1132-Astrocytic Sodium Homeostasis in Mouse Brain
This research article details the discovery of significant cellular and subcellular sodium heterogeneity within mouse brain astrocytes. Using advanced multi-photon fluorescence lifetime imaging (MP-FLIM), the authors demonstrate that internal sodium levels are not uniform, as previously believed, but vary between the cell body and its processes. The data reveals a bimodal distribution of sodium concentrations, suggesting that astrocytes are organized into functionally distinct subgroups rather than a single homogenous population. These variations appear to be driven by the differential…
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