a16z Podcast: On the Genomics of Disease, From Science to Business
Once we sequenced the human genome, we'd know the cause of -- and therefore be able to help cure -- all diseases... Or so we thought. Turns out, 20,000 genes (and counting) didn't really explain why disease occurred. Sure, some could be explained by mutations in a single genome, but most, like cancer, are too damn complex. And while the focused, singular approach to understanding disease did yield some useful therapeutics, it's now reached its limits. It hasn't helped much on the diagnostics (and early detection) front, either.
That's where a systems approach to bio comes in, drawing on…
The skinny
The skinny isn't ready yet — notes appear once the transcript is processed.