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565-Planetary Microbiome Structure and Global Gene Flow

This research presents a planetary-scale analysis of over 85,000 metagenomes to establish a comprehensive framework for understanding global microbial habitats. By integrating taxonomic and functional data, the authors identify distinct habitat clusters across aquatic, terrestrial, anthropogenic, and host-associated environments. A key finding is the role of generalist species, which possess the metabolic versatility to bridge ecologically disparate boundaries and facilitate horizontal gene transfer. These generalists act as critical mediators for the global dissemination of antimicrobial…

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