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Does Psilocybin Work for OCD? Two Decades of Research Insights with Dr. Francisco Moreno
What can two decades of clinical research teach us about psilocybin's potential for treating obsessive-compulsive disorder (OCD)? In this episode, we sit down with Dr. Francisco Moreno, a pioneer in psychedelic-assisted treatment research, to trace the arc of his work - from his landmark 2006 trial, one of the first modern investigations of psilocybin for OCD, to his newly published 2026 randomized clinical trial testing repeated psilocybin doses in a larger patient sample.
We discuss the design, safety, and efficacy findings from both studies; what changed methodologically between them; and…
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