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433-Closed-Loop Wearable Neurostimulation System

This research presents a wearable, closed-loop system designed to treat hemifacial spasms (HFS) through a combination of high-precision sensing and targeted nerve stimulation. Integrated into a discreet eyewear platform, the device utilizes self-powered triboelectric sensors enhanced by specialized nanomaterials to detect minute, involuntary facial muscle contractions in real time. When the system identifies a spasm, it automatically triggers a customized electrical stimulator to deliver neuromodulation that inhibits abnormal neural activity. Clinical validation involving patients…

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