Latest / Pediatrics Now: Cases Updates and Discussions for the Busy Pediatric Practitioner / Treating Teen Obesity: A National Leader in Bariatric Surgery on GLP‑1s vs. Surgery
Transcript
- 0:01I'm Holly Wehmint, and this is Pediatrics Now.
- 0:05Click on the link in this podcast for free credit that may include CME,
- 0:08MOC, or ethics credit, depending on your topic or podcast.
- 0:14I'm here today with Dr. Richard Peterson. He's the immediate past president
- 0:18of the American Society for Metabolic and Bariatric Surgery,
- 0:22Chief of Metabolic and Bariatric Surgery at UT Health San Antonio,
- 0:26Division Chief of General and Minimally Invasive Surgery, and Surgery Quality
- 0:31Director at University Hospital.
- 0:33He's helped shape national standards for bariatric surgery and obesity care
- 0:38and is a recognized leader in treating obesity in both adults and adolescents.
- 0:43Dr. Peterson, welcome to Pediatrics Now, and thank you for being here in the podcast studio.
- 0:48Holly, thank you so much for the opportunity. And I know it took us a little
- 0:51time to align our schedules, but today is the day, and it was meant to be this
- 0:56way, so I'm glad it worked. It's great to have you here.
- 0:59Dr. Peterson, let's start with the big picture. Many centers have reported declines
- 1:03in bariatric surgery volumes since GLP-1 medications became widely available.
- 1:10Given the national vantage point you have leading the field's largest professional
- 1:15society and having led that professional society, what are you seeing across the country?
- 1:20Are we witnessing a permanent shift or are surgery and medications finding complementary roles?
- 1:26Yeah, I think that is a great question. It's really the 10,000-foot view when
- 1:32you look at everything is, yeah, there's definitely been a decline in metabolic
- 1:36and bariatric surgery over the last two to three years.
- 1:40And even we took a little bit of a hit during COVID.
- 1:45So you might remember most elective surgeries were put on hold during that time
- 1:50when ICUs and hospitals were just full of patients that time.
- 1:55We recovered from that pretty well. Didn't go back to the numbers we had prior,
- 2:01but then the GLP-1s came out.
- 2:04And so that, you know, that's not, it's not surprising that.
- 2:10When something simpler, if you will, honestly, was there, is available instead
- 2:16of something that seems so terrifying to people like surgery.
- 2:20But the truth is that surgery still remains the most durable treatment for the disease of obesity.
- 2:27I think that's one thing I want to make sure that we kind of,
- 2:29we focus on as we talk today is that we're talking about a disease.
- 2:34We're not talking about a problem, not talking about a choice,
- 2:37talking about a disease.
- 2:39And obesity is no different of a disease than cancer is a disease.
- 2:45And, you know, you're asking about the medications and I love the way you phrased
- 2:50the question is that are we getting to a point of complementary,
- 2:54you know, medicine and surgery? And we are.
- 2:57We're seeing that, and you probably watched, there's tons of ads and everything
- 3:02else, so much media about medications.
- 3:05Medications are getting better. They're getting better and better and better.
- 3:08But they are a lifelong treatment requirement. You will always have to be on
- 3:15that medication so far because nothing changes people.
- 3:19It is just an adjunct or an augment to what their body isn't doing.
- 3:25Whereas surgery has, as it alters the anatomy, it also alters the physiology
- 3:32and the metabolic rate of the patient.
- 3:36So there's definitely a benefit there.
- 3:39One of my good friends out at, actually at Yale now, Dr. John Morton said,
- 3:44you know, we were, we were GLP-1s before they were cool.
- 3:48And which is true because surgery itself has an opportunity to let the body
- 3:54naturally produce the amount it's supposed to.
- 3:57And so most patients that do have surgery do really well compared,
- 4:02you know, to, to not for sure.
- 4:05But it has always seemed so scary, I think, to people. And it's just,
- 4:09it's really not when you take the time to hear about it.
- 4:13The GLP-1, you know, as it's come out, well, it definitely brought our volumes down.
- 4:20I would say if we look at 2022 to 2024, during the annual meeting we had of
- 4:26the American Society for Metabolic and Mediatric Surgery in San Antonio this
- 4:29year, which I actually had to be the president of at that time,
- 4:32happened to be in my own town, so it was cool. I heard it went well. It was great.
- 4:38We released the numbers at that time showing from 2022.
- 4:44To 2024, we've seen a decrease of about 40% of our volumes.
- 4:48So it was a real difference. And from 23 to 24 is about a 19% difference.
- 4:55So that's cumulative for those two years. The thing is that,
- 4:59well, it's a little frustrating at first for those of us doing surgery and,
- 5:03you know, treating this disease.
- 5:04What the medications have done without a doubt that we in surgery haven't been
- 5:08able to do was raise awareness that it's a disease, right? So more people now
- 5:13say, oh, there's a pill for it or there's a shot for it.
- 5:15That's a disease now instead of it's a problem. You know, people won't treat
- 5:18problems with pills that level.
- 5:21Not obesity and not other diseases. Or they treat diseases, but don't treat
- 5:25their problems. So like, you know, hypertension, yeah, people are on medications.
- 5:29But the cost is different, right? It's a very different thing.
- 5:32I was talking to a general pediatrician the other day, and she says that she
- 5:37gets asked about GLP-1s often.
- 5:40And she tells the families, you would need to see endocrinology.
- 5:43So if it's indicated for your child, then let's go that route.
- 5:47But if it's just, if it's something your teenager wants to be a little bit more
- 5:52thin or you think that they would benefit from, I'm not going to prescribe that.
- 5:56Do you think that that's a good way to handle it?
- 5:59Yeah. So I do absolutely believe that there are specialists involved.
- 6:04Now, endocrinologists have training in the disease process for sure.
- 6:09There are those individuals who are American Board of Obesity Medicine certified, ABOM, A-B-O-M.
- 6:17And so that, and that, that is open to anyone. That's open to surgeons,
- 6:21family practitioners, endocrinologists, you know, so internal medicine,
- 6:26the whole gambit of individuals can sit for that exam.
- 6:30And, and I would say that's someone who you're probably going to do better with.
- 6:34I'm not, not to discredit any family practitioners who haven't done that.
- 6:38If they're comfortable treating the disease, that's great.
- 6:40But maybe they are uncomfortable using the entire ornamentarian of the medications.
- 6:45And there are old medicines that used to do pretty well, and they don't maybe
- 6:49compare to the new ones today, you know, and that's okay.
- 6:53But someone who has all of that in front of them and has comfort with each of
- 6:57those is probably the best person to help, you know, you through your journey
- 7:02as an adult, through your child's journey as they're going from one point to the next.
- 7:07The American Academy of Pediatrics recommends considering the full spectrum
- 7:11of obesity treatment, including metabolic and bariatric surgery.
- 7:16What specific criteria-rich BMI, thresholds, comorbidities, age should pediatricians
- 7:23be using to decide who to refer for evaluation?
- 7:27Yeah, that's a great question. So if you look at, you know, and I'll bring up
- 7:32an updated. So in 1991, the NIH released criteria on metabolic,
- 7:39it was only called bariatric surgery then.
- 7:42We added the metabolic component of it in about 2012, or 2010, I think it was.
- 7:48And so when you look at that, the BMI previously used to be a BMI of 40 or above,
- 7:55with no comorbidities, or a BMI of 35 and above with hypertension or sleep apnea or type 2 IADs.
- 8:01Well, in 2022, the American Society for Metabolic and Bersetic Surgery,
- 8:06and IFSO, which is the International Federation for Surgery of Obesity,
- 8:09released a joint statement on criteria.
- 8:12And that criteria changed the BMI to 35 and above with no comorbidities or 30 to 35.
- 8:18So we definitely lowered that down. And then in the Asian population,
- 8:22a BMI of 27 is sufficient to actually qualify for surgery.
- 8:27So if someone says 27, that's not a lot, but we're talking about a metabolic
- 8:30disease. We're not talking about a weight or a BMI, which BMI is the easiest thing to do.
- 8:38It's definitely not the most reliable, but it's what we've gone after now in the pediatric world.
- 8:45The actual criteria is looking at those, the children who are a higher percentage
- 8:51of their, of the 95th percentile.
- 8:54And so that changes when we're looking at adolescents. And, you know,
- 8:58the American Academy of Pediatrics, they support us because we worked with them
- 9:03on developing those guidelines.
- 9:05And in part is what we know is that like the Tanner staging does not,
- 9:10you know, having metabolicometric surgery does not affect that.
- 9:13So it's okay to proceed with surgery earlier because the earlier we get to the
- 9:19disease process, the more long-term effect we have on it, right?
- 9:25Many pediatricians still think of bariatric surgery as a last resort,
- 9:29and a lot of misconceptions persist among both physicians and families.
- 9:33What are the biggest misconceptions you wish they'd stop believing? Yeah.
- 9:38Well, I would say the first one you can highlight is that it's a last resort because it's just not.
- 9:48When it's a last resort, that is what we're doing to react. So it's reactive medicine.
- 9:54And reactive medicine isn't really the best medicine when we practice it.
- 9:58Preventive medicine is what everybody talks about. And that's what pediatrics
- 10:03is all about in so many ways, right?
- 10:05So when you're doing a surgery to prevent further, you know,
- 10:11decrease in, whether it be life, length of time, whether it be other conditions
- 10:17that they're going to have, I mean, you're trying to stop those.
- 10:20And why wouldn't you? I mean, we live in South Texas.
- 10:23We have a very high incidence of type 2 diabetes in the general population here.
- 10:30But additionally, one of the highest areas concentrated in adolescents.
- 10:35And with surgery, and I don't want this to be surgery-centric,
- 10:41I really don't, but obviously as a bariatric surgeon, you know,
- 10:44this is what I've done for my life for 20-something years.
- 10:47Surgery is still the most durable treatment for type 2 diabetes, period, period.
- 10:54And the earlier we get to it, the more likely we are to put it into remission. So...
- 11:00Those kids who've been dealing with diabetes, let's say, since they were 12, 13 years old,
- 11:06and they finally reach adulthood six years later, seven years later,
- 11:10and qualify potentially for surgery because people didn't want to consider it then.
- 11:16They've had at least six or seven years of diabetes just running rampant in
- 11:22their body and it is more challenging to control that at that time than it is
- 11:29to control it at a year into it,
- 11:31and so if someone had an opportunity to be off medications and not have to take
- 11:37that and all the side effects that go with all the meds,
- 11:40that would be the that would be a much better opportunity And so I think that's
- 11:43where we have to kind of help individuals get through there.
- 11:46The other thing is, I think, unfortunately, as someone who's in the media,
- 11:51you know that the media, what's out there are shows that are there for the,
- 11:56you know, what's the right word I'm looking for? Shop value, right?
- 12:00And so people see like— The worst of what's happening, or sometimes the best.
- 12:04Yeah. And so, I mean, there's a title of a show, and it's, you know,
- 12:07My 600-lb Life. I'm not advertising anything that anybody probably is not aware of.
- 12:12That's the misconception that you have to be 600 pounds before you should qualify
- 12:15for surgery. That's just not true.
- 12:17You know, I kind of told you that the criteria in terms of the BMI,
- 12:21those are low BMI's when someone would qualify for the surgery.
- 12:24And we have a much better handle on caring for individuals when we get that opportunity.
- 12:30Now, meds, as I said, they're doing really well, but the meds can't be stopped.
- 12:34Whereas surgery, if you do it early enough, maybe that's all they ever need.
- 12:38But if you kind of give me the latitude to talk about it as like cancer,
- 12:44I think most people understand if they had the disease of cancer,
- 12:47they would come to the surgeon, to the medical doctor. They would absolutely
- 12:51say, I have disease, please cure it.
- 12:54And, but when people think about obesity, it's an outward appearing disease.
- 12:59And there's been so much bias in our society that it's a blame people for having
- 13:04that disease. And that's not what it is. They didn't, they didn't ask for it
- 13:08and they didn't do it to themselves necessarily.
- 13:11So, but cancer can be treated with medication only and somebody is cured or
- 13:16at least in more mission, or they get a surgery only and it's fine, or they might eat both.
- 13:21And that's the world we live in today with the disease of obesity.
- 13:24Medications are doing really good. They can be a good bridge to get to surgery.
- 13:28They might be on a medication and just do swimmingly and not eat anything else.
- 13:33They might get surgery and never need anything again. or maybe because it's
- 13:37a really chronic, unrelenting disease, they need both. And that's okay.
- 13:43Do you have any advice for pediatricians regarding when they're getting inundated
- 13:49with parents asking about these medications and their child is not obese?
- 13:55It's a great question. So I think as, you know, the more informed they can be,
- 14:00the better off they will do.
- 14:03There is so much of a push, as you said, from the media.
- 14:07And we'll be honest with you the medication companies the pharma companies they
- 14:11have a lot of money that they can put forward to that that's why you know there's
- 14:16commercials Super Bowl commercials.
- 14:19And also it's a little unregulated to a degree right I mean not the pharma companies themselves but
- 14:24you have groups on on that you can go get these medications from with an online
- 14:29consultation with no one ever really
- 14:31watching how you're responding to the medications that's a little scary.
- 14:35I mean, if you decided to Google my blood pressure and decided to go onto some
- 14:39online site and just start picking blood pressure medications at will,
- 14:43that'd be a little scary.
- 14:44I think people would think that's crazy, but then when we talk about it with,
- 14:48you know, medications for, you know, losing weight, and so many people are learning to link it right.
- 14:54Yes. I was at dinner with one of my friends. We've been friends since third grade.
- 14:58And she looked different. I mean, she didn't look like she needed to lose any
- 15:02weight, but she had no interest in the food we were eating.
- 15:05And that's one of the things I love about her is this, like, she loves a great meal.
- 15:11And then she mentioned she's on the GLP-3s that aren't approved.
- 15:15And her functional medicine doctors prescribed them for her.
- 15:19And she just wants to lose weight with them.
- 15:23Yeah, well, that's when you're trying to keep up with all those. You're exactly right.
- 15:26So, you know, there's the GLP-1s, and then there's the combo therapies and GIPs
- 15:30and GLP, and then there's this GLP-3, which is research-owned.
- 15:34And by the way, I find it very interesting because that I think in the adolescent
- 15:40and sort of young adult area, you see that there are companies targeting people
- 15:45specifically under the guise of research.
- 15:49And actually, I was looking at this two days ago, and those research compounds,
- 15:56can't call them medication because they're not FDA approved,
- 15:59says very specifically, for research purposes only, not for human or animal use. Wow. Yet.
- 16:06Every one of them is being sold to a person who's injecting themselves with it.
- 16:11And that's a little scary. Yes. So, again, I understand, and maybe with the
- 16:17area of cancer, people might want to try.
- 16:21Other therapies, right? Other holistic options.
- 16:25And I would never tell anybody not to do it. You do everything you can to put
- 16:30your cancer remission or cure it, right?
- 16:32But here's known things. So I find it a little scary that people are treating
- 16:37themselves with sort of, there's not randomized controlled trials.
- 16:42I mean, those GLP-3s sound promising, but they're not even out.
- 16:46And also, if you're getting it from a research company, you don't even know what it is. Right.
- 16:53And she, yeah, she just talked about the food she was not interested in.
- 16:57Which was what we had in front of us. And then was so tired,
- 17:01she had to leave early, you know.
- 17:03Well, and that's one of the things I think. That's one thing that the medications
- 17:06had done that gave a term to something that we've been seeing in metabolic retic
- 17:12surgery for, you know, 30-plus years.
- 17:15When I was doing surgery way back before GLP-13, when I would do a gastric bypass
- 17:21on a patient or a sleep gastric on someone, after surgery, more than 80% of
- 17:26patients said they weren't hungry. They just didn't feel hungry.
- 17:28And I get that's a good thing. But I said, you know, we would talk about having
- 17:32a healthy diet, which meant eating about five or six small meals a day,
- 17:37giving your body the fuel it needs all day long, right?
- 17:41You don't run your car to, well, you try not to run your car until it's on the
- 17:44last fumes. You try to fill it up, fill it up.
- 17:47So you're doing that same thing with your body, but the individuals,
- 17:52so this term that came up with the GLP-1s is food noise.
- 17:56And that's what I think, surgery has been quelling this food noise for years,
- 18:01since we've been doing it. We just didn't have that term.
- 18:04But now when someone has a GLP-1, they aren't, it's not even an obsession,
- 18:10it's just they're not thinking about it.
- 18:11The food is so far from moving, which is what GLP-1 does.
- 18:15So it slows your stomach But it makes you not hear that I thought that was kind of dramatic.
- 18:21This one doctor told me that he tried the GLP-1s and that he couldn't drink
- 18:27enough water during the day and he got a kidney stone.
- 18:30And so he stopped taking it after a month. He said for him it was not good at all.
- 18:34You know, I have colleagues, you know, in our metabolic and pediatric surgery
- 18:37world who are using them and they feel good about it.
- 18:43They're being cautious and they're careful. But you're absolutely right.
- 18:46There is still data that is unknown about these, you know, medications and what
- 18:52their long-term effects are.
- 18:54And I think that's the part where we're going to see some interesting information
- 18:59over the next couple of years.
- 19:01We've definitely seen it with certain medications causing pancreatitis.
- 19:05You mentioned gallstones. I mean, there's gallstones, which certainly you can
- 19:07do too, but it's, again, you know, that's an issue.
- 19:11I'm going to talk about blindness. I don't want to talk about all the— That could be a side effect?
- 19:15Yeah, absolutely. Really? Blindness? Yeah. Didn't know that.
- 19:18So it's very interesting.
- 19:20Are there lots of reports? No. And this is the same thing. I'm sure somebody's
- 19:23like, well, surgery, you know, there's leaks and there's this.
- 19:26But the reality is that, you know, if you look at our data, here's what I think
- 19:30is a striking difference, is that the reported weight loss with medications
- 19:36currently are all off of the randomized controlled trial data. Okay.
- 19:41Well, that, and which is good. It's good data.
- 19:44But it is randomized control.
- 19:46Control is the big word right there. Whereas if you look at real world data, that's different.
- 19:52So the weight loss with individuals on those medications in the real world setting
- 19:57is less. It's different.
- 19:59Surgery, we don't have a ton of randomized control trials.
- 20:04So most of our data that we're publishing is real world data.
- 20:07And so most of the things you hear about surgery are real-world data quoted.
- 20:11And so I think that's the difference. And, you know, when we're trying to get,
- 20:17that's definitely apples and oranges. You're trying to put them together.
- 20:20So how do you determine whether an adolescence is a better candidate for GLP-1
- 20:26therapy, bariatric surgery, or both?
- 20:29You know, that's, again, great question, because I think you have to individualize
- 20:35the care for that individual.
- 20:38And in the disease of obesity, we have not yet done a good job of characterizing
- 20:45what I would say are the phenotypes of obesity.
- 20:48So in cancer, we can say you have pancreatic cancer, you have breast cancer,
- 20:52you have stomach cancer, you have different cancers, and we know kind of how
- 20:55they work and what they do.
- 20:58Right now, we're treating obesity as a disease, and there's a spectrum,
- 21:03right? Someone who's a BMI of 37 and has diabetes, high blood pressure,
- 21:07sleep apnea is different than somebody who has a BMI of 70 with no other conditions.
- 21:14They're both in a severe form, but just very different.
- 21:17So understanding what are the needs
- 21:21of that individual and how can we best support them in all those ways.
- 21:27Again, just if we don't coordinate the care, because cancer care is coordinated and people do well.
- 21:33If we don't coordinate the care in the obesity space, we're going to leave patients
- 21:38behind. And that's not right.
- 21:41What do you say to a parent who says, but my teenager's body will be permanently
- 21:46changed by this surgery, so wouldn't medication be better?
- 21:51Well, you know, great question.
- 21:55And yeah, there will be an alteration of the body, but they have a disease.
- 22:03And so when a child comes in with a tumor, like a Williams tumor or something
- 22:09along those lines, and I'm pulling from medical school stuff,
- 22:11okay? It's been a long time since I've seen that stuff, but I remember that's a kid's tumor.
- 22:15When you have a tumor like that, and surgery is going to alter their body.
- 22:19It's going to take that away.
- 22:22And no one blinks an eye because you're treating the disease.
- 22:27So this disease of obesity permanently altering the body can lead to a positive
- 22:33effect that saves them from all the sequela of bad things that happen with the disease of obesity.
- 22:41And usually in adolescence, we tend not to go to the more extreme,
- 22:46what I would call is a terminal operation, which is the gastric bypass.
- 22:50So it's a great operation. It's the gold standard. It's what we've done doing for 60 plus years.
- 22:55When you look at it, but it is more altering, whereas the sleeve gastrectomy
- 22:59just takes out a portion of the stomach, no alteration of the anatomy,
- 23:02essentially, other than the removable part of the stomach, but everything else is in continuity.
- 23:07We have options to do things later with the sleeve, for example.
- 23:10Whereas the bypass currently today, there's not a lot of options to continue on that journey.
- 23:15And so when I see patients that are younger, I lean towards that because I know
- 23:20that this chronic unrelenting disease is going to be there for their whole life.
- 23:24And I want to have options later if necessary. And the medications,
- 23:29that's just it. They're not altering anything.
- 23:32You know, they're just, the medication are just providing what the body isn't doing well with anyway.
- 23:39But what we don't know is that's a constant, ongoing, like, you've got the GLP-1,
- 23:46so it's going all the time, all the time, because it's in your bloodstream.
- 23:49Whereas with surgery, when we've done surgery, your body naturally produces
- 23:54the amount of GLP-1 it needs for that moment, and then it stops it for a while.
- 23:58And then it produces and stops. But that's all your body's regulation.
- 24:02Whereas the other one is just a constant barrage of that. And will the long-term
- 24:08effect of that, what will that be?
- 24:10I don't know. I mean, I don't have that crystal ball, but I do have concerns
- 24:14that either there'll be resistance because maybe the medication dosing is going
- 24:19up for each individual, or maybe the body just doesn't respond to it at all anymore.
- 24:25Or maybe there's a potential that, and if you look the disclaimers,
- 24:29if you have certain disease processes, you shouldn't be on a GLP-1 because it
- 24:35may exacerbate it or make some of it a rotten source.
- 24:39Rich, how did the outcomes compare between today's GLP-1 medications and bariatric
- 24:45surgery, broadly speaking, in terms of weight loss and remission of conditions
- 24:49such as type 2 diabetes, hypertension, sleep apnea, and fatty liver disease? Yeah.
- 24:55So when you look at, you know, a blanket statement, surgery outperforms them all.
- 25:01That having been said, and that's the general. Now, if you look at each of the
- 25:04individual surgeries that we do, some outperform by a lot, and some are,
- 25:10they're almost, they're not neck and neck, but they're close to each other.
- 25:13The most, with the current,
- 25:16most effective medications, the GLP-1 is the trisepitide, which is that combo, right?
- 25:23That one does really well. And so when you look at that, that is not quite as
- 25:28good as a sleeve gastrectomy, but it's close.
- 25:32But then the gastric bypass or the duodenal switch or CEDES,
- 25:36we call that, this is a single anastomosis duodenal ileostomy with a sleeve.
- 25:41That's a very aggressive operation that if someone has bad type 2 diabetes,
- 25:46I mean, that's going to aggressively treat it.
- 25:49Most of our surgeries for someone whose diabetes has been five years or less,
- 25:53when we do the surgery, we put their diabetes into remission.
- 25:57In fact, they're off their medications the next day. So that's pretty dramatic.
- 26:02And we are seeing the reduction in sleep apnea, hypertension,
- 26:06cholesterol, fatty liver.
- 26:08You know, it's interesting you bring up the fatty liver thing because here at
- 26:10UT, we're really blessed to be working with our transplant team.
- 26:15It's an incredible team. They're incredible. And we've done,
- 26:19we've actually published on this now with living donor liver transplants.
- 26:24We are doing sleeve gastrectomy at the same time.
- 26:27And those individuals, now these are individuals whose BMI was over 35 and they came to see us.
- 26:32Their disease process in their liver, their liver guff, was a fatty liver disease
- 26:37that then went on to some of the newer terminology, MASH and MAFOLD,
- 26:41you know, which is the metabolic associated fatty liver disease,
- 26:45which then went on to cirrhosis.
- 26:47So the reality is we want to prevent that new graft from getting that same disease
- 26:55process. So that's why my friend Renee Hilton in Georgia, I love her. She's hilarious.
- 27:02I was telling her about this program. She said, that's amazing.
- 27:05It's amazing because she's like, why would you buy furniture and put it in your burning house?
- 27:12Which is true. This liver is the new furniture. And if you haven't changed anything
- 27:17about them, but take out the old liver and put in the new liver,
- 27:20you've not changed anything about their metabolic disease that's going to make
- 27:23that new liver sick again.
- 27:25So let's change the paradigm.
- 27:28And these patients who we've done it on, and I just saw one of them,
- 27:32he was at his two-year visit last week.
- 27:34He is like, he was absolutely against the idea of surgery, of rather of metabolic
- 27:40surgery. until we did the sleeve.
- 27:42But he was completely fine with having his liver gripped out and put in a new
- 27:46one, right? But I was like, well, what are you afraid of here?
- 27:50Because he had sleep apnea, hypertension, diabetes.
- 27:53And the new liver doesn't change that. But the surgery we did changed that.
- 27:57And so doing it together.
- 27:58So now he's, I mean, oh yeah. He's like, I want to be your poster child.
- 28:02I love this. This is like, it's the greatest thing I've ever done in my life. Wow.
- 28:06And I would say most people, by the time they're getting to surgery,
- 28:10the most common thing that's ever said to me in the last 25 years is I wish I'd done it sooner.
- 28:16And that's a great analogy about the furniture. So what happens when patients
- 28:21discontinue GLP-1 medications and how does that durability compare with weight loss after surgery?
- 28:28You've got a lot of great questions. Oh, thank you. So that is,
- 28:31when you think about the medications, if you stop them, you,
- 28:37again, you haven't changed anything other than you've supplemented the individual.
- 28:43So when they stop, they're going to have weight gain. And in fact,
- 28:46most studies, almost all studies, people regain all the weight back.
- 28:51The hard thing about the medications currently is that at about six months,
- 28:5750% of people taking the medications have stopped.
- 29:00And at a year, about 70% of the people have stopped.
- 29:05And there's different reasons. Side effects, you and I were chatting about it a little bit before.
- 29:10Cost, insurance coverage anymore. So I was doing some visits on the Hill this
- 29:16last year. And we had a patient as one of our folks that were going from,
- 29:20you know, senator and congressman, you know, back and forth around.
- 29:24And it struck me that she had had really great success with her GOP one.
- 29:28And she looked great. She was feeling great.
- 29:30But she was so anxious and had so much fear because her insurance stopped covering it.
- 29:38So here's a taste of great success. And now we take it away.
- 29:42And so that is heartbreaking.
- 29:46Drinking. We don't do that to surgery. You know, insurance company approves it to start with.
- 29:51They don't get to unapprove it after you've already had it, right?
- 29:54It's, so it's yours to key.
- 29:56Now, hopefully it continues to give you all that you need, but,
- 29:59but the durability kind of tying back to the durability of the question that you ask is with surgery.
- 30:05And again, if you just lump them all together, well over 70% of patients maintain
- 30:11their excess weight loss at five years.
- 30:15If you break it down by surgery, sleeve is more like about 55-60% of patients
- 30:22keep it off of five years.
- 30:24Gastric bypass is close to 80%. And at that SATI or DS, it's more like 90-95%.
- 30:30So, it's pretty dramatic.
- 30:32I have another friend who, and she's lost a lot of weight on that GLP-1s.
- 30:38And she says she can't keep weight on now. Like it's becoming,
- 30:42her weight's becoming dangerously low.
- 30:44And then I asked her, well, how about try, I mean, can you stop taking the medication?
- 30:49And she said, I know I'll gain everything back the week I do that,
- 30:53you know, so I'm not ever going to. Right.
- 30:55Right. Yeah, it creates a, again, these are the unintended consequences of a
- 31:02rapid uptake of something.
- 31:06And I'm not going to call it a fad. It's way beyond a fad. And like I said.
- 31:10And it's a godsend for some people, of course. Absolutely. And so there's this
- 31:14fear that they've gotten something they've never had before.
- 31:17You know, we like to say that people who are taking the medications are trying on surgery.
- 31:23But they're getting a sense of what surgery can really do for them.
- 31:26Wow. But if they have to stop it, then there's this, to your point,
- 31:31there's this whole fear because the individuals who are going, they're leaving.
- 31:37I would say most people, when they're leaving where they started,
- 31:41they're not leaving their disease.
- 31:44They're leaving from a place of bias and stigma that is so horrible that they
- 31:50have an incredible fear of having to go back to that.
- 31:53They're not afraid of necessarily not being able to get on the roller coaster
- 31:57again. I mean, that is part of it.
- 32:00They're afraid to go back to all the things.
- 32:05The person who can't go through the grocery store and go to the dessert aisle
- 32:10without being judged for picking
- 32:12up a thing of ice cream because outwardly you can see their disease.
- 32:17I mean, some people might look at someone who's buying cigarettes and say,
- 32:22you know, oh, they probably shouldn't smoke, but they don't see their lung cancer
- 32:26in their body versus doing that.
- 32:28So it's just, it's not the same stigma. It's this disease of obesity has such a horrible stigma.
- 32:35And I think that I know patients are afraid.
- 32:38Are GLP-1 medications being used before surgery, after surgery,
- 32:43or both? And how do you see these therapies working together?
- 32:46Yeah, they are. And in fact, I think it's a great way to do it.
- 32:50I alluded to the word bridge before.
- 32:53So in my presidential address, this is one of the things I talked about is.
- 32:57We, you know, treating a disease like obesity is, it's like this,
- 33:03this book by Simon Sinek, it's called The Infinite Game. I don't know if you've
- 33:06ever read it or heard about it.
- 33:07It's a great book. I highly recommend people read it. It's such a,
- 33:10it was such an eye-opening thing for me.
- 33:12The Infinite Game is that you are in the game to play the game continuously.
- 33:17You're, you're not trying to win or lose. You're just trying to keep playing.
- 33:20When we were kids, I'm going to guess we're similar age, you'd go out on the
- 33:25street and you'd play and you'd play until it was dark, but you wanted to keep playing.
- 33:29You may not be keeping score, you just played to play and it was fun.
- 33:32And so the infinite game is doing that. The finite game is trying to win and
- 33:38just there's a winner and a loser there.
- 33:40And in medicine, that's not the place. We need to be in the infinite game.
- 33:43We need to just always trying to do better and trying to continue what we're doing.
- 33:48When it comes to the medications, you know, people who play the infinite game,
- 33:53they don't look at their competitors.
- 33:56They can look at their competitors, but they need to learn from them.
- 33:59They don't need to necessarily compete with them.
- 34:02I would say that's what we have to do in our world today is we need to not fight
- 34:07with the medication companies when it comes to surgery and medications.
- 34:10We're not, it shouldn't have to be either or.
- 34:13It's that there are choices for your disease and we can help you with that.
- 34:17And now we do see there is more of this use of it before surgery, get through surgery.
- 34:25And in those people who we've determined have a really severe form,
- 34:28we keep going. We keep doing it.
- 34:30So they need them both, just like cancer.
- 34:32They call that neoadjuvant therapy.
- 34:35Surgery and then adjuvant therapy. And that's exactly how we need to look at
- 34:39the medications and surgery in a common, you know, in a synergistic therapeutic model.
- 34:45How do you help families navigate the decision of maybe they're worrying about
- 34:50surgery versus worrying about keeping their teenager on medications for years or a lifetime? Yeah.
- 34:57You know, the nice thing about the care of obesity, and certainly in surgery,
- 35:04we have been doing comprehensive obesity care for it. That's how we do it.
- 35:10And so we work with dieticians, we work with psychologists, we work with,
- 35:14you know, work the primary care doctors.
- 35:16We all work together to ensure that the patient is getting the best treatment all around.
- 35:22And when it comes to, you know, the little difference in the adolescence part
- 35:26is that, you know, there's more counseling time spent doing that,
- 35:29ensuring that everyone understands, ensuring that there's support,
- 35:33getting rid of the blame, blaming the parents for, you know,
- 35:37giving them junk food or blaming the parents for, you know, a more sedentary
- 35:41lifestyle for their child or blaming the parents because,
- 35:44turns out, interestingly enough, obesity is a, you know, hereditary disease.
- 35:49And so, but people just see individuals suffering from that disease with,
- 35:54you know, junk food and all these other things, whereas that's not the case.
- 35:58So families are counseled and, you know, so it's the longer process when you're
- 36:04in the adolescent world for surgery.
- 36:07But it absolutely can be effective. And actually, oftentimes it benefits the
- 36:11entire family. Brilliant.
- 36:14Insurance coverage and access are often the real barrier pediatricians run into
- 36:19when trying to refer a patient. What should they know about navigating that?
- 36:23Yeah. So I think we've actually done a really good job in our world today,
- 36:29especially from a surgery perspective.
- 36:32Most insurers actually do cover surgery. Medications are still being challenged by that.
- 36:39So from an access perspective, here's what I would say. I would say,
- 36:43at least on the surgery side of things, just refer to the surgeons.
- 36:48Let us deal with that. That's what we do.
- 36:50You know, medications, getting the referrals, that can be a challenge,
- 36:53or getting authorizations, rather.
- 36:55In surgery now, like I said, we've done such a good job on our access to care,
- 37:01so there's a lot of access.
- 37:02The problem is utilization.
- 37:05So everyone has Peloton.
- 37:09But how often are you using it? And that's the thing. So we've given everybody
- 37:14an opportunity to have that, but it's just people aren't doing it.
- 37:18And there's a lot of reasons why. I do have a Peloton. And I do use it, though.
- 37:23But not as often as I should. I've got an elliptical sitting in the bedroom
- 37:27that it is an amazing coat rack.
- 37:32It's the greatest intention, right? But it's not getting too—but that's there for people.
- 37:37And I think you asked a little earlier, maybe that's a good myth,
- 37:40too, is a myth that surgery is not a covered benefit is actually not accurate.
- 37:46Most insurance plans are pretty good about it. Now, if you're on one of the
- 37:50state, the exchange plans. Oh, exchange plans.
- 37:53Those don't because currently obesity is not one of those diseases that is considered
- 37:59an essential health benefit, which is crazy.
- 38:02And so we're working on the national level to fight that.
- 38:05In fact, that's one of the things we did all last year. We're pushing forward
- 38:08this year with even more on that.
- 38:10So if we can get at the federal level to change so that the disease will be
- 38:15seen as the essential health benefit, that will filter down to the states that
- 38:19have those exchange plans. Is that going to happen?
- 38:22I believe it will. Do you want to say anything else about you mentioned it helping the entire family?
- 38:27Yeah. Yeah. Well, so, you know, I mentioned my buddy, John Wharton,
- 38:30he, when he was at Stanford, they did a study looking at, you know,
- 38:34so those individuals who had surgery and then they followed their family, their spouses and kids.
- 38:39And what they found was that those individuals who had the surgery had a pretty
- 38:44good normal progression of their weight loss as expected with surgery and also
- 38:48found that the families lost about 13 to 15 percent of their weight just by,
- 38:54being a part of that one person's journey. Wow.
- 38:57It's just that they're supporting, they're changing the ways they eat,
- 39:01maybe they're exercising more as a family.
- 39:03So that definitely you see that impact when you have that supportive structure
- 39:07within the group. So absolutely. Okay, that makes sense.
- 39:12Has the popularity of GLP-1 medications changed the surgical candidates you're seeing?
- 39:17Are today's patients different than they were five years ago? They are. Yeah. Yeah.
- 39:24I, again, I also address this, that the world of surgery and the treatment of
- 39:31obesity, we're evolving in that way.
- 39:34You know, the cardiothoracic surgeons in the 90s and 2000s dealt with,
- 39:40you know, they were the all coronary artery disease. They took care of it.
- 39:43And then what happened was the stents came along.
- 39:45Very easy for people to do. They have cardiologists and interventory,
- 39:48all these people doing it.
- 39:50So they struggled, but they did define the best way. They took on more complex
- 39:55disease. That's where we are today.
- 39:57We're still in the metabolic and metric surgery world. We're going to still be the revision people.
- 40:02We're still going to be people who take care of BMIs of 50, 60, 70, 80.
- 40:06I mean, medications just don't
- 40:07touch those people, just not going to make an effect for a long time.
- 40:11So we're going to just own a different subset. I would say the patients,
- 40:15I'm not seeing as many BMI 42, you know, with maybe high blood pressure or one thing.
- 40:22I'm seeing a lot more severe disease.
- 40:25And that's okay because we're still here to take care of everyone.
- 40:29And I think that there will probably be a, there is, well, I'm already starting
- 40:32to see a swing back in our practice of an increase in our number of referrals
- 40:37in patients seeking metabolic rheumatic surgery.
- 40:40So if there's one message you'd like every pediatrician listening today to remember
- 40:45about treating adolescents with severe obesity, what would that be?
- 40:49It's never too early to start.
- 40:52Think about it. If there's questions, reach out. We'll help you.
- 40:57We'll help you navigate it. Don't be burdened by the process of whether they
- 41:02have a benefit or not. If they don't, we'll work with that and help you figure it out.
- 41:06Maybe there are other plans that they can look at. Maybe when the next year
- 41:09comes around, the family can adjust the plan that they're on or look for that
- 41:13to make sure the coverage is there.
- 41:15But don't be afraid to do that. You know, you just don't let that be the barrier.
- 41:20And don't let obesity as a disease be a barrier to the conversation about treating
- 41:25someone with a disease of obesity.
- 41:27It is a disease. And so some people say, if I bring it up, it's embarrassing.
- 41:31It's not embarrassing. In fact, you not talking about that it only makes it worse.
- 41:36You're the individual who can actually talk about that disease actually brings
- 41:42relief to the patient who knows that they have this disease. They just are way.
- 41:46Actually, they don't have this problem. I'm putting air quotes here.
- 41:50They have this problem, but they actually have a disease.
- 41:52And so there's a there's a process there. Help them. Help them with their disease.
- 41:57And I love the empathy coming through with with all this way you're talking about obesity.
- 42:03I know that helps the patients that you see and the families.
- 42:06We have dieticians that we work with that are just spot on on fire. They're amazing.
- 42:12And they have that empathy and compassion for individuals who are dealing with
- 42:16this disease. So they are able to work through that process and help them.
- 42:20And some people really want the, please give me the blueprint. And then I will build.
- 42:28I have this furniture from Ikea. Help me build it. And other people just need the concept.
- 42:34And the people that we work with are able to cater to both.
- 42:38And let's be honest, we're talking about adolescence too, but as an adult,
- 42:42most adults have gone through all the diets and all the things.
- 42:45Most of what you're telling them, they've already heard 100 times.
- 42:48So kids, maybe they're starting to hear about it.
- 42:51But also sometimes it's so restrictive that it becomes that they actually,
- 42:56in fact, using the word diet, when I say diet, I'm not even talking about like
- 42:59a Weight Watcher style. I'm talking about like, this is my diet.
- 43:03My diet is I eat this, I eat that, I eat this. That's what I mean.
- 43:06But I remember one of my dieticians was like, you're using such a bad word.
- 43:11When you say diet, that is just like, it's like saying a bad word. They don't like it.
- 43:17Finding another way to talk about meal plans, you know, that kind of thing,
- 43:22so that individuals can focus on the good.
- 43:25And pediatricians are seeing so
- 43:28many patients a day. Often they see 40 patients a day. When is it time...
- 43:35To say this is when you need to look at surgery. I know we've gone over this,
- 43:38but just a quick review about BMI and how long they've been trying,
- 43:43changing eating patterns.
- 43:45Sure. I mean, the thing is, if you, you know, it's never the wrong thing to
- 43:51start with someone who, if you want to start on lifestyle changes and medications,
- 43:57just be aware that lifestyle,
- 44:00meaning, you know, diet and exercise,
- 44:03is horribly ineffective when
- 44:06it comes to treating me. But it seems like that's what everybody does.
- 44:10And it's just that's almost never enough.
- 44:14You know, The Biggest Loser was that show that they did diet and exercise. They did great.
- 44:19But that's fine if you have a personal trainer 24-7 and a chef 24-7.
- 44:24What happened to all those people after The Biggest Loser?
- 44:27They gained it back. And there was only one person who did it and they had surgery. Really?
- 44:31So it's, so that's, that's not effective, but you can try there. You can try.
- 44:36Unfortunately, you know, I get it. There's a time constraint.
- 44:39Right. And so the other thing is don't, don't also feel afraid that you're going
- 44:44to lose anything by sending them to a specialist whose, my entire visit is designed for this.
- 44:51It's my, my visit is not trying to treat the other 10 things and that.
- 44:57And also, if you're just treating their diabetes and their high blood pressure
- 44:59and their sleep apnea and their cholesterol.
- 45:03You're missing the one big thing that if you did this, you would at least quell
- 45:07most of that or treat it better, more effectively with less medications or maybe none.
- 45:13And then send them to the specialist, it doesn't have to be surgery specialist,
- 45:17tell them to obesity medicine specialist. Let them take their visit,
- 45:20which is designed for obesity too, help them through that.
- 45:24You're not going to lose a patient. You're just going to, you're going to gain a healthier patient.
- 45:29And you do surgeries at the UT Multi-Specialty Surgery Hospital and University Hospital?
- 45:34Correct. Yeah. We're working on the Multi-Specialty Research Hospital.
- 45:39We're in the process of getting that up and running for the metabolic and pediatric surgery.
- 45:43We've been doing the metabolic and pediatric surgery at University Hospital
- 45:46for quite a few years now. We've
- 45:48actually, we're an accredited center for metabolic and pediatric surgery.
- 45:51And so we're looking to expand that designation as well.
- 45:54And you may expand to adolescent surgery. That's our plan. That's our hope is we'd like to do that.
- 45:59So we're really giving the full comprehensive care. Now that that hospital has
- 46:03a, you know, women's and children's swing and we're working with our pediatric
- 46:06surgeons and pediatricians, we have a real positive hope to make that a redout.
- 46:11Yeah, I just can't emphasize enough that there are so many options out there
- 46:17for treatment for this disease.
- 46:19And, you know, here at UT Health, we are here to help and we have all the components.
- 46:27I would love soon, someday, to have our full comprehensive center where a patient
- 46:32can walk into the front door and get all of the services in one place to take care of them in that way.
- 46:38We may not have that building right now, but we have all the infrastructure
- 46:43and we will get people to the right place and we will not leave anyone behind. I love it.
- 46:49And here on Pediatrics Now, I love to focus on having a life outside of medicine.
- 46:54Do you want to mention what you like to do in your spare time?
- 47:00Well, I would say, unfortunately, the last two years has been a lot less spare
- 47:03time. And you're not on the elliptical. Okay, we've crossed that off.
- 47:08I really enjoy, you know, I love skiing. I love traveling.
- 47:12My mom was a travel agent. So while growing up, we got to do lots of different
- 47:16trips with mom on her like fam, They called them fam trips back in the day where,
- 47:20you know, I was going to check out, you know, properties and stuff. Doing the work.
- 47:24Someone's got to do it. She was working and we enjoyed it. Nice.
- 47:26I really, but I love traveling. And actually, you know, in my,
- 47:30you know, role at the ASMBS for the last couple of years, I've had a lot of
- 47:34travel and I do enjoy that.
- 47:36But getting the opportunity, you know, I love skiing, you know, getting outdoors.
- 47:40We actually just had a retreat up in Montana. Nice. I've never been there. It was gorgeous.
- 47:45My ski accident happened in Big Sky. It was so beautiful. It was a big sky.
- 47:48It was. Oh, yeah. So we went to, we actually were at the summit.
- 47:51It was a summertime. So we went to that summit resort.
- 47:54And yeah, I mean, I saw Bozeman Hospital. Oh, you're a little stuff. Yes.
- 47:59I almost went there, but I came back here for the surgery. I got to go down
- 48:02in one of the, you know, emergency. Oh, boy. Yeah. Yeah.
- 48:06So, you know, I like trying to do different things.
- 48:10But Bozeman's beautiful and big sky is so gorgeous and I want to go back. Yeah, me too.
- 48:16Nice. So skiing, what about any summer travel? Are you doing anything fun there?
- 48:20The summer travel I'm doing is all for work.
- 48:22You know, I'm actually, I was just down in Puerto Vallarta giving some talks. Oh, nice.
- 48:27That sounds like a rough job. Yeah, it was real rough. Yeah.
- 48:29I'll be going to Monterrey, Mexico coming up soon here. I'm actually going to,
- 48:33we have a retreat in Lake Tahoe.
- 48:36We have that IFSO group I mentioned is in Toronto.
- 48:39And I'll also be giving some talks in Oxford coming up in September.
- 48:43In England? Yeah. Oh, nice. Yeah, I've been a part of it. They have a bariatric
- 48:48meeting that they do every year.
- 48:49Oh, nice. It's last year's, but I've been there for the last,
- 48:51yeah. It's kind of cool being in Oxford at Christchurch.
- 48:55Yes. They have the dinners in that hall that Harry Potter was modeled after.
- 49:00Oh, wow. And drinking out of silver goblets. And I studied at Brasenose College,
- 49:06postgraduate study at Oxford, and studied Shakespeare in performance versus reading Shakespeare.
- 49:12Speaking of Shakespeare, do you have a favorite quote?
- 49:15Do you have a favorite quote from Shakespeare? Or just favorite quote,
- 49:18just from Dr. Richard Peterson or someone you like, a quote. I've got a couple. Okay.
- 49:25I love quotes. But I'm going to say, let's start with this one.
- 49:29And so there's a surgeon by the name of Wayne Meredith who says this,
- 49:33but my chairman says it more often than not. And I've lived this way for the
- 49:37last, you know, seven or eight years is presume virtuous intent.
- 49:42Now, what that means is that the person, so, you know, we, we had some Starbucks,
- 49:48right. And they actually made my order correct today. Right.
- 49:51But if they had given me this mocha with almond or something,
- 49:56it wasn't that they chose to do it and were trying to hurt me.
- 49:59So I presume that the person intended to do the right thing.
- 50:03Now that only doesn't change the fact that I've got the wrong drink,
- 50:06but it does make me not think that they're a bad person. So I,
- 50:10I try to live that way, presume virtuous intent.
- 50:13I think that's important. And then the other one is that if you're the smartest
- 50:17person in the room, you're in the wrong room.
- 50:21And, and my chairman's has a quote that it was more like, you know,
- 50:24the smartest person in the room isn't smarter than the room too.
- 50:27So I think those are, I just always learning and just know, I mean,
- 50:30I just, I don't, I don't live by being the, I don't want to be the smartest person in the room.
- 50:35In fact, it's kind of funny when I go out and if I'm traveling or whatnot,
- 50:39unless I'm at a surgery meeting, I usually don't tell people what I do.
- 50:43Really? It changes the dynamics sometimes. So I just like to be neat.
- 50:49But being a surgeon really is, it's at my core.
- 50:55And that's a great thing to think about, how the power of the intelligence in
- 51:00a room and as a team, how we can work better together. It goes to that diversity
- 51:05of thought, you know, the more thought that can be about something,
- 51:08there's things, a lot less things will be missed.
- 51:11Dr. Richard Peterson, Chief of Metabolic and Bariatric Surgery at UT Health
- 51:17San Antonio. This has been so insightful. Thank you so much for being here on Pediatrics Now.
- 51:23Don't forget to click on the link in this podcast for free credit that includes
- 51:27CME, MOC, and ethics credit, depending on our topic or podcast.
- 51:32Our website is PediatricsNowPodcast.com, and our sister podcast is Pediatrics Now for Parents.
- 51:39We'll have a shorter parent-friendly episode on that podcast.
- 51:43You can also find Pediatrics Now for Parents anywhere you get your podcasts.
- 51:47It's meant to be one less thing you have to say in the exam room.
- 51:51Coming up next week you've heard about it the lettuce outbreak we'll talk to,
- 51:58our pediatric infectious disease doctor dina sutter with some advice and we
- 52:02know you're probably getting asked about this and she's also going to talk about
- 52:06the rabies and typhus in san antonio and in other states,
- 52:12i'm holly wayment thank you for listening to pediatrics now i'll see you soon.