1580-Multi-modal Tumor Profiling in Ovarian Cancer
The paper describes the Swiss Tumor Profiler (TuPro) project, a prospective research initiative investigating the clinical utility of multi-omics molecular profiling for patients with high-grade serous ovarian cancer. By integrating data from DNA, RNA, proteins, and functional drug assays within a four-week window, researchers provided personalized treatment recommendations that altered standard care for 76% of participants. This comprehensive approach identified whole-genome amplification as a key predictor of poor survival and discovered that chemotherapy significantly increases cancer cell…
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