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Latest / Decera Clinical Education Oncology Podcast

The Latest Evidence on Targeting B7-H3 in Small Cell Lung Cancer

In this episode, hear Lauren Byers, MD and Christine Hann, MD share their insights on the latest data regarding new therapies targeting B7-H3 in small cell lung cancer including:

Rationale for targeting B7-H3

Overview of the structure of antibody-drug conjugates (ADCs)

Results from the phase I/II IDeate-PanTumor01 trial of ifinatamab deruxtecan (I-DXd) in ES-SCLC

Data from the phase II IDeate-Lung02 trial of 2 different doses of I-DXd in patients with previously treated ES-SCLC

An overview of the ongoing phase III trials IDeate-Lung02 and IDeate-Lung03 of I-DXd in SCLC

Early phase evidence on…

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