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Cancer Hijacks Nerves via BDNF | Science News
Scientists uncovered a sneaky tactic used by aggressive triple-negative breast cancer: tumors hijack immune cells called macrophages to deliver BDNF, a brain-growth protein repurposed to lure nerves into the tumor. This nerve infiltration fuels cancer growth and is linked to worse patient outcomes. But here’s the twist—when researchers blocked the BDNF signal in mice, tumors shrank and nerve invasion stopped. This could lead to new treatments that disrupt cancer’s communication with nerves, not just attack the cancer cells directly—and it might work beyond breast cancer too. Listen in…
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