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Latest / The Hunter Williams Podcast

The MOTS-c Masterclass | Complete Researcher’s Guide (2026)

Links, cheatsheet, private group and more: ⁠https://hunterwilliamshealth.com/links

In this masterclass I break down what MOTS-c actually is. It's a tiny peptide your mitochondria make when you exercise. It's the only major peptide coded inside the mitochondrial genome, not the cell nucleus.

I get into how it flips the AMPK switch, your cell's main fuel gauge. I cover the dual action that lets it travel into the nucleus and turn on antioxidant genes. That part makes it pretty unique.

Then I walk through the practical stuff. Who's a good candidate and who should skip it. My full dosing tiers…

The skinny

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