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Tavapadon as Adjunctive Therapy for Parkinson Disease - TEMPO-3 Trial
The provided sources detail phase 3 clinical trial results for tavapadon, a novel, once-daily dopamine D1/D5 receptor agonist designed to treat Parkinson disease. In the TEMPO-1 study, fixed doses of the medication significantly improved motor function and daily living experiences for patients in the early stages of the disease. Simultaneously, the TEMPO-3 trial demonstrated that tavapadon effectively increases "good-on-time" and reduces daily "off-time" when used as an add-on therapy for patients experiencing fluctuations while on levodopa. Researchers observed that the drug's selective…
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