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Week 1 2025 College Football Picks for the 10 Biggest Games!

College football Week 1 is here, and we’re breaking down the 10 biggest games of 2025 with picks, odds, and analysis. From Texas vs Ohio State in the Horseshoe to Clemson vs LSU in the Battle of the Death Valleys, it’s a stacked opening weekend.We cover:

1:02 Ohio State vs Texas – Arch Manning’s chance against Ryan Day’s Buckeyes

6:17 Clemson vs LSU – Cade Klubnik vs Garrett Nussmeier, huge trenches battle

11:51 Miami vs Notre Dame – Carson Beck leads the Canes against Irish QB inexperience

17:00 Auburn vs Baylor – Hugh Freeze’s offense vs Dave Aranda’s Bears

21:49 Nebraska vs Cincinnati –…

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