the revival list or something.
- 46:47Who knows?
- 46:48But this is very speculation.
- 46:51All right.
- 46:52I want to talk about the more quote unquote philosophical implications of potentially
- 46:57living forever.
- 46:58What do you think would happen to our very nature if we did end up being basically immortal?
- 47:07Would we still be humans or would we be something else?
- 47:11I mean, it again depends on what you define as core to being human.
- 47:15If you mean that to be human is to have the particular genetic makeup that makes up a
- 47:21human cell and differentiates a human cell from a chimpanzee cell from a mouse cell,
- 47:27then I guess if we start messing around with the fundamental building blocks of what we've
- 47:30made of, arguably we wouldn't be human anymore.
- 47:34But I don't think that's what most people think or really care about when it comes to
- 47:37being human in the same way that I don't think somebody thinks they're a different person
- 47:41if they get a prosthetic implant, whether that's false teeth or an artificial heart
- 47:45or any sort of artificial device.
- 47:49I think what most people think is core to being human is having love for one's friends
- 47:54and family, experiencing the world in the particular way they do or having particular
- 47:59tastes or musical preferences or professional goals, those sorts of psychological things.
- 48:06And I think that if revival is successful, the only way it could be successful and it
- 48:11could really bring a person back would be if it held on to those things which are core
- 48:15to making people who they are.
- 48:18And in that sense, I'd say that people would still be human or at least this wouldn't work
- 48:23unless it kept that part of our humanity.
- 48:26I guess I was maybe asking about a sort of existential motivation that is derived from
- 48:32the awareness that the number of years on this earth is limited to us.
- 48:37So we better do something useful or meaningful while we're here.
- 48:41With this removed, would we still care about anything?
- 48:45I don't think most people really go about their lives and are motivated to action because
- 48:50they're worried that in some time period from now, they're going to die.
- 48:55When people are going to a party, I don't think they're like, well, I've only got X
- 48:58many parties left before I end, or when they go for a promotion, I think that they're more
- 49:03motivated by proximate goals of wanting to achieve things in the meantime or enjoy a
- 49:08particular day or a holiday in a shorter period of time.
- 49:11That's not to say people don't have goals that take years or decades to complete.
- 49:15But again, I think it's the goal itself that mostly is what's motivating people rather
- 49:20than the knowledge of there being a deadline at the end.
- 49:23And I think this becomes a bit obvious when you think about the fact that if we knew that
- 49:26we lived for 200 or 300 years, I don't think that would put people off from doing things
- 49:32at the moment.
- 49:34Maybe on the margin, it might make them procrastinate a little bit more.
- 49:38But I think for the most part, people already procrastinate today knowing that their lives
- 49:43are short.
- 49:44And a lot of people get a lot of stuff done with no regard for the fact that it's because
- 49:49they're going to die.
- 49:51So I suppose you don't believe in this Freudian death drive that basically deep down we all
- 49:57want to die at some point.
- 49:59I imagine especially if we indeed have lived healthy, full and meaningful lives.
- 50:05No, it both doesn't make sense to me on a personal emotional level.
- 50:10I don't see the argument for it at a philosophical level.
- 50:12And it would be a very weird thing to evolutionarily program into an animal to have it be okay
- 50:18with or even strive for its own eventual death.
- 50:22What do you think would happen to relationships if you were married to somebody or friendships
- 50:29even that you're like, oh, damn, I have to spend the next 500 years with this person
- 50:34now?
- 50:35It would change pretty much everything when we talk about these timescales.
- 50:39I think it would get...
- 50:41Sorry, I keep interrupting.
- 50:44I think it would get complicated, but probably better in a lot of ways despite being weirder.
- 50:50I mean, I think about people I've been friends with since I was a child.
- 50:54And I used to have maybe when I was at school, much like stronger and more frequent interactions
- 50:59with.
- 51:00But nowadays, I still have very rich relationships with these people.
- 51:03Even if it's one of my best friends who I only see every couple of months or every six
- 51:06months these days.
- 51:08What I imagine is you would start to develop many, many more of these sorts of things where
- 51:12there'd be people who'd be really intensely part of your life for a period of time.
- 51:16And then you might drift apart for a while, but you'd still hold on to these strong connections
- 51:20to people.
- 51:22That would be my guess in one sense.
- 51:24And also, there's already relationships today, whether it's people who have family members,
- 51:31whether that's your brother or sister or a child or a partner, where it doesn't really
- 51:35seem like over the years and decades, people get sick of each other or want to stop spending
- 51:40time with each other.
- 51:41I haven't really come across a parent or a grandparent.
- 51:44Well, I shouldn't say haven't.
- 51:46But most parents or grandparents are still quite happy to see their kids and grandkids,
- 51:51even if it's for the hundredth, thousandth, ten thousandth time.
- 51:55Now there's more complication, I admit, when it comes to romantic relationships.
- 52:00Many couples are...
- 52:01I suppose the argument is out of the question.
- 52:02Well, I think that's up for each couple to decide.
- 52:05It works well for some people.
- 52:07Perhaps it would become more strange for others.
- 52:09And that would be complicated, but I think it's a much nicer problem to have than the
- 52:14one of it being till death do us part, which is what we have at the moment.
- 52:18Better they have to talk about it again in 50 years or 100 years from now.
- 52:23Do you think there's some sort of like a hard drive that we have a limit when our brains
- 52:28are concerned of how much information we can retain?
- 52:31If we do end up living for 500 years, would you be able to remember things?
- 52:38Or like basically process new information?
- 52:41Or would you just be like oversaturated and overwhelmed by everything that's happening
- 52:46all the time?
- 52:48This is a fascinating question.
- 52:49And I think, unfortunately, one that we really don't have a clear answer to as of yet.
- 52:53But I'll talk through how one thinks about it.
- 52:56So we know, as I mentioned before, a brain has something like 86 billion neurons and
- 53:01a quadrillion connections.
- 53:03So a huge number of connections, but still a finite number of connections.
- 53:09It's not expandable at this point in time.
- 53:12So there's presumably only so much you can pack into it.
- 53:14But what we don't know is like, what is the limit of what can be packed into it?
- 53:19Because it could well be the case that a lot more that can be packed into a human brain
- 53:23than ever actually fits into it during a typical human lifespan.
- 53:27Because it's not the case that people die because their brains are oversaturated and
- 53:31their memories are falling out in the end.
- 53:34Typically people get cancer or heart disease and die before those limits get reached, whatever
- 53:39they are.
- 53:40Even in things like dementia, that's not being caused by people's brains filling up.
- 53:44That's called, we don't really know what the cause is, but we know that it's associated
- 53:48with synapses, brain connections being destroyed, and then the neurons themselves actually dying.
- 53:54Not that like there's too many connections forming and somehow it stops functioning.
- 53:59So the question is like, well, actually, maybe you could pack 150 years, 200 years, 500 years
- 54:06worth of memory in there.
- 54:07We're not sure.
- 54:08Certainly, there's other precedents of human brains being able to do amazing things that
- 54:13you wouldn't have been able to predict ahead of time.
- 54:15So some obvious examples being, our ancestors would only have met a few hundred people in
- 54:22their lifetime back if you live like 500,000 years ago.
- 54:26So they wouldn't have had to recognize that many faces, but it turns out that like human
- 54:30stay can end up recognizing thousands and thousands and thousands of faces.
- 54:34So a much greater capacity was built in than what was actually needed.
- 54:39And there's other cool things like we're able to read, even though reading is only something
- 54:42that's existed for a few thousand years.
- 54:44Essentially, again, because of like spare capacity in our brains compared to what was
- 54:50evolutionarily designed for.
- 54:52So my guess is it would be you could store a lot more memories than typically fits into
- 54:57a human lifespan, even if maybe it starts to become a problem at some point, and then
- 55:02we'd have to work on brain implants, other solutions to that problem once we got there.
- 55:08So this sort of neuroplasticity could be potentially endless.
- 55:12But I had a high school reunion recently.
- 55:15And while I did remember the faces, I can't remember like the last names, even though
- 55:20it was like, you know, 19 years ago.
- 55:22So I don't know, I'm a little bit skeptical.
- 55:25Maybe that's just my core cognitive performance.
- 55:28No, no, no, we do obviously forget things.
- 55:31We do tend to forget things that are less important, less salient to us.
- 55:35We discard mostly information that is less meaningful, and we hold on to the things that
- 55:39are really core to us.
- 55:41So it's not that there's nothing lost.
- 55:43And it would be great if we had means of preventing those sorts of losses.
- 55:47My point is just that like we can pack a lifetime of experiences in.
- 55:52Elderly people outside of cases of dementia typically are able to recall a truly staggering
- 55:57number of memories and episodes from their lives and amounts of material that they've
- 56:01recalled and remembered.
- 56:04And my suspicion is, if we were able to get around these other health issues, even typical
- 56:10human brains could store a whole heap more than they are currently able ever get to.
- 56:16At the end, I just had another horrific kind of thought.
- 56:21I personally don't believe in it, but I hosted Dr. Bruce Grayson, who's studying NDEs a while
- 56:27back.
- 56:28Near-death experiences?
- 56:29Exactly, yes.
- 56:31And he sort of convinced that there is something after death.
- 56:35It would kind of be tragic if we did end up living forever, end up being almost immortal,
- 56:43and then denying ourselves the chance to experience the afterlife if it does exist and it's just
- 56:49like an amazing endless party or something.
- 56:52Would be ironic in a dark sort of sense.
- 56:55Absolutely, that would be tragic.
- 56:57I just think the evidence for an afterlife is not particularly strong insofar as people
- 57:03have not proposed clear mechanisms through which something like that could really work.
- 57:10I mean, if it is the case that, for example, humans have souls and when a person dies,
- 57:15the soul leaves the body and goes to the afterlife, I guess what I would say is I don't think
- 57:19the preservation techniques I'm proposing would be able to bind someone's soul.
- 57:24If it's an immaterial soul, then the preservative chemicals presumably aren't going to hold
- 57:28onto it.
- 57:29So you'd still get to go to the afterlife.
- 57:31But from what I can see is arguments involving souls or sort of spiritual dualistic accounts
- 57:42of what it is that gives us our consciousness, makes us who we are, don't have a lot of explanatory
- 57:48power at being able to say why it is that someone's memories or personality changes
- 57:52when they get a head injury or why it is that we lose consciousness when we undergo anesthesia
- 57:58or are hypothermic.
- 58:00These things seem much better explained by suggesting that what is core to being a person
- 58:05is having particular kinds of brain activity in the particular structures of our brain.
- 58:10And the flip side of that is if that activity stops permanently or those brain structures
- 58:15are destroyed, then there's pretty strong evidence to think that the person's just gone
- 58:19forever from that point onwards.
- 58:21Yeah.
- 58:22I did tell them during our interview that I did undergo anesthesia and there was just
- 58:26like an absence of everything.
- 58:28So I was like, okay, that's it when you die.
- 58:30That's probably it.
- 58:31Yeah.
- 58:32But his argument was...
- 58:33That's exactly what I think happens.
- 58:34Yeah.
- 58:35But his argument was more in the line of like our brain being a receiver of some sorts.
- 58:39So if you damage the receiver, of course, you're not going to get a clear picture.
- 58:45Yeah.
- 58:46I mean, so I understand what I'm proposing sounds super weird and people are probably
- 58:50really skeptical of what I'm saying.
- 58:52So I encourage skepticism.
- 58:55And I would say that if you have really weird claims like my brain preservation ones or
- 58:59this guy's near-death experiences due to spiritual connections to souls or something, I don't
- 59:05want to necessarily just like completely dismiss things out of hand just because they're weird.
- 59:09But what you have to do is you have to say like, this is how my argument could be proven
- 59:12or disproven.
- 59:13Here's an experiment that you could run.
- 59:15And I know that because people have tried running experiments with these near-death
- 59:19experiences that there doesn't seem to be much experimental evidence to back them up.
- 59:23I think the most famous one is there's this proposal that like people would ascend out
- 59:28of their bodies during near-death experiments.
- 59:30And then they would put something, some object somewhere.
- 59:32Yeah.
- 59:33And so they put objects up, they ask people if they could like report the objects that
- 59:36they saw and nobody's been able to show that that happens.
- 59:39So that's sort of experimental falsification of the claims to a degree.
- 59:44Ariel, thank you so much.
- 59:46I can recommend your book enough.
- 59:49Who knows?
- 59:50Maybe I'll see you in the year 225 where we're both like revived in our sexy new bodies or
- 59:55minds or whatever.
- 59:56Yeah.
- 59:57I'd love to do this interview again then.
- 1:00:00I'd love to see you and all your listeners then.
- 1:00:02Thank you so much.
- 1:00:04Last thing, do you have social media where people can see what you're up to these days?
- 1:00:08Yeah.
- 1:00:09I've got Twitter, which is ariel-underscorezj and I've got Blue Sky, which is arielzj and
- 1:00:17I've got a whole bunch of like YouTube interviews and print interviews.
- 1:00:21If you go to my website, arielzj.com, everything's linked from there.
- 1:00:25Awesome.
- 1:00:26And where can people get your book, find bookstores everywhere?
- 1:00:29Amazon, bookstores, anywhere.
- 1:00:31Just have a Google and you'll be able to find it.
- 1:00:34Awesome.
- 1:00:35Thanks again.
- 1:00:36This was an absolute blast.
- 1:00:37Thanks.
- 1:00:38It's been a pleasure to be here.
- 1:00:39Please subscribe to the podcast on YouTube.
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- 1:01:29Thank you so much.