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Cancer Isn’t Just Genetic — It’s Mitochondrial Network Warfare (Fission, Fusion, Metastasis + Drug Resistance)

In this Energy Code Deep Dive, Dr. Mike breaks down a major shift in cancer biology: mitochondria aren’t static “powerhouses”, they’re a dynamic network that tumors actively remodel to drive survival. Based on the review “Mitochondrial Dynamics and Cancer Mechanisms and Targeted Therapy,” we explore how cancer systematically tilts mitochondrial behavior toward hyperactive fission (DRP1), reduced fusion (MFN1/2, OPA1 disruption), altered mitophagy, and directed transport — and how that network remodeling supports the core hallmarks of malignancy: metabolic plasticity, rapid proliferation…

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