509-Gene Expression Noise in Development
Gene expression noise, driven by transcriptional bursting and RNA degradation, creates cellular variability essential for cell fate decisions. Advanced single-cell technologies now quantify these dynamics genome-wide, revealing how noise peaks before lineage commitment in embryos.
References:
Gene expression noise in development: genome-wide dynamics. Bax, Danique J.C. et al.Trends in Genetics, Volume 0, Issue 0
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The skinny
The skinny isn't ready yet — notes appear once the transcript is processed.