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Lessons - How Your Gut Health Determines Your Life Span | Dr. Steven Gundry - Renowned Heart Surgeon · Success Story with Scott Clary

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  In this lessons episode, discover how your gut influences nearly every system in your body.
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  Learn why the microbiome is considered a second brain, learn how chronic inflammation in the gut
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  can lead to heart disease, dementia, and brain fog, and learn what ancient cultures teach us
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  about rebuilding a healthy gut to prevent modern disease.
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  Why for the longest time did we not try and explore this more?
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  I think one of the huge pieces of this was, for instance, I had the former head of the FDM,
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  my podcast a few years ago and we were in the same age and we were chuckling that back when
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  we were in medical school, we thought the gut was this hollow tube and we swallowed things and
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  magic happened and we absorbed things and then whatever we didn't need was pooped out the
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  rear end and that was about all we knew. And then we discovered that there were actually
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  more nerves, neurons in the gut that were surrounding the gut than there were in the spinal cord.
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  So the word second brain came about and then we began to realize that, oh my gosh,
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  we didn't know these bugs existed because the only way we could identify these bacteria was either
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  look at them under the microscope and they all look kind of similar or we try to grow them
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  and most of these bacteria wouldn't grow, we didn't have the techniques.
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  So with the human microbiome project, once the genetic code was cracked,
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  you could use computers to look at the genetic code of microbes and the genetic code of microbes
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  is different from every microbe and then look at stool and rather than trying to culture bacteria,
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  trying to look for bacteria, all you need to do is look for their genetic signature.
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  And when they did that, lo and behold, there's 10,000 different genetic signatures that we thought,
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  oh, maybe there's 100 or so. And there's a trillion, a hundred trillion of these guys living in us
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  and then it gets even better. Each of these different species have, you know, different subclasses
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  and geniuses and like just last week, there's a really cool bug that I write about.
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  That's a very important bacteria called acrimoncium, eucinophila,
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  mucous loving acrimoncium and it's really important and we'd get into that if you want to,
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  but it took researchers 10 years to actually grow this bug. You couldn't grow it and now it's
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  done, but now we know that there is a cousin of acrimoncium, not mucinophila, another guy,
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  who's probably even more important. And we didn't even know he existed because we didn't know
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  that little signature difference. So now everybody's excited, oh my gosh, and we got to grow this guy.
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  So the other thing is if you would ask me 30 years ago what I thought about leaky gut, I would
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  indulge it with pseudoscience, it was woo, and thanks to people like Dr. Lesio Fizzano is a
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  pediatric gastroenterologist now at Harvard who literally broke the code to find out, you know,
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  could you, does leaky gut exist? I guarantee you that exists. He proved it, we can prove it,
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  we can measure it. So all of this kind of pseudo stuff, how apocrates knew this? I don't know,
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  and that's what I'm trying to figure out, but the longer I do this and the more science we apply
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  to this, the more it's like son of a gun, you know, there is this brown life force energy that was,
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  it was these guys. Incredible. That's incredible. So then, so what does this dis, because obviously
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  second brain means that it's controlling and influencing almost every part of our body to a degree,
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  but what are the major things that it's disproving that we thought and held true before we had
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  this research? Okay, that's, that's an excellent question. I, for one, it was a heart surge in
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  their cardiologists who have thought the cholesterol theory of heart disease was a pretty good theory.
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  It turns out it's a horrible theory. Michael DeBakey, one of the fathers of heart surgery, said
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  cholesterol has nothing to do with heart disease. It's an innocent bystander. And you go, so inflammation
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  in the lining of the blood vessel is actually the cause of heart disease and cholesterol just
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  happens to be a spackling compound that tries to cover up what's going on on the blood vessel.
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  We could get back to Big Ed, but for the purpose of how he did it, because I've written about how he
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  did it, inflammation, all inflammation comes from the gut. People go, well, if I eat anti-inflammatory
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  foods, I'll stop inflammation. And since there are wildfires in California nearby me right now,
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  I can assure you that fighting inflammation with anti-inflammatory foods is like putting out a
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  forest fire with a garden hose. And we, we learn repeatedly, you can't do that. So you have to find
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  the source of the inflammation. And all disease begins in the gut and the inflammation is coming
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  from the fat. That the lining of our gut is, it's got a design flaw. Now that design flaw is,
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  the lining of our gut is about one to two tennis courts in surface area, insiders. And it,
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  it only has one cell thick. Everything you swallow is separated from the rest of you by only one cell.
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  Now those cells, this is one cell. Those cells are held together by a glue that's called a tight junction.
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  Are you old enough to have played Red Rover, Red Rover? Yeah.
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  The reason I have to ask now is it's illegal? Actually, play Red, yeah, schools ban it. Why?
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  You cannot play. It's too dangerous, of course. So these cells are bound together. They're locked
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  arm and are, you know, like Red Rover. And so everything you swallow is here. All the bacteria are here.
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  And there's only one cell between standing between everything you swallow all the bacteria and us.
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  Now on the other side of this wall, 80% of all your white blood cells
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  are there. Why? Why are they there? Because this is where trouble could come across.
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  Now trouble can come across. There's no question that trouble comes across. But it's usually a small
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  incursion and then the guys put out the incursion and that's the end of it. But what has been shown over
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  and over and over again now is that this incursion goes on every day, every night and that there is a
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  chronic incursion across the wall of the gut. And the immune system not only is doing battle
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  at the wall of the gut, but the immune system literally sends out warnings in the form of
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  hormones called cytokines that among other things go up to your other organs, go up to your brain.
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  It says, oh my gosh, we're under a massive attack. Take cover or prepare the defenses.
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  Or we have a set of immune cells in our brain that are called microglia that are kind of the
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  bodyguards of the neurons are that important. And when these bodyguards get alerted that mischief
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  is on the way up, they actually take action to try and protect the neurons and they do it in a bad
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  way. They actually make a neuron stop talking to other neurons to protect themselves.
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  That's where brain fog comes from. We now know that Parkinson's comes from the gut, dementia comes
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  from the gut, Alzheimer's comes from the gut and getting back to the original question,
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  heart disease comes from the gut. And better way of saying is death begins in the gut.
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  But the good news is all disease comes from the gut and thankfully all disease can be
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  reversed from the gut. So that would be that would be the question that everybody wants answered.
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  So what do you start to do to make sure that your gut, your microbiome is working properly so that
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  you don't have all these all these diseases? Well, nobody used to have these. One of the things
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  that's been fun looking at ancient cultures or the cultures that don't have these diseases
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  that believe it or not, there are cultures that have no heart disease just as an example.
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  There's a group of islanders in Papua New Guinea called the Catavans that
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  a Danish researcher Stefan Lindbergh spent his life studying these were the group of islanders
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  who smoked like fiends and they had no coronary arteries, no stroke, and no cancer.
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  And he spent his life trying to figure, well, how can that be?
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  And it turns out that they because of what they ate had a perfect microbiome had a perfectly
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  intact wall of their gut. And yeah, smoking is bad for you and people accuse me of telling people
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  that smoking's good for you. Well, it turns out that four of the five blue zones are heavy
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  smokers. So maybe we ought to be interested in why it wasn't killing them and might have been
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  helping them, but that's another subject. But these people were able to defend against the
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  bad parts of smoking by having an antioxidant rich diet among other things. So
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  and you look at these cultures that don't have what we have, one of the things that's remarkable
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  is that they have this really incredible tropical rainforest of gut microbiome.
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  And Hillary Clinton would say it takes a village, but we used to have this incredible tropical
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  rainforest. And it could handle anything that came down the pike and this tropical rainforest
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  was capable of making sure that nothing bad got to the wall of the gut. And if the wall of the
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  gut was damaged, that they made compounds that actually rapidly repaired the wall of the gut.
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  Now, as any of us know, our tropical rainforest is a desert wasteland. We have destroyed it in
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  lots of fascinating ways. Number one, antibiotics, broad spectrum antibiotics. I was actually
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  in medical school when broad spectrum antibiotics were introduced. And we just thought it was the
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  greatest advance in the history of mankind. Because before then, we had to try and figure out what
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  bacteria was causing. And we had to try and grow it. We had to test antibiotics against it.
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  And it was a time-consuming process. And you should be wrong. Then all of a sudden,
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  we had an AK-47 and sat on automatic and we could mow down every living bacteria,
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  known and unknown. But we had no idea that we were also killing off these guys that lived in our
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  gut because we didn't even realize they were there. And then we found out that you could make
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  animals grow faster and fatter if you gave them antibiotics. So almost all of our animals were
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  given antibiotics. And so, presto change, oh, that's one thing that happened. Then glyphosate came
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  along round up. And most people don't realize that Monsanto patented glyphosate as an anti-biotic,
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  not as a weed killer. Oops, that should make us worry. And speaking of the brain, it turns out
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  that glyphosate targets the bacteria that live in our gut that make the feel good hormones.
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  The anti-exaggerated hormones, things like serotonin and things like GABA. And we have to have the
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  bacteria actually make those hormones for us. We didn't know that. We thought neurons did that.
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  And now we've killed those guys off. So is it any wonder that we have this epidemic of anxiety
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  and depression that, you know, it's just unbelievable. Yes, we have things to be depressed about
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  and anxious about. But the epidemic is staggering. And it's just we've just killed off this incredible
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  part of us unwittingly, hopefully unwittingly. And building it back is part of this book. It can
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  be built back. The tricks are in the book to help you build it back. But uh, and that's part of the
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  start. Thanks for tuning in. If you found this valuable, don't forget to hit that subscribe button
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  so you never miss an episode. And if you want to dive deeper into this conversation,
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  check out the links in the description to watch the full episode. See you in the next one.