Latest / Intellectual Medicine / Biden's Prostate Cancer: The TRUTH Doctors Don't Want You To Know!
Transcript
- 0:00So the news is that former President Joe Biden has prostate
- 0:04cancer. But the good news, we're
- 0:06reassured, is that it is hormonally sensitive and that
- 0:11they can treat it and that they've been such advances in
- 0:15prostate cancer therapy that he can live for years.
- 0:19Holy cow, what a bundle of misinformation.
- 0:23Now, I'm a hope is that the president has a good run, right?
- 0:26Nobody wants to see anyone suffer.
- 0:28Well, let's break this down a little bit.
- 0:31How in the world can they feel so optimistic about what they're
- 0:34about to do to him? Hormonally sensitive.
- 0:40In conventional medical world, that means that they're going to
- 0:44castrate them. That means that they do androgen
- 0:47deprivation therapy. Why?
- 0:51The belief is that testosterone feeds cancer, that it helps
- 0:57cancer to initiate, and that it's like pouring gas on a fire.
- 1:02So if you take away the testosterone, the cancer will
- 1:05shrink and everything is good. Not so fast, everybody.
- 1:09We got to think long and hard about this.
- 1:12You got a man in his 80s. Well, any man for that matter.
- 1:15But in particular, let's focus on the case at hand.
- 1:19They found a nodule all right, then they biopsy him.
- 1:23That's the first mistake. A biopsy is unnecessary folks,
- 1:28to analyze the status of the prostate gland.
- 1:31There are now biometrics, lab testing that can give us really
- 1:35good information. And then there's an MRI of the
- 1:38prostate, non invasive. Finally, the PSMA test, prostate
- 1:43specific membrane antigen PET scan which can supersede the
- 1:48need for a biopsy. The Gleason score at that point
- 1:53is irrelevant. They said well, you know, the
- 1:56biopsy showed you had a Gleason score of a nine, which is an
- 2:00aggressive form. You don't need that information.
- 2:03When is evidence that it's already in the bone?
- 2:06That's declaration of its status.
- 2:09So what do they do? They castrate.
- 2:12Let's think about what that does.
- 2:13What happens when you castrate a man with prostate cancer?
- 2:18There are several things that are almost inevitable.
- 2:22First amongst them, increase in heart disease risk.
- 2:26There's an increased risk of heart attack, an increased risk,
- 2:30almost inevitable consequence of muscle atrophy, bone thinning,
- 2:37tripping and falling. You lose power, you lose
- 2:40balance. Why?
- 2:41Not only are the muscles weakened, the brain gets weak.
- 2:46Cognitive function declines. Dementia risk increases.
- 2:51The mood can be depressed. Testosterone is essential for
- 2:55proper brain functioning. You eliminate it at your own
- 3:00peril. It weakens the immune system.
- 3:03Risk of infection goes up. Risk of seizures goes up.
- 3:07See see where this is going. You have an octogenarian man
- 3:13with a weak brain to begin with and a tendency to fall.
- 3:19Then you're going to whack his testosterone, you're going to
- 3:21castrate him, and all these bad things are going to happen.
- 3:26How in the world can we feel good about that?
- 3:29What? How did medicine get stuck in
- 3:33this space? Well, I think we should talk
- 3:36about that, right? Because the dogma is powerful.
- 3:41Testosterone feeds cancer. Block testosterone.
- 3:45Cancer gets better. What I really care about, what
- 3:49you should care about, is not only the state of the cancer,
- 3:52we'd all prefer it not to be there, but the global vitality.
- 3:56What is our health like? Joe Biden is very unlikely to
- 4:01die from prostate cancer. If he trips and falls and breaks
- 4:05his hip, his likelihood that he'll die afterwards is pretty
- 4:09high. At that point, his oncologist
- 4:11and his urologist declare victory.
- 4:13Hey, our treatment worked. He didn't die of cancer.
- 4:16He gets a heart attack. Once again, didn't die of
- 4:19cancer, treatment worked. See where I'm going with this?
- 4:22The way he had conventional medicine cures prostate cancer
- 4:26is to have you die first from something else.
- 4:29Like that's a great achievement. Worse than death would be a
- 4:33progressive accelerated mental decline.
- 4:37What a horrible path. What a bad thing to do to a
- 4:41person. And yet, how much have we been
- 4:45led to believe is the only path? It isn't.
- 4:50There are other approaches that could be considered, but let's
- 4:52reflect on how we got here. How do we get to this point?
- 4:58In the 1940s and 50s, Doctor Huggins, very esteemed
- 5:01physician, a Nobel laureate, noted that when dogs who had
- 5:07prostate cancer implanted on them were castrated, the
- 5:12prostate cancer went away. Interesting.
- 5:16So he extrapolated that into some human cases, taking the
- 5:19observation that in some of these cases there was a
- 5:24reduction in the prostate cancer tumors that became the dogma
- 5:30that became accepted fund of knowledge.
- 5:34And it's been that way really since the 1950s.
- 5:38And what has occurred over the decades is that an entire
- 5:42multibillion dollar treatment intervention industry has been
- 5:48built on that foundation. When that happens, folks, it's
- 5:52really hard to talk that dog off the meat wagon.
- 5:56This dogma is tough to change. Think about it.
- 6:00Who's going to be motivated to consider it an alternative when
- 6:04pharmaceutical companies are making a killing, producing ever
- 6:08more powerful castration drugs, when doctors and hospitals are
- 6:14harvesting prostate glands or radiating them, are going on
- 6:18this treadmill of therapy? You would expect that with all
- 6:23of this advance in treatment may be a profound benefit to
- 6:27mankind, to the outcomes. We'll talk about how Doctor
- 6:31Huggins theories and evidence has been recently challenged.
- 6:36But let's look at the evidence of benefit, or I should say the
- 6:39lack thereof. Since 2012, the death rate per
- 6:42capita from prostate cancer flat as a pancake.
- 6:47It ain't going down. How about when I read in the
- 6:50newspaper article and they were saying that the doctor, well,
- 6:53you know, they've been great advances in prostate cancer
- 6:56therapy. Folks, the advances are more
- 6:59illusion than reality. You have to look past the
- 7:04summary of the article. In 1975, the five year survival
- 7:11rate for metastatic prostate cancer to the bone was 30
- 7:15percent. 1975, it's a great year.
- 7:19It's in high school. What fun.
- 7:21Anyhow, back to the topic at hand, 30% Now we've had great
- 7:26advances. And in 2020, the five year
- 7:30survival rate for metastatic prostate cancer was 37%.
- 7:36Look, I get it, it's a nudge in the right direction, but at what
- 7:39price? And it certainly is not a
- 7:41breakthrough. This is not what I expect when
- 7:45things work. When things work, the death rate
- 7:49per capita should decline. When things work, the five year
- 7:53survival rate should elevate significantly, not
- 7:56incrementally. And were the sort of lack of
- 8:01compelling benefit the only issue at hand, I could live with
- 8:05that. The problem is the treatments
- 8:07that are being promoted cause harm.
- 8:11I already shared with you the problems with androgen
- 8:13deprivation therapy. The brain, the muscle, the body,
- 8:16the bone. There is a mutual bias when men
- 8:22are faced with a scenario, right?
- 8:25Oh my goodness, I have prostate cancer.
- 8:28Oh, how horrible. It's in the bone.
- 8:30That's not such a good thing. What am I going to do about it?
- 8:33Well, we're going to put you on this drug.
- 8:35You're going to grow breasts, you're going to get fat, tired,
- 8:38weak. You're going to lose your
- 8:39erection, your sex drive, your confidence, your motivation.
- 8:43Your brain's going to get foggy, your risk of dementia's going to
- 8:45go up, and your risk of heart attack will go up.
- 8:47But you know, it's what we got and it'll keep you alive.
- 8:54I'm not so sure. Look at the evidence again.
- 8:59Enzalutamide is 1 of the androgen deprivation of sort of
- 9:04testosterone blocking therapies. And I highlight that particular
- 9:07drug because of a study that was published that showed in the
- 9:12summary when you block testosterone with this drug,
- 9:16there was a significant increase in survival.
- 9:21Now when you read about significance or when a doctor
- 9:25talks about it or when they summarize an article or a study
- 9:28about it, significance is a mathematical equation,
- 9:33statistically significant. Is it clinically relevant and is
- 9:39it worth the price of admission? Well, this particular study, the
- 9:43median survival on the drug was 32.4 months compared to the
- 9:49placebo, which was 30.2 months, a differential of about two
- 9:55months. Now look, if I get two more
- 9:58months of life, yeah, sign me up.
- 10:00I kind of like being alive. I understand the end comes.
- 10:04And were that the only metric, right, we could be on board.
- 10:09The problem is conventional medicine and a lot of these
- 10:13studies, it's very easy to measure life and death.
- 10:15Are they alive or not? If they're alive, that's good,
- 10:20but at what price? Are men undergoing this kind of
- 10:24treatment fully alive? Or are they just existing,
- 10:29waiting to die? But before they die, they
- 10:32wither? There must be a better way.
- 10:35How are we going to find that out?
- 10:37How do we get there from where we are?
- 10:39We've got this incredible fortress in front of us of big
- 10:43pharma, conventional medicine, hospitals, everybody, everybody
- 10:49is thriving with the status quo. To arrive at something fully
- 10:54different, it requires it's going to require a grass roots
- 10:57effort because there's never going to be a pharmaceutical
- 11:01company that will put forth extensive research on non
- 11:06patentable drugs, on non patentable treatments, even if
- 11:11they will hold merit, simply not in their financial best
- 11:14interest. Nor will they put out big
- 11:17studies analyzing adverse effects of their treatment not
- 11:20in their best interest. When I read these studies, there
- 11:24tends to be silence regarding quality of life issues.
- 11:28They're harder to measure and they get therefore diminished in
- 11:33their relevance. So as an individual gentleman,
- 11:38you need to make these decisions, you need to be
- 11:40assertive and you need the information to do it.
- 11:42The options aren't merely accept the therapy that's offered or
- 11:48wither and die. You know, there are other
- 11:50approaches that can be considered.
- 11:52We talk about them with repurposed drugs that may have
- 11:56value, but how about this for a a change in perception?
- 12:01It turns out this concept of testosterone stimulating
- 12:05prostate cancer simply may not be true.
- 12:09It was Doctor Abraham Morganteller in his fantastic
- 12:12book Testosterone for Life. He did some of the research
- 12:15looking back to Doctor Huggins original conclusions, and when
- 12:19he did a deep study regarding the origins of that connection,
- 12:25he found it boiled down to 1 case study that became the basis
- 12:32for the presumption that testosterone feeds cancer.
- 12:36One case study and it became so dogmatic and has remained so
- 12:41dogmatic that to actually challenge it with real research
- 12:46would almost be tantamount to an unethical study.
- 12:50We're going to take men and what?
- 12:52Give them testosterone or we're going to take men and we're not
- 12:56going to castrate them, right? Yeah, why not?
- 13:00Why not think differently? We know the castration therapy,
- 13:03at least now, you know, benefits.
- 13:05Yeah, not so much. Harm almost guaranteed.
- 13:09Well, it turns out that there are some innovative researchers
- 13:13that have studied this at Johns Hopkins.
- 13:16They are exploring and have explored something called
- 13:19bipolar androgen therapy. And what it boils down to is
- 13:24putting men with prostate cancer on high doses of testosterone
- 13:31and then crashing it down low with androgen blocking and doing
- 13:35this in cycles. It was motivated by men who have
- 13:41had their prostate removed. They went on hormone blocking
- 13:45therapy. And what happens every time?
- 13:50Eventually the PSA starts to climb and the cancer comes back.
- 13:55That is almost inevitable. If you don't die from something
- 13:58else first, this is your fate. And as it starts to climb, it's
- 14:03referred to as castration resistant therapy and what
- 14:08conventional medicine does. They really don't know what to
- 14:11do then it's really hard. The drugs are awful.
- 14:14We can talk more about those. They have ghastly side effects,
- 14:18marginal to no benefit. They double down right, block it
- 14:21even harder. Well, at Hopkins, they noted the
- 14:26theory that may be possible, that by shifting these levels of
- 14:31testosterone, the prostate cancer cells may not like that.
- 14:36And it turns out one of the reasons why it has not held up
- 14:40that testosterone equals prostate cancer risk is because
- 14:45there are two different levels to consider.
- 14:47There's your blood level of testosterone that can be
- 14:50measured. That is not the same folks as
- 14:53the level in the prostate gland. The prostate gland saturates
- 14:58with testosterone after which it can't absorb anymore.
- 15:02The glass is full. You can double up your blood
- 15:05level. It's not going to affect the
- 15:06gland. Now we know from studies the
- 15:09consensus amongst andrologist men and women who specialize in
- 15:14hormone therapy. Consensus is a testosterone does
- 15:18not increase prostate cancer risk.
- 15:21A testosterone does not increase cardiovascular risk, nor does it
- 15:27increase prostatic hypertrophy, enlarging of the gland.
- 15:30All right, that's all well and good, but how about if you
- 15:33already have prostate cancer? This bipolar therapy when
- 15:38applied to men who had castration resistant prostate
- 15:42cancer, turns out many of them had a positive effect.
- 15:47That is, the testosterone of the PSA levels declined and they
- 15:52gained the benefit of testosterone.
- 15:54Hooray, a restoration of vitality.
- 15:57That's a good thing. Now taking that research, that
- 16:02theory and applying it to men who have not had to suffer the
- 16:07consequence of castration but are having a progression of
- 16:11their disease is a leap of clinical judgement that has not
- 16:16been proven to work, that might in fact fail, that might in fact
- 16:20actually accelerate cancer. That's a possibility, but
- 16:24there's evidence that it may actually be beneficial.
- 16:28And the only way we're going to figure that out is by a
- 16:31combination of forward thinking clinicians.
- 16:35You know, I count myself as one and open minded patients willing
- 16:40to step out of the pathway of conventional care to consider
- 16:44another approach. Here's what they're going to get
- 16:47for their reward. Preserve vitality that's almost
- 16:51guaranteed. They're not going to have
- 16:53castration. They're not going to suffer that
- 16:55host of horrible effects. All right, that's all good.
- 17:00But will the prostate cancer itself be suppressed?
- 17:04Will their survival be better than or as good as the men that
- 17:10are getting castrated? I believe there's reason to
- 17:13believe that it will be, but I couldn't tell you that that's
- 17:17been proven or demonstrated. I can share with you there are
- 17:20men on this pathway right now, and I'm grateful for them and
- 17:24you should be too because we're tracking these outcomes.
- 17:27We do research at intellectual medicine.
- 17:29We keep tabs on things. We like to know how they're
- 17:32working. We'll continue to report that to
- 17:34you guys. But my point today is to
- 17:37emphasize the avoidance of harm, right?
- 17:41Isn't that rule number one? First, do no harm.
- 17:44So when, if ever, should you consider castration?
- 17:48If you have prostate cancer, you, in my view, never, never,
- 17:54ever do you do it unless you are desperately sick.
- 17:57If your PSA is going up and the doctor says, well, that is a
- 18:02chemical relapse. What nonsense.
- 18:05We're treating a lab study. We're giving you this
- 18:08devastating therapy guaranteed to cause harm, not because
- 18:13you're manifesting any symptom, but because the lab is going up
- 18:17a little bit. We know there's no correlation.
- 18:19I should say there's very weak correlation between APSA and the
- 18:24status of the prostate cancer in the body.
- 18:28It can be contained within that capsule with APSA level that is
- 18:33going up and up and up. It can still be contained.
- 18:37Patient of mine with APSA went from 100 up to 300 roughly.
- 18:42Scary. I mean 100 is scary but imagine
- 18:45jumping a 300 bone scan. PSMA studies, no metastatic
- 18:51process, all contained within the prostate gland.
- 18:55No androgen deprivation therapy for my guy.
- 18:58He feels great. So do not let them do this to
- 19:02you for a number of reasons #1 is going to harm you #2 no
- 19:05evidence that's going to extend your life.
- 19:07And #3 we know resistance to castration or androgen
- 19:12deprivation therapy will occur there.
- 19:16When it occurs that ADT treatment is no longer valuable,
- 19:21no longer has an effect, you may in fact need that later.
- 19:26When might you need it? When and if only if the prostate
- 19:32cancer hits the bones. That's where it usually goes
- 19:35when it metastasizes. It hits the bones and it's
- 19:38causing excruciating pain. When you're at that level, then
- 19:42the therapy is warranted and it can't alleviate the pain.
- 19:46But bear in mind it's nearing the end of the game.
- 19:49You may still have a couple years in you, but by all means
- 19:52when the pain is excruciating then it's worth the price of a
- 19:57side effect to get out of the pain.
- 19:59I get that right and that's why you hold off on it.
- 20:03Wait until you desperately need it for several reasons. 1 you
- 20:09may never need it. The cancer may stay within the
- 20:12within the capsule of a gland. The span of your life and APSA
- 20:17level doesn't tell you whether or not that's the case.
- 20:20No imaging study can declare it, except for maybe the PSMA.
- 20:26So you want to hold this in reserve in the event you need it
- 20:29in the hope that you never will wait until you see the whites of
- 20:33their eyes, right? Then you can fire it and then
- 20:36you'll have preserved its therapeutic value, its impact.
- 20:41So I know it sounds unnerving to contemplate APSA going up, and
- 20:47it is a bit unnerving to think that the only time we would
- 20:53intervene with androgen deprivation therapy is when
- 20:57symptoms compel us to. The prostate cancer can go to
- 21:00other organs. Liver, no kidney, it can go
- 21:04other places, but mostly bone. Bear in mind, as you have these
- 21:09reflections, you or friends or others, that the vast majority
- 21:14of men with prostate cancer do not die from the prostate cancer
- 21:17itself. Yes, it happens, and yes, it's
- 21:21sad when it does, but the objective is to not pursue
- 21:26treatments of little value that can cause harm when there are
- 21:31other options that you can consider and that the goal
- 21:36maintaining vitality may hold on to your brain, hold on your
- 21:40muscle. As sad as the President Biden's
- 21:43diagnosis is, and as hopeful as we all are that will have a good
- 21:49outcome, I shudder to think the consequence of giving this poor
- 21:53man castration treatment. Are these the same people that
- 21:57were advising him about his mental state years ago?
- 22:00Because I don't see a good outcome with a man with
- 22:04predisposed towards falling cognitive impairment and
- 22:09accelerating of those conditions.
- 22:12So every man has to make his own choice and it's not wrong.
- 22:16It's not wrong to pick androgen deprivation therapy.
- 22:20My objection is the exclusivity of this being offered as a
- 22:24pathway forward and the failure of medicine to seriously
- 22:29contemplate alternatives in the face of this type of hideous
- 22:34adverse profile with marginal merit.
- 22:38Well, together, you and I and people like us, we can craft
- 22:43that new pathway. It's not going to happen from
- 22:46the top down. Nobody from the pharmaceutical
- 22:49world or the hospital world is likely to embrace the concepts
- 22:54that I'm sharing with you. But you know it's out there, and
- 22:58I encourage you to do your homework and be cautious.
- 23:02Do not fly out of the country going to some tertiary care
- 23:07center that promises to cure cancer.
- 23:09You'll end up broke and the cancer will still be there.
- 23:12I've seen it far too many times, right?
- 23:15This is chronic suppression we're talking about.
- 23:18All right, folks. So the president, President
- 23:20Biden has prostate cancer. You know, it's almost
- 23:23inevitable. We talked about this.
- 23:26By the time a man hits 90, there's a 60 to 80% chance a lot
- 23:30of prostate cancer cells in the gland.
- 23:34If something is that prevalent, we can consider it a normal
- 23:37progression. Most of these, the vast majority
- 23:40of them, are going to be atypical dormant cells sleeping
- 23:45in the gland. Let them sleep.
- 23:47Never biopsy. Do biometrics and MRI if you
- 23:51must. Avoid castration at all cost.
- 23:55Don't let them cut out your prostate gland and do not
- 23:58irradiate it. These are the tenants of the the
- 24:02protocol I've developed based upon my research, the
- 24:05observation of adverse effect. We'll continue this mission
- 24:10together well indefinitely until it rises to a level where men
- 24:16have equal access to this information.
- 24:19And yet they have they can pick a different pathway.
- 24:23If I had President Biden in my office, I would direct him in
- 24:27another path and I believe it'd be to his benefit.
- 24:30But I've got you and we can continue our conversation.
- 24:34So thanks for your time and tuning in.
- 24:36I'll talk to you soon.