1467-Antibiotic-Induced Horizontal Protein Transfer
This research article identifies a novel method of horizontal protein transfer where bacteria exchange functional proteins via membrane vesicles to survive antibiotic stress. Researchers developed a Cre-loxP genetic system to track these events, discovering that antibiotics trigger a population to split into vesicle-producing donors and protein-receiving recipients. This exchange is driven by the Psp membrane stress response, which regulates both the secretion of these protein-filled particles and their subsequent uptake. The study highlights that recipient cells often exist in a state of…
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