Latest / The Sirona Health Podcast: PMDD, Hormones & Mental Health

PMDD: It's Not Your Hormone Levels, It's Your Brain
If your hormone tests keep coming back "normal" but you still feel awful — this episode explains why. Dr Georgina Standen breaks down the real science behind PMS and PMDD: it's not about how much oestrogen or progesterone you have, it's about how your brain responds to it.
In this episode:
Why women with PMS and PMDD usually have completely normal hormone levels — and why that's not a dead end
The lab research showing PMDD cells respond differently to the same hormone exposure, right down to gene expression
Why SSRIs can work within days for PMDD, when standard depression treatment takes…
The skinny
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