Chronic Urticaria Explained: BTK Inhibitors & Remibrutinib
In this episode of the Science of Skin Podcast, Dr. Ted Lain sits down with Dr. Sarina Elmariah, MD, PhD, professor of dermatology at UC San Francisco and director of the UCSF Center for Itch and Neurosensory Disorders, for a deep dive into chronic spontaneous urticaria (CSU).
Dr. Elmariah breaks down the role of Bruton's tyrosine kinase (BTK) in mast cell degranulation and explains how it sits at the center of the histamine release cascade. The conversation covers the difference between Type I (auto-allergic) and Type IIb (autoimmune) CSU pathways, available diagnostic tools like autologous…
The skinny
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