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ASHP Best Practice Award 2023: Real-World Clinical Impact of an In-House Dihydropyrimidine Dehydrogenase (DPYD) Genotyping Test on Fluoropyrimidine Dosing and Toxicity at a Multisite Cancer Center

In this episode, the team from the Atrium Health System discuss their award-winning submission to the ASHP Best Practices. They will share how their program implemented a novel pharmacist-led DPYD testing program with CDS integration and demonstrated pre-treatment testing with genotype-guided fluoropyrimidine dosing improves patient safety by mitigating severe toxicities and hospitalizations in DPYD variant carriers.

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