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The Accidental Pill: How a Failed Testosterone Created Oral Progestogen
The Accidental Pill: How a Failed Testosterone Created Oral Progestogen
A discovery in a Berlin lab in 1938 turned a failed oral testosterone into the first oral progestogen, introducing a tablet option where previously only injections existed and creating a drug that required up to 700 mg over 10-14 days to transform the endometrium. How did a single ethynyl group produce a medicine that changed women’s treatment yet could not prevent ovulation?
In this episode, we tell how four chemists at Schering AG synthesized ethisterone, how it reached markets across countries under multiple brand…
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